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                  Page - 1 of 1                  Record - 1 of 4   [TOP]
Compound ID3390
Compound Structure
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Plant SourceErythrina gibbosa     Common Name:NR
Source FamilyFabaceae
OriginPanamanian
Plant Part UsedNR
ExtractNR
Target BacteriaMycobacterium tuberculosis H37Rv
Assay / Test DoneAgar Dilution - Streak Assay
Positive Control Used (conc.)NR
Inhibition [%]NR
Activity [MIC] µg/ml>=25 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedErygibisoflavone
PubChem ID   392442
Ethnomedicinal InformationNR
PubMed ID [Source Literature]9828037
Extract PreparationNR
Chemical Classification [Active Compound]Aromatic, Tetracyclic, Flavonoid, Benzopyran, Phenol
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]NR
Molecular Weight354.110
Molecular FormulaC20H18O6
SMILESO1C(C=Cc2c1c(C1COc3c(C1=O)c(O)cc(O)c3)ccc2O)(C)C
XLogP1.167
PSA96.220
H-bond Donor3
H-bond Acceptor6
No. of Rotatable Bond Count1
No. of Rings4
No. of N0
No. of O6
No. of S0
Reference(s)1) Mitscher LA, Baker W.Tuberculosis: a search for novel therapy starting with natural products.Med Res Rev. 1998 Nov;18(6):363-74

CuratorWvarsha, keyamukherjee, rachanake

                  Record - 2 of 4   [TOP]
Compound ID3391
Compound Structure
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Plant SourceErythrina gibbosa     Common Name:NR
Source FamilyFabaceae
OriginPanamanian
Plant Part UsedNR
ExtractNR
Target BacteriaMycobacterium tuberculosis H37Rv
Assay / Test DoneAgar Dilution - Streak Assay
Positive Control Used (conc.)NR
Inhibition [%]
Activity [MIC] µg/ml8 - 25 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedErythrabyssin 2
PubChem ID   10408212
Ethnomedicinal InformationNR
PubMed ID [Source Literature]9828037
Extract PreparationNR
Chemical Classification [Active Compound]Aromatic, Tetracyclic, Chromene, Benzopyran, Phenol, Prenylated
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]NR
Molecular Weight392.199
Molecular FormulaC25H28O4
SMILESO1[C@@H]2[C@H](c3c1c(c(O)cc3)CC=C(C)C)COc1c2cc(c(O)c1)CC=C(C)C
XLogP4.735
PSA58.920
H-bond Donor2
H-bond Acceptor4
No. of Rotatable Bond Count4
No. of Rings4
No. of N0
No. of O4
No. of S0
Reference(s)1) Mitscher LA, Baker W.Tuberculosis: a search for novel therapy starting with natural products.Med Res Rev. 1998 Nov;18(6):363-74

CuratorWvarsha,keyamukherjee, rachanake

                  Record - 3 of 4   [TOP]
Compound ID3392
Compound Structure
DOWNLOAD:
Plant SourceErythrina gibbosa     Common Name:NR
Source FamilyFabaceae
OriginPanamanian
Plant Part UsedNR
ExtractNR
Target BacteriaMycobacterium tuberculosis H37Rv
Assay / Test DoneAgar Dilution - Streak Assay
Positive Control Used (conc.)NR
Inhibition [%]NR
Activity [MIC] µg/ml8 - 25 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedPhaseolidine
PubChem ID   119268
Ethnomedicinal InformationNR
PubMed ID [Source Literature]9828037
Extract PreparationNR
Chemical Classification [Active Compound]Aromatic, Tetracyclic, Benzopyran, Benzofuranoid, Prenylated
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]NR
Molecular Weight324.136
Molecular FormulaC20H20O4
SMILESO1[C@@H]2[C@H](c3c1c(c(O)cc3)CC=C(C)C)COc1c2ccc(O)c1
XLogP3.265
PSA58.920
H-bond Donor2
H-bond Acceptor4
No. of Rotatable Bond Count2
No. of Rings4
No. of N0
No. of O4
No. of S0
Reference(s)1) Mitscher LA, Baker W.Tuberculosis: a search for novel therapy starting with natural products.Med Res Rev. 1998 Nov;18(6):363-74

CuratorWvarsha, keyamukherjee, rachanake

                  Record - 4 of 4   [TOP]
Compound ID3393
Compound Structure
DOWNLOAD:
Plant SourceErythrina gibbosa     Common Name:NR
Source FamilyFabaceae
OriginPanamanian
Plant Part UsedNR
ExtractNR
Target BacteriaMycobacterium smegmatis
Assay / Test DoneAgar Dilution - Streak Assay
Positive Control Used (conc.)NR
Inhibition [%]NR
Activity [MIC] µg/ml0.78 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedErythrabyssin 2
PubChem ID   10408212
Ethnomedicinal InformationNR
PubMed ID [Source Literature]9828037
Extract PreparationNR
Chemical Classification [Active Compound]Aromatic, Tetracyclic, Chromene, Benzopyran, Phenol, Prenylated
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]NR
Molecular Weight392.199
Molecular FormulaC25H28O4
SMILESO1[C@@H]2[C@H](c3c1c(c(O)cc3)CC=C(C)C)COc1c2cc(c(O)c1)CC=C(C)C
XLogP4.735
PSA58.920
H-bond Donor2
H-bond Acceptor4
No. of Rotatable Bond Count4
No. of Rings4
No. of N0
No. of O4
No. of S0
Reference(s)1) Mitscher LA, Baker W.Tuberculosis: a search for novel therapy starting with natural products.Med Res Rev. 1998 Nov;18(6):363-74

CuratorWvarsha, keyamukherjee, rachanake


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