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                  Page - 1 of 1                  Record - 1 of 12   [TOP]
Compound ID3940
Compound Structure
DOWNLOAD:
Plant SourceButea monosperma (LAM.) TAUB.     Common Name:Flame of the Forest
Source FamilyFabaceae
OriginTropical Southern Asia, Pakistan, India, Bangladesh
Plant Part UsedFlower
ExtractEtOAc and MeOH
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin Sulphate (2.5 µg/ml), Isoniazid (0.06 µg/ml), Rifampin (0.004 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml25 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedButin
PubChem ID   92775
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19336944
Extract PreparationThe dried flowers (15.0 kg) were milled and soaked successively with n - hexane, EtOAc and MeOH. The hexane, EtOAc and MeOH extracts were evaporated under reduced pressure to give the crude hexane extract (brownish syrup, 32.8 g), the EtOAc extract (dark brownish sticky solid, 102.7 g) and the MeOH extract (dark brownish sticky solid, 527.6 g)
Chemical Classification [Active Compound]Aromatic, Tricyclic, Flavonoid, Phenol
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]NR
Molecular Weight272.068
Molecular FormulaC15H12O5
SMILESO1[C@@H](CC(=O)c2c1cc(O)cc2)c1cc(O)c(O)cc1
XLogP1.326
PSA86.990
H-bond Donor3
H-bond Acceptor5
No. of Rotatable Bond Count1
No. of Rings3
No. of N0
No. of O5
No. of S0
Reference(s)1) Chokchaisiri R, Suaisom C, Sriphota S, Chindaduang A, Chuprajob T, Suksamrarn A.Bioactive flavonoids of the flowers of Butea monosperma.Chem Pharm Bull (Tokyo). 2009 Apr;57(4):428-32

CuratorVikramjitmandal, Keyamukherjee, najiya-beegum, swatigandhi

                  Record - 2 of 12   [TOP]
Compound ID3941
Compound Structure
DOWNLOAD:
Plant SourceButea monosperma (LAM.) TAUB.     Common Name:Flame of the Forest
Source FamilyFabaceae
OriginTropical Southern Asia, Pakistan, India, Bangladesh
Plant Part UsedFlower
ExtractEtOAc and MeOH
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin Sulphate (2.5 µg/ml), Isoniazid (0.06 µg/ml), Rifampin (0.004 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml12.5 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedButein
PubChem ID   5281222
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19336944
Extract PreparationThe dried flowers (15.0 kg) were milled and soaked successively with n - hexane, EtOAc and MeOH. The hexane, EtOAc and MeOH extracts were evaporated under reduced pressure to give the crude hexane extract (brownish syrup, 32.8 g), the EtOAc extract (dark brownish sticky solid, 102.7 g) and the MeOH extract (dark brownish sticky solid, 527.6 g)
Chemical Classification [Active Compound]Aromatic, Alkene. Chalcone, Phenol
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]NR
Molecular Weight272.068
Molecular FormulaC15H12O5
SMILESOc1c(C(=O)/C=C/c2cc(O)c(O)cc2)ccc(O)c1
XLogP2.019
PSA97.990
H-bond Donor4
H-bond Acceptor5
No. of Rotatable Bond Count3
No. of Rings2
No. of N0
No. of O5
No. of S0
Reference(s)1) Chokchaisiri R, Suaisom C, Sriphota S, Chindaduang A, Chuprajob T, Suksamrarn A.Bioactive flavonoids of the flowers of Butea monosperma.Chem Pharm Bull (Tokyo). 2009 Apr;57(4):428-32

CuratorVikramjitmandal, Keyamukherjee, najiya-beegum, swatigandhi

                  Record - 3 of 12   [TOP]
Compound ID3942
Compound Structure
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Plant SourceButea monosperma (LAM.) TAUB.     Common Name:Flame of the Forest
Source FamilyFabaceae
OriginTropical Southern Asia, Pakistan, India, Bangladesh
Plant Part UsedFlower
ExtractEtOAc and MeOH
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin Sulphate (2.5 µg/ml), Isoniazid (0.06 µg/ml), Rifampin (0.004 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml50 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound Identified(-)- Butrin
PubChem ID   164630
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19336944
Extract PreparationThe dried flowers (15.0 kg) were milled and soaked successively with n - hexane, EtOAc and MeOH. The hexane, EtOAc and MeOH extracts were evaporated under reduced pressure to give the crude hexane extract (brownish syrup, 32.8 g), the EtOAc extract (dark brownish sticky solid, 102.7 g) and the MeOH extract (dark brownish sticky solid, 527.6 g)
Chemical Classification [Active Compound]Aromatic, Tricyclic, Flavonoid, Ether, Phenol, Sugar
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]NR
Molecular Weight596.174
Molecular FormulaC27H32O15
SMILESO1[C@@H]([C@@H](O)[C@H](O)[C@@H](O)[C@@H]1Oc1cc([C@H]2Oc3c(C(=O)C2)ccc(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)CO)c3)ccc1O)CO
XLogP-1.319
PSA245.290
H-bond Donor9
H-bond Acceptor15
No. of Rotatable Bond Count7
No. of Rings5
No. of N0
No. of O15
No. of S0
Reference(s)1) Chokchaisiri R, Suaisom C, Sriphota S, Chindaduang A, Chuprajob T, Suksamrarn A.Bioactive flavonoids of the flowers of Butea monosperma.Chem Pharm Bull (Tokyo). 2009 Apr;57(4):428-32

CuratorVikramjitmandal, Keyamukherjee, najiya-beegum, swatigandhi

                  Record - 4 of 12   [TOP]
Compound ID3943
Compound Structure
DOWNLOAD:
Plant SourceButea monosperma (LAM.) TAUB.     Common Name:Flame of the Forest
Source FamilyFabaceae
OriginTropical Southern Asia, Pakistan, India, Bangladesh
Plant Part UsedFlower
ExtractEtOAc and MeOH
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin Sulphate (2.5 µg/ml), Isoniazid (0.06 µg/ml), Rifampin (0.004 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml25 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedMonospermoside
PubChem ID   42607524
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19336944
Extract PreparationThe dried flowers (15.0 kg) were milled and soaked successively with n - hexane, EtOAc and MeOH. The hexane, EtOAc and MeOH extracts were evaporated under reduced pressure to give the crude hexane extract (brownish syrup, 32.8 g), the EtOAc extract (dark brownish sticky solid, 102.7 g) and the MeOH extract (dark brownish sticky solid, 527.6 g)
Chemical Classification [Active Compound]Aromatic, Alkene, Chalcone, Phenol, Sugar
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]NR
Molecular Weight434.121
Molecular FormulaC21H22O10
SMILESO1[C@@H]([C@@H](O)[C@H](O)[C@@H](O)[C@@H]1Oc1cc(ccc1O)/C=C/C(=O)c1c(O)cc(O)cc1)CO
XLogP0.482
PSA177.140
H-bond Donor7
H-bond Acceptor10
No. of Rotatable Bond Count6
No. of Rings3
No. of N0
No. of O10
No. of S0
Reference(s)1) Chokchaisiri R, Suaisom C, Sriphota S, Chindaduang A, Chuprajob T, Suksamrarn A.Bioactive flavonoids of the flowers of Butea monosperma.Chem Pharm Bull (Tokyo). 2009 Apr;57(4):428-32

CuratorVikramjitmandal, Keyamukherjee, najiya-beegum, swatigandhi

                  Record - 5 of 12   [TOP]
Compound ID3944
Compound Structure
DOWNLOAD:
Plant SourceButea monosperma (LAM.) TAUB.     Common Name:Flame of the Forest
Source FamilyFabaceae
OriginTropical Southern Asia, Pakistan, India, Bangladesh
Plant Part UsedFlower
ExtractEtOAc and MeOH
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin Sulphate (2.5 µg/ml), Isoniazid (0.06 µg/ml), Rifampin (0.004 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml25 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound Identified(+)- Isomonospermoside
PubChem ID   42607822
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19336944
Extract PreparationThe dried flowers (15.0 kg) were milled and soaked successively with n - hexane, EtOAc and MeOH. The hexane, EtOAc and MeOH extracts were evaporated under reduced pressure to give the crude hexane extract (brownish syrup, 32.8 g), the EtOAc extract (dark brownish sticky solid, 102.7 g) and the MeOH extract (dark brownish sticky solid, 527.6 g)
Chemical Classification [Active Compound]Aromatic, Tricyclic, Flavonoid, Ether, Phenol, Sugar
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]NR
Molecular Weight434.121
Molecular FormulaC21H22O10
SMILESO1[C@@H]([C@@H](O)[C@@H](O)[C@@H](O)[C@@H]1Oc1cc(C2Oc3c(C(=O)C2)ccc(O)c3)ccc1O)CO
XLogP-0.211
PSA166.140
H-bond Donor6
H-bond Acceptor10
No. of Rotatable Bond Count4
No. of Rings4
No. of N0
No. of O10
No. of S0
Reference(s)1) Chokchaisiri R, Suaisom C, Sriphota S, Chindaduang A, Chuprajob T, Suksamrarn A.Bioactive flavonoids of the flowers of Butea monosperma.Chem Pharm Bull (Tokyo). 2009 Apr;57(4):428-32

