BioPhytMol: A database of Phytomolecules against Mycobacteria

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Page - 1 of 7 Record - 1 of 174 [TOP]

Compound ID	1036
Compound Structure
Plant Source	Achyranthus aspera Linn. Common Name:Prickly Chaff Flower (English), Apaamaarga (Sanskrit)
Source Family	Amaranthaceae
Origin	India
Plant Part Used	Fruit, whole plant
Extract	Methanol
Target Bacteria	Mycobacterium avium
Assay / Test Done	Micro Broth Dilution Method
Positive Control Used (conc.)	Streptomycin (IC50 value 1.14)
Inhibition [%]
Activity [MIC] µg/ml	> 500 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, bronchitis, expectorant, asthma, cough, pulmonary infections, skin diseases
PubMed ID [Source Literature]	11744296
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
Curator

Record - 2 of 174 [TOP]

Compound ID	1037
Compound Structure
Plant Source	Achyranthus aspera Linn. Common Name:Prickly Chaff Flower (English), Apaamaarga (Sanskrit)
Source Family	Amaranthaceae
Origin	India
Plant Part Used	Fruit, whole plant
Extract	Methanol
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Micro Broth Dilution Method
Positive Control Used (conc.)	Streptomycin (IC50 value 0.17)
Inhibition [%]
Activity [MIC] µg/ml	> 500 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, bronchitis, expectorant, asthma, cough, pulmonary infections, skin diseases
PubMed ID [Source Literature]	11744296
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
Curator

Record - 3 of 174 [TOP]

Compound ID	1079
Compound Structure
Plant Source	Ageratum conyzoides L. Common Name:Ageratum, Billy Goat Weed, Blue Flowered Groundsel, Blue Top (English)
Source Family	Asteraceae (Compositae)
Origin	Malaysia
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv
Assay / Test Done	Colorimetric Tetrazolium Microplate Assay (TEMA)
Positive Control Used (conc.)	Isoniazid (0.078 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	1600 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cough
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Anonymous, 2010a. Traditional Malay Poisons, Available at: http://www.prn.usm.my/old website/mainsite/plant/plant.html (accessed 30.20.09) 2) http://www.ars-grin.gov/cgi-bin/npgs/html/taxon.pl?103793
Curator

Record - 4 of 174 [TOP]

Compound ID	1081
Compound Structure
Plant Source	Agrimonia eupatoria L. Common Name:Agrimony, Stickle Wort (English)
Source Family	Rosaceae
Origin	India
Plant Part Used	Whole plant
Extract	Chloroform
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Agar - Dilution Test
Positive Control Used (conc.)	Gentamicin (0.01 g/ml)
Inhibition [%]
Activity [MIC] µg/ml	100000 µg of dried plant/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	General infectious diseases, antiseptic, disinfectant, cough
PubMed ID [Source Literature]	3325696
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Ríos JL, Recio MC, Villar A.Antimicrobial activity of selected plants employed in the Spanish Mediterranean area.J Ethnopharmacol. 1987 Nov;21(2):139-52
Curator

Record - 5 of 174 [TOP]

Compound ID	1160
Compound Structure
Plant Source	Amaranthus tricolor L. Common Name:Josephs Coat Amaranth (English)
Source Family	Amaranthaceae
Origin	Malaysia
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv
Assay / Test Done	Colorimetric Tetrazolium Microplate Assay (TEMA)
Positive Control Used (conc.)	Isoniazid (0.078 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	1600 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cough
PubMed ID [Source Literature]	21094237
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Mohamad S, Zin NM, Wahab HA, Ibrahim P, Sulaiman SF, Zahariluddin AS, Noor SS.Antituberculosis potential of some ethnobotanically selected Malaysian plants.J Ethnopharmacol. 2011 Feb 16;133(3):1021-6
Curator

Record - 6 of 174 [TOP]

Compound ID	1215
Compound Structure
Plant Source	Artemisia scoparia Waldst. & Kit Common Name:Red Stem Wormwood (English)
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Whole plant
Extract	Ethanol (80 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Agar Dilution - Streak Assay
Positive Control Used (conc.)
Inhibition [%]	Partial
Activity [MIC] µg/ml	1563 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Earache, purgative, used in herbal medicine for diseases
PubMed ID [Source Literature]	541687
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Al-Shamma A, Mitscher LA.Comprehensive survey of indigenous Iraqi plants for potential economic value. 1. Screening results of 327 species for alkaloids and antimicrobial agents.J Nat Prod. 1979 Nov-Dec;42(6):633-42 2) Sudhanshu Kumar Jain.Dictionary of Indian Folk Medicine and Ethnobotany:A Reference Manual of Man-Plant Relationships, Ethnic Groups & Ethnobotanists in India.Deep Publications, 1991 - 311 pages
Curator

Record - 7 of 174 [TOP]

Compound ID	1249
Compound Structure
Plant Source	Berberis vulgaris L. Common Name:Common Barberry, True Barberry (English), Daruharidraa (Sanskrit)
Source Family	Berberidaceae
Origin	India
Plant Part Used	Whole plant
Extract	Chloroform
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Agar - Dilution Test
Positive Control Used (conc.)	Gentamicin (0.01 mg/ml)
Inhibition [%]
Activity [MIC] µg/ml	100000 µg dried plant/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	General infectious diseases, antiseptic, disinfectant
PubMed ID [Source Literature]	3325696
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Ríos JL, Recio MC, Villar A.Antimicrobial activity of selected plants employed in the Spanish Mediterranean area.J Ethnopharmacol. 1987 Nov;21(2):139-52
Curator

Record - 8 of 174 [TOP]

Compound ID	1294
Compound Structure
Plant Source	Bromus scoparius L. syn. Bromus rubens Cav. Common Name:Red Brome (English)
Source Family	Poaceae
Origin	India
Plant Part Used	Whole plant
Extract	Whole plant juice
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	The allied species B. mollis L. for giddiness in man and animals
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 9 of 174 [TOP]

Compound ID	1310
Compound Structure
Plant Source	Buxus papillosa C. K. syn. Buxus sempervirens L. Common Name:Himalayan Boxwood Tree (English)
Source Family	Buxaceae
Origin	India
Plant Part Used	Whole plant
Extract	Ethanol (95 %)
Target Bacteria	Mycobacterium smegmatis, Mycobacterium phlei
Assay / Test Done	Agar - Well Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	13 - 18 mm at 50 µl of extract
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Combs, pain, headache, stomatitis, febrifuge, syphilis, rheumatism, diaphoretic, random screening
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 14. Lalit Mohan Basu, Allahabad, India
Curator

Record - 10 of 174 [TOP]

Compound ID	1368
Compound Structure
Plant Source	Capsella bursa-pastoris (L.) Moench Common Name:Shepherd's Purse (English)
Source Family	Brassicaceae
Origin	India
Plant Part Used	Whole plant
Extract	Chloroform
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Agar - Dilution Test
Positive Control Used (conc.)	Gentamicin (0.01 mg/ml)
Inhibition [%]
Activity [MIC] µg/ml	77000 µg dried plant/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	General infectious diseases, antiseptic, disinfectant
PubMed ID [Source Literature]	3325696
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Ríos JL, Recio MC, Villar A.Antimicrobial activity of selected plants employed in the Spanish Mediterranean area.J Ethnopharmacol. 1987 Nov;21(2):139-52
Curator

Record - 11 of 174 [TOP]

Compound ID	1409
Compound Structure
Plant Source	Centella asiatica (L.) Urban Common Name:Asiatic Pennywort, Indian Pennywort (English), Mandukaparni, Mandukaparnikaa (Sanskrit)
Source Family	Apiaceae (Umbelliferae)
Origin	Malaysia, India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv
Assay / Test Done	Colorimetric Tetrazolium Microplate Assay (TEMA)
Positive Control Used (conc.)	Isoniazid (0.078 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	1600 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Asthma, treatment of leprosy and skin diseases
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Anonymous, 2010d. Mai-herbs and their Benefits (Available at: http://mai-cafe.com/pmaiherbs.php (accessed 21.03.10)) 2) http://www.himalayahealthcare.com/herbfinder/h_centel.htm
Curator

Record - 12 of 174 [TOP]

Compound ID	1410
Compound Structure
Plant Source	Centella asiatica (L.) Urban Common Name:Asiatic Pennywort, Indian Pennywort (English), Mandukaparni, Mandukaparnikaa (Sanskrit)
Source Family	Apiaceae (Umbelliferae)
Origin	Malaysia, India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium avium
Assay / Test Done	Micro Broth Dilution Method
Positive Control Used (conc.)	Streptomycin (IC50 value 1.14)
Inhibition [%]
Activity [MIC] µg/ml	> 500 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Asthma, treatment of leprosy and skin diseases
PubMed ID [Source Literature]	11744296
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67 2) http://www.himalayahealthcare.com/herbfinder/h_centel.htm
Curator

Record - 13 of 174 [TOP]

Compound ID	1411
Compound Structure
Plant Source	Centella asiatica (L.) Urban Common Name:Asiatic Pennywort, Indian Pennywort (English), Mandukaparni, Mandukaparnikaa (Sanskrit)
Source Family	Apiaceae (Umbelliferae)
Origin	Malaysia, India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Micro Broth Dilution Method
Positive Control Used (conc.)	Streptomycin (IC50 value 0.17)
Inhibition [%]
Activity [MIC] µg/ml	> 500 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Asthma, treatment of leprosy and skin diseases
PubMed ID [Source Literature]	11744296
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67 2) http://www.himalayahealthcare.com/herbfinder/h_centel.htm
Curator

Record - 14 of 174 [TOP]

Compound ID	1421
Compound Structure
Plant Source	Ceratophyllum demersum L. Common Name:Coontail, Hornwort (English), Shaivaala (Sanskrit)
Source Family	Ceratophyllaceae
Origin	India
Plant Part Used	Whole plant
Extract	Ethanol (80 %), petroleum ether
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	1000000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Laxative, antipyretic, ulcers, cooling, biliousness, diseases of blood, scorpion - sting
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 14. Lalit Mohan Basu, Allahabad, India
Curator

Record - 15 of 174 [TOP]

Compound ID	1431
Compound Structure
Plant Source	Chamaesyce hirta (L.) Millspaugh Common Name:Asthma plant, Garden Spurge, Hairy Spurge, Pill - Bearing Spurge, Pill - Pod Broomspurge, Pill - Pod Sandmat, Pillpod Sandmat, Spurge/Chara
Source Family	Euphorbiaceae
Origin	Peru
Plant Part Used	Whole plant
Extract	Dichloromethane
Target Bacteria	Mycobacterium tuberculosis (ATCC 27294)
Assay / Test Done	BACTEC 460 (Becton Dickinson Diagnostic Instrument Systems, Sparks MD) Radiometric Assay
Positive Control Used (conc.)	Rifampin (2 µg/ml), Ethambutol (7.5 µg/ml)
Inhibition [%]	55 %
Activity [MIC] µg/ml	50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]	13678239
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Graham JG, Pendland SL, Prause JL, Danzinger LH, Schunke Vigo J, Cabieses F, Farnsworth NR.Antimycobacterial evaluation of Peruvian plants.Phytomedicine. 2003;10(6-7):528-35
Curator

Record - 16 of 174 [TOP]

Compound ID	1454
Compound Structure
Plant Source	Cirsium arvense (L.) Scop. Common Name:Creeping Thistle, Canada Thistle (English)
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Whole plant
Extract	Ethanol (95 %)
Target Bacteria	Mycobacterium phlei, Mycobacterium smegmatis
Assay / Test Done
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Emetic, diuretic, tonic, diaphoretic, emmenagogue
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Frisbey A, Roberts J, Jennings J, Gottshall R, Lucas E (1953) The occurrence of antibacterial substances in seed plants with special reference to Mycobacterium tuberculosis (Third Report). Michigan State College of Agriculture and Applied Science Quarterly Bulletin 35: 392-404 2) Anonymous, 1986. The Useful Plants of India. Council of Scientific and Industrial Research, New Delhi, India
Curator

Record - 17 of 174 [TOP]

Compound ID	1494
Compound Structure
Plant Source	Clitoria ternatea L. Common Name:Butterfly Pea (English)
Source Family	Fabaceae
Origin	Malaysia
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv
Assay / Test Done	Colorimetric Tetrazolium Microplate Assay (TEMA)
Positive Control Used (conc.)	Isoniazid (0.078 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	1600 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cough
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Salleh, 1998. List of Malaysian medicinal plants with both cultivation and conservation (IDS Project Report: Biotechnology Application in Sabah) (Available at: http://www.borneofocus.com/saip/vaic/R&D/article5.htm)
Curator

Record - 18 of 174 [TOP]

Compound ID	1508
Compound Structure
Plant Source	Colebrookea oppositifolia Smith Common Name:Indian Squirrel Tail (English)
Source Family	Lamiaceae
Origin	India
Plant Part Used	Whole plant
Extract	Ethanol
Target Bacteria	Mycobacterium smegmatis (MTCC 6), Mycobacterium smegmatis (MTCC 995)
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Rifampin (5.0 µg/Disc)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	17.3 ± 1.5 mm and 17 ± 0.0 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Wound, epilepsy
PubMed ID [Source Literature]	21114505
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta VK, Shukla C, Bisht GR, Saikia D, Kumar S, Thakur RL.Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay.Lett Appl Microbiol. 2011 Jan;52(1):33-40 2) http://www.flowersofIndia.net/catalog/slides/Indian%20Squirrel%20Tail.html
Curator

Record - 19 of 174 [TOP]

Compound ID	1541
Compound Structure
Plant Source	Corydalis rutaefolia Sibth. syn. Corydalis longipes D.Don · Prodr. Common Name:
Source Family	Papaveraceae
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml of dried plant material
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Typhoid fever
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 20 of 174 [TOP]

Compound ID	1603
Compound Structure
Plant Source	Didymocarpus subalternans Wall. syn. Didymocarpus primulifolia Don Prodr. Common Name:
Source Family	Gesneriaceae
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml of dried plant
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Flu
PubMed ID [Source Literature]	7564413
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Manandhar NP, Towers GH.Screening of selected medicinal plants of Nepal for antimicrobial activities.J Ethnopharmacol. 1995 Jun;46(3):153-9
Curator

Record - 21 of 174 [TOP]

Compound ID	1611
Compound Structure
Plant Source	Dittrichia graveolens L. Common Name:Stinkwort
Source Family	Asteraceae (Compositae)
Origin	Africa
Plant Part Used	Whole plant
Extract	Acetone:water (4:1)
Target Bacteria	Mycobacterium aurum
Assay / Test Done	Bioautography on TLC plates
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]	18384988
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Bamuamba K, Gammon DW, Meyers P, Dijoux-Franca MG, Scott G.Anti-mycobacterial activity of five plant species used as traditional medicines in the Western Cape Province (South Africa).J Ethnopharmacol. 2008 May 8;117(2):385-90 2) http://plants.usda.gov/java/profile?symbol=DIGR3
Curator

Record - 22 of 174 [TOP]

Compound ID	1618
Compound Structure
Plant Source	Drymaria cordata Willd. Common Name:Whitesnow (English)
Source Family	Caryophyllaceae
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml of dried plant
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Asthma, cough, cold
PubMed ID [Source Literature]	7564413
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Manandhar NP, Towers GH.Screening of selected medicinal plants of Nepal for antimicrobial activities.J Ethnopharmacol. 1995 Jun;46(3):153-9
Curator

Record - 23 of 174 [TOP]

Compound ID	1622
Compound Structure
Plant Source	Egletes viscosa (L.) Lessing Common Name:Macela
Source Family	Asteraceae (Compositae)
Origin	Peru
Plant Part Used	Whole plant
Extract	Dichloromethane
Target Bacteria	Mycobacterium tuberculosis (ATCC 27294)
Assay / Test Done	BACTEC 460 (Becton Dickinson Diagnostic Instrument Systems, Sparks MD) Radiometric Assay
Positive Control Used (conc.)	Rifampin (2 µg/ml), Ethambutol (7.5 µg/ml)
Inhibition [%]	54 %
Activity [MIC] µg/ml	50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]	13678239
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Graham JG, Pendland SL, Prause JL, Danzinger LH, Schunke Vigo J, Cabieses F, Farnsworth NR.Antimycobacterial evaluation of Peruvian plants.Phytomedicine. 2003;10(6-7):528-35
Curator

Record - 24 of 174 [TOP]

Compound ID	1625
Compound Structure
Plant Source	Elephantopus scaber L. Common Name:Mayura Shikhaa, Gojihvaa (Sanskrit)
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml of dried plant
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Bronchitis, cough, cold
PubMed ID [Source Literature]	7564413
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Manandhar NP, Towers GH.Screening of selected medicinal plants of Nepal for antimicrobial activities.J Ethnopharmacol. 1995 Jun;46(3):153-9 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India
Curator

Record - 25 of 174 [TOP]

Compound ID	1713
Compound Structure
Plant Source	Euphorbia heterophylla L. Common Name:
Source Family	Euphorbiaceae
Origin	Peru
Plant Part Used	Whole plant
Extract	Dichloromethane
Target Bacteria	Mycobacterium tuberculosis (ATCC 27294)
Assay / Test Done	BACTEC 460 (Becton Dickinson Diagnostic Instrument Systems, Sparks MD) Radiometric Assay
Positive Control Used (conc.)	Rifampin (2 µg/ml), Ethambutol (7.5 µg/ml)
Inhibition [%]	< 50 %
Activity [MIC] µg/ml	50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]	13678239
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Graham JG, Pendland SL, Prause JL, Danzinger LH, Schunke Vigo J, Cabieses F, Farnsworth NR.Antimycobacterial evaluation of Peruvian plants.Phytomedicine. 2003;10(6-7):528-35
Curator

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