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                  Page - 1 of 1                  Record - 1 of 11   [TOP]
Compound ID1354
Compound Structure
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Plant SourceCanscora decussata Schult.     Common Name:Daakuni, Sankhaapushpi, Dandotpala (Sanskrit)
Source FamilyGentaniaceae
OriginIndia
Plant Part UsedMother tinture
ExtractEthanol
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneTube Dilution Test
Positive Control Used (conc.)Streptomycin sulphate (0.5 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml200 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedMangiferin
PubChem ID   5281647
Ethnomedicinal InformationTuberculosis, leprosy
PubMed ID [Source Literature]807707, 565403
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Xanthonoid, Phenol, Sugar
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight422.085
Molecular FormulaC19H18O11
SMILESO1[C@H]([C@H](O)[C@@H](O)[C@H](O)[C@H]1CO)c1c(O)c2c(oc3c(c2=O)cc(O)c(O)c3)cc1O
XLogP-2.646
PSA188.140
H-bond Donor8
H-bond Acceptor10
No. of Rotatable Bond Count2
No. of Rings4
No. of N0
No. of O11
No. of S0
Reference(s)1) Ghosal S, Chaudhuri RK.Chemical constituents of Gentianaceae XVI: antitubercular activity of xanthones of Canscora decussata Schult.J Pharm Sci. 1975 May;64(5):888-9

2) Ghosal S, Biswas K, Chaudhuri RK.Chemical constituents of Gentianaceae XXIV: Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs.J Pharm Sci. 1978 May;67(5):721-2.

Curator

                  Record - 2 of 11   [TOP]
Compound ID1355
Compound Structure
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Plant SourceCanscora decussata Schult.     Common Name:Daakuni, Sankhaapushpi, Dandotpala (Sanskrit)
Source FamilyGentaniaceae
OriginIndia
Plant Part UsedMother tinture
ExtractEthanol
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneTube Dilution Test
Positive Control Used (conc.)Streptomycin sulphate (0.5 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml10 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified1,3,5-Trihydroxyxanthone
PubChem ID   25200626
Ethnomedicinal InformationTuberculosis, leprosy
PubMed ID [Source Literature]807707, 565403
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Xanthonoid, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight243.029
Molecular FormulaC13H7O5
SMILESO1c2c(c(=O)c3c1c([O-])ccc3)c(O)cc(O)c2
XLogP0.296
PSA80.590
H-bond Donor2
H-bond Acceptor3
No. of Rotatable Bond Count0
No. of Rings3
No. of N0
No. of O5
No. of S0
Reference(s)1) Ghosal S, Chaudhuri RK.Chemical constituents of Gentianaceae XVI: antitubercular activity of xanthones of Canscora decussata Schult.J Pharm Sci. 1975 May;64(5):888-9

2) Ghosal S, Biswas K, Chaudhuri RK.Chemical constituents of Gentianaceae XXIV: Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs.J Pharm Sci. 1978 May;67(5):721-2.

Curator

                  Record - 3 of 11   [TOP]
Compound ID1356
Compound Structure
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Plant SourceCanscora decussata Schult.     Common Name:Daakuni, Sankhaapushpi, Dandotpala (Sanskrit)
Source FamilyGentaniaceae
OriginIndia
Plant Part UsedMother tinture
ExtractEthanol
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneTube Dilution Test
Positive Control Used (conc.)Streptomycin sulphate (0.5 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml10 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified1, 3 - Dihydroxy - 5 - Methoxy - 9H - Xanthen - 9 - One
PubChem ID   12026489
Ethnomedicinal InformationTuberculosis, leprosy
PubMed ID [Source Literature]807707, 565403
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Xanthonoid, Ether, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight258.053
Molecular FormulaC14H10O5
SMILESO1c2c(c(=O)c3c1cc(O)cc3O)cccc2OC
XLogP0.815
PSA66.760
H-bond Donor2
H-bond Acceptor4
No. of Rotatable Bond Count1
No. of Rings3
No. of N0
No. of O5
No. of S0
Reference(s)1) Ghosal S, Chaudhuri RK.Chemical constituents of Gentianaceae XVI: antitubercular activity of xanthones of Canscora decussata Schult.J Pharm Sci. 1975 May;64(5):888-9

2) Ghosal S, Biswas K, Chaudhuri RK.Chemical constituents of Gentianaceae XXIV: Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs.J Pharm Sci. 1978 May;67(5):721-2.

Curator

                  Record - 4 of 11   [TOP]
Compound ID1357
Compound Structure
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Plant SourceCanscora decussata Schult.     Common Name:Daakuni, Sankhaapushpi, Dandotpala (Sanskrit)
Source FamilyGentaniaceae
OriginIndia
Plant Part UsedMother tinture
ExtractEthanol
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneTube Dilution Test
Positive Control Used (conc.)Streptomycin sulphate (0.5 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml10 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified1 - Hydroxy - 3, 5 - Dimethoxyxanthen - 9 - One
PubChem ID   5479773
Ethnomedicinal InformationTuberculosis, leprosy
PubMed ID [Source Literature]807707, 565403
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Xanthonoid, Ether, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight272.068
Molecular FormulaC15H12O5
SMILESO1c2c(c(=O)c3c1c(OC)ccc3)c(O)cc(OC)c2
XLogP1.334
PSA55.760
H-bond Donor1
H-bond Acceptor4
No. of Rotatable Bond Count2
No. of Rings3
No. of N0
No. of O5
No. of S0
Reference(s)1) Ghosal S, Chaudhuri RK.Chemical constituents of Gentianaceae XVI: antitubercular activity of xanthones of Canscora decussata Schult.J Pharm Sci. 1975 May;64(5):888-9

2) Ghosal S, Biswas K, Chaudhuri RK.Chemical constituents of Gentianaceae XXIV: Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs.J Pharm Sci. 1978 May;67(5):721-2.

Curator

                  Record - 5 of 11   [TOP]
Compound ID1358
Compound Structure
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Plant SourceCanscora decussata Schult.     Common Name:Daakuni, Sankhaapushpi, Dandotpala (Sanskrit)
Source FamilyGentaniaceae
OriginIndia
Plant Part UsedMother tinture
ExtractEthanol
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneTube Dilution Test
Positive Control Used (conc.)Streptomycin sulphate (0.5 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml10 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified1, 3, 5, 6 - Tetrahydroxyