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                  Page - 1 of 1                  Record - 1 of 4   [TOP]
Compound ID1440
Compound Structure
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Plant SourceChromolaena odorata     Common Name:Siam Weed, Christmas Bush, Common Floss Flower
Source FamilyAsteraceae (Compositae)
OriginNeotropics, Worldwide
Plant Part UsedFlower
Extract
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin sulphate (2.50 µg/ml), Isoniazid (0.06 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedIsosakuranetin
PubChem ID   160481
Ethnomedicinal InformationTreat skin wounds
PubMed ID [Source Literature]15202555, 10811796
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Flavonoid, Ether, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight286.084
Molecular FormulaC16H14O5
SMILESO1[C@@H](CC(=O)c2c1cc(O)cc2O)c1ccc(OC)cc1
XLogP1.416
PSA75.990
H-bond Donor2
H-bond Acceptor5
No. of Rotatable Bond Count2
No. of Rings3
No. of N0
No. of O5
No. of S0
Reference(s)1) Suksamrarn, A., Chotipong, A., Suavansri, T., Boongird, S., Timsuksai, P., Vimuttipong, S., et al. (2004). Antimycobacterial activity and cytotoxicity of flavonoids from the flowers of Chromolaena odorata. Arch Pharm Res 27, 507u511

2) Schmidt GJ, Schilling EE.Phylogeny and biogeography of Eupatorium (Asteraceae: Eupatorieae) based on nuclear ITS sequence data.Am J Bot. 2000 May;87(5):716-26

Curator

                  Record - 2 of 4   [TOP]
Compound ID1441
Compound Structure
DOWNLOAD:
Plant SourceChromolaena odorata     Common Name:Siam Weed, Christmas Bush, Common Floss Flower
Source FamilyAsteraceae (Compositae)
OriginNeotropics, Worldwide
Plant Part UsedFlower
Extract
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin sulphate (2.50 µg/ml), Isoniazid (0.06 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml200 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified4` - Hydroxy - 5, 6, 7 - Trimethoxyflavanone
PubChem ID   244387
Ethnomedicinal InformationTreats skin wounds
PubMed ID [Source Literature]15202555, 10811796
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Flavonoid, Ether, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight330.110
Molecular FormulaC18H18O6
SMILESO1C(CC(=O)c2c1cc(OC)c(OC)c2OC)c1ccc(O)cc1
XLogP1.491
PSA74.220
H-bond Donor1
H-bond Acceptor6
No. of Rotatable Bond Count4
No. of Rings3
No. of N0
No. of O6
No. of S0
Reference(s)1) Suksamrarn, A., Chotipong, A., Suavansri, T., Boongird, S., Timsuksai, P., Vimuttipong, S., et al. (2004). Antimycobacterial activity and cytotoxicity of flavonoids from the flowers of Chromolaena odorata. Arch Pharm Res 27, 507u511

2) Schmidt GJ, Schilling EE.Phylogeny and biogeography of Eupatorium (Asteraceae: Eupatorieae) based on nuclear ITS sequence data.Am J Bot. 2000 May;87(5):716-26

Curator

                  Record - 3 of 4   [TOP]
Compound ID1442
Compound Structure
DOWNLOAD:
Plant SourceChromolaena odorata     Common Name:Siam Weed, Christmas Bush, Common Floss Flower
Source FamilyAsteraceae (Compositae)
OriginNeotropics, Worldwide
Plant Part UsedFlower
Extract
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin sulphate (2.50 µg/ml), Isoniazid (0.06 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml200 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedAcacetin
PubChem ID   5280442
Ethnomedicinal InformationTreats skin wounds
PubMed ID [Source Literature]15202555, 10811796
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Flavonoid, Ether, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight284.068
Molecular FormulaC16H12O5
SMILESO1c2c(c(=O)cc1c1ccc(OC)cc1)c(O)cc(O)c2
XLogP1.645
PSA66.760
H-bond Donor2
H-bond Acceptor4
No. of Rotatable Bond Count2
No. of Rings3
No. of N0
No. of O5
No. of S0
Reference(s)1) Suksamrarn, A., Chotipong, A., Suavansri, T., Boongird, S., Timsuksai, P., Vimuttipong, S., et al. (2004). Antimycobacterial activity and cytotoxicity of flavonoids from the flowers of Chromolaena odorata. Arch Pharm Res 27, 507u511

2) Schmidt GJ, Schilling EE.Phylogeny and biogeography of Eupatorium (Asteraceae: Eupatorieae) based on nuclear ITS sequence data.Am J Bot. 2000 May;87(5):716-26

Curator

                  Record - 4 of 4   [TOP]
Compound ID1443
Compound Structure
DOWNLOAD:
Plant SourceChromolaena odorata     Common Name:Siam Weed, Christmas Bush, Common Floss Flower
Source FamilyAsteraceae (Compositae)
OriginNeotropics, Worldwide
Plant Part UsedFlower
Extract
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin sulphate (2.50 µg/ml), Isoniazid (0.06 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml200 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedLuteolin
PubChem ID   5280445
Ethnomedicinal InformationTreats skin wounds
PubMed ID [Source Literature]15202555, 10811796
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Flavonoid, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight286.048
Molecular FormulaC15H10O6
SMILESO1c2c(c(=O)cc1c1cc(O)c(O)cc1)c(O)cc(O)c2
XLogP0.592
PSA97.990
H-bond Donor4
H-bond Acceptor5
No. of Rotatable Bond Count1
No. of Rings3
No. of N0
No. of O6
No. of S0
Reference(s)1) Suksamrarn, A., Chotipong, A., Suavansri, T., Boongird, S., Timsuksai, P., Vimuttipong, S., et al. (2004). Antimycobacterial activity and cytotoxicity of flavonoids from the flowers of Chromolaena odorata. Arch Pharm Res 27, 507u511

2) Schmidt GJ, Schilling EE.Phylogeny and biogeography of Eupatorium (Asteraceae: Eupatorieae) based on nuclear ITS sequence data.Am J Bot. 2000 May;87(5):716-26

Curator


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