CuratorVikramjitmandal, Keyamukherjee, najiya-beegum, swatigandhi

                  Record - 6 of 12   [TOP]
Compound ID3945
Compound Structure
DOWNLOAD:
Plant SourceButea monosperma (LAM.) TAUB.     Common Name:Flame of the Forest
Source FamilyFabaceae
OriginTropical Southern Asia, Pakistan, India, Bangladesh
Plant Part UsedFlower
ExtractEtOAc and MeOH
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin Sulphate (2.5 µg/ml), Isoniazid (0.06 µg/ml), Rifampin (0.004 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml50 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound Identified7, 3' , 4' - Tri - Hydroxyflavone
PubChem ID   5322065
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19336944
Extract PreparationThe dried flowers (15.0 kg) were milled and soaked successively with n - hexane, EtOAc and MeOH. The hexane, EtOAc and MeOH extracts were evaporated under reduced pressure to give the crude hexane extract (brownish syrup, 32.8 g), the EtOAc extract (dark brownish sticky solid, 102.7 g) and the MeOH extract (dark brownish sticky solid, 527.6 g)
Chemical Classification [Active Compound]Aromatic, Tricyclic, Flavonoid, Phenol
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]NR
Molecular Weight270.053
Molecular FormulaC15H10O5
SMILESO1c(c2cc(O)c(O)cc2)cc(=O)c2c1cc(O)cc2
XLogP1.246
PSA77.760
H-bond Donor3
H-bond Acceptor4
No. of Rotatable Bond Count1
No. of Rings3
No. of N0
No. of O5
No. of S0
Reference(s)1) Chokchaisiri R, Suaisom C, Sriphota S, Chindaduang A, Chuprajob T, Suksamrarn A.Bioactive flavonoids of the flowers of Butea monosperma.Chem Pharm Bull (Tokyo). 2009 Apr;57(4):428-32

CuratorVikramjitmandal, Keyamukherjee, najiya-beegum, swatigandhi

                  Record - 7 of 12   [TOP]
Compound ID3946
Compound Structure
DOWNLOAD:
Plant SourceButea monosperma (LAM.) TAUB.     Common Name:Flame of the Forest
Source FamilyFabaceae
OriginTropical Southern Asia, Pakistan, India, Bangladesh
Plant Part UsedFlower
ExtractEtOAc and MeOH
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin Sulphate (2.5 µg/ml), Isoniazid (0.06 µg/ml), Rifampin (0.004 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml50 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedDihydromonospermoside
PubChem IDNR
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19336944
Extract PreparationThe dried flowers (15.0 kg) were milled and soaked successively with n - hexane, EtOAc and MeOH. The hexane, EtOAc and MeOH extracts were evaporated under reduced pressure to give the crude hexane extract (brownish syrup, 32.8 g), the EtOAc extract (dark brownish sticky solid, 102.7 g) and the MeOH extract (dark brownish sticky solid, 527.6 g)
Chemical Classification [Active Compound]Aromatic, Chalcone, Ketone, Ether, Phenol, Sugar
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]NR
Molecular Weight436.137
Molecular FormulaC21H24O10
SMILES[C@@H]1([C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)Oc1c(ccc(c1)CCC(=O)c1ccc(cc1O)O)O
XLogP0.230
PSA177.140
H-bond Donor7
H-bond Acceptor10
No. of Rotatable Bond Count7
No. of Rings3
No. of N0
No. of O10
No. of S0
Reference(s)1) Chokchaisiri R, Suaisom C, Sriphota S, Chindaduang A, Chuprajob T, Suksamrarn A.Bioactive flavonoids of the flowers of Butea monosperma.Chem Pharm Bull (Tokyo). 2009 Apr;57(4):428-32

CuratorVikramjitmandal, Keyamukherjee, najiya-beegum, swatigandhi

                  Record - 8 of 12   [TOP]
Compound ID3947
Compound Structure
DOWNLOAD:
Plant SourceButea monosperma (LAM.) TAUB.     Common Name:Flame of the Forest
Source FamilyFabaceae
OriginTropical Southern Asia, Pakistan, India, Bangladesh
Plant Part UsedFlower
ExtractEtOAc and MeOH
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin Sulphate (2.5 µg/ml), Isoniazid (0.06 µg/ml), Rifampin (0.004 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml25 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedIsoliquiritigenin
PubChem ID   638278
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19336944
Extract PreparationThe dried flowers (15.0 kg) were milled and soaked successively with n - hexane, EtOAc and MeOH. The hexane, EtOAc and MeOH extracts were evaporated under reduced pressure to give the crude hexane extract (brownish syrup, 32.8 g), the EtOAc extract (dark brownish sticky solid, 102.7 g) and the MeOH extract (dark brownish sticky solid, 527.6 g)
Chemical Classification [Active Compound]Aromatic, Alkene, Chalcone, Phenol
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]NR
Molecular Weight256.074
Molecular FormulaC15H12O4
SMILESOc1c(C(=O)/C=C/c2ccc(O)cc2)ccc(O)c1
XLogP2.764
PSA77.760
H-bond Donor3
H-bond Acceptor4
No. of Rotatable Bond Count3
No. of Rings2
No. of N0
No. of O4
No. of S0
Reference(s)1) Chokchaisiri R, Suaisom C, Sriphota S, Chindaduang A, Chuprajob T, Suksamrarn A.Bioactive flavonoids of the flowers of Butea monosperma.Chem Pharm Bull (Tokyo). 2009 Apr;57(4):428-32

CuratorVikramjitmandal, Keyamukherjee, najiya-beegum, swatigandhi

                  Record - 9 of 12   [TOP]
Compound ID3948
Compound Structure
DOWNLOAD:
Plant SourceButea monosperma (LAM.) TAUB.     Common Name:Flame of the Forest
Source FamilyFabaceae
OriginTropical Southern Asia, Pakistan, India, Bangladesh
Plant Part UsedFlower
ExtractEtOAc and MeOH
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin Sulphate (2.5 µg/ml), Isoniazid (0.06 µg/ml), Rifampin (0.004 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml25 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound Identified(-)- Liquiritigenin
PubChem ID   114829
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19336944
Extract PreparationThe dried flowers (15.0 kg) were milled and soaked successively with n - hexane, EtOAc and MeOH. The hexane, EtOAc and MeOH extracts were evaporated under reduced pressure to give the crude hexane extract (brownish syrup, 32.8 g), the EtOAc extract (dark brownish sticky solid, 102.7 g) and the MeOH extract (dark brownish sticky solid, 527.6 g)
Chemical Classification [Active Compound]Aromatic, Tricyclic, Flavonoid, Phenol
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]NR
Molecular Weight256.074
Molecular FormulaC15H12O4
SMILESO1[C@@H](CC(=O)c2c1cc(O)cc2)c1ccc(O)cc1
XLogP1.860
PSA66.760
H-bond Donor2
H-bond Acceptor4
No. of Rotatable Bond Count1
No. of Rings3
No. of N0
No. of O4
No. of S0
Reference(s)1) Chokchaisiri R, Suaisom C, Sriphota S, Chindaduang A, Chuprajob T, Suksamrarn A.Bioactive flavonoids of the flowers of Butea monosperma.Chem Pharm Bull (Tokyo). 2009 Apr;57(4):428-32

CuratorVikramjitmandal, Keyamukherjee, najiya-beegum, swatigandhi

                  Record - 10 of 12   [TOP]
Compound ID3949
Compound Structure
DOWNLOAD:
Plant SourceButea monosperma (LAM.) TAUB.     Common Name:Flame of the Forest
Source FamilyFabaceae
OriginTropical Southern Asia, Pakistan, India, Bangladesh
Plant Part UsedFlower
ExtractEtOAc and MeOH
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin Sulphate (2.5 µg/ml), Isoniazid (0.06 µg/ml), Rifampin (0.004 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml50 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedFormononetin
PubChem ID   5280378
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19336944
Extract PreparationThe dried flowers (15.0 kg) were milled and soaked successively with n - hexane, EtOAc and MeOH. The hexane, EtOAc and MeOH extracts were evaporated under reduced pressure to give the crude hexane extract (brownish syrup, 32.8 g), the EtOAc extract (dark brownish sticky solid, 102.7 g) and the MeOH extract (dark brownish sticky solid, 527.6 g)
Chemical Classification [Active Compound]Aromatic, Tricyclic, Flavonoid, Ether, Phenol
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]NR
Molecular Weight268.074
Molecular FormulaC16H12O4
SMILESO1c2c(c(=O)c(c3ccc(OC)cc3)c1)ccc(O)c2
XLogP2.707
PSA46.530
H-bond Donor1
H-bond Acceptor3
No. of Rotatable Bond Count2
No. of Rings3
No. of N0
No. of O4
No. of S0
Reference(s)1) Chokchaisiri R, Suaisom C, Sriphota S, Chindaduang A, Chuprajob T, Suksamrarn A.Bioactive flavonoids of the flowers of Butea monosperma.Chem Pharm Bull (Tokyo). 2009 Apr;57(4):428-32

CuratorVikramjitmandal, Keyamukherjee, najiya-beegum, swatigandhi

                  Record - 11 of 12   [TOP]
Compound ID3950
Compound Structure
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Plant SourceButea monosperma (LAM.) TAUB.     Common Name:Flame of the Forest
Source FamilyFabaceae
OriginTropical Southern Asia, Pakistan, India, Bangladesh
Plant Part UsedFlower
ExtractEtOAc and MeOH
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin Sulphate (2.5 µg/ml), Isoniazid (0.06 µg/ml), Rifampin (0.004 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml25 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedAfrormosin
PubChem ID   5281704
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19336944
Extract PreparationThe dried flowers (15.0 kg) were milled and soaked successively with n - hexane, EtOAc and MeOH. The hexane, EtOAc and MeOH extracts were evaporated under reduced pressure to give the crude hexane extract (brownish syrup, 32.8 g), the EtOAc extract (dark brownish sticky solid, 102.7 g) and the MeOH extract (dark brownish sticky solid, 527.6 g)
Chemical Classification [Active Compound]Aromatic, Tricyclic, Flavonoid, Ether, Phenol
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]NR
Molecular Weight298.084
Molecular FormulaC17H14O5
SMILESO1c2c(c(=O)c(c3ccc(OC)cc3)c1)cc(OC)c(O)c2
XLogP2.263
PSA55.760
H-bond Donor1
H-bond Acceptor4
No. of Rotatable Bond Count3
No. of Rings3
No. of N0
No. of O5
No. of S0
Reference(s)1) Chokchaisiri R, Suaisom C, Sriphota S, Chindaduang A, Chuprajob T, Suksamrarn A.Bioactive flavonoids of the flowers of Butea monosperma.Chem Pharm Bull (Tokyo). 2009 Apr;57(4):428-32

CuratorVikramjitmandal, Keyamukherjee, najiya-beegum, swatigandhi

                  Record - 12 of 12   [TOP]
Compound ID3951
Compound Structure
DOWNLOAD:
Plant SourceButea monosperma (LAM.) TAUB.     Common Name:Flame of the Forest
Source FamilyFabaceae
OriginTropical Southern Asia, Pakistan, India, Bangladesh
Plant Part UsedFlower
ExtractEtOAc and MeOH
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Kanamycin Sulphate (2.5 µg/ml), Isoniazid (0.06 µg/ml), Rifampin (0.004 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml100 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedFormononetin - 7 - O - β - D - Glucopyranoside
PubChem ID   442813
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19336944
Extract PreparationThe dried flowers (15.0 kg) were milled and soaked successively with n - hexane, EtOAc and MeOH. The hexane, EtOAc and MeOH extracts were evaporated under reduced pressure to give the crude hexane extract (brownish syrup, 32.8 g), the EtOAc extract (dark brownish sticky solid, 102.7 g) and the MeOH extract (dark brownish sticky solid, 527.6 g)
Chemical Classification [Active Compound]Aromatic, Tricyclic, Flavonoid, Ether, Sugar
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]NR
Molecular Weight430.126
Molecular FormulaC22H22O9
SMILESO1[C@@H]([C@@H](O)[C@H](O)[C@@H](O)[C@@H]1Oc1cc2occ(c(=O)c2cc1)c1ccc(OC)cc1)CO
XLogP1.599
PSA125.680
H-bond Donor4
H-bond Acceptor8
No. of Rotatable Bond Count5
No. of Rings4
No. of N0
No. of O9
No. of S0
Reference(s)1) Chokchaisiri R, Suaisom C, Sriphota S, Chindaduang A, Chuprajob T, Suksamrarn A.Bioactive flavonoids of the flowers of Butea monosperma.Chem Pharm Bull (Tokyo). 2009 Apr;57(4):428-32

CuratorVikramjitmandal, Keyamukherjee, najiya-beegum, swatigandhi


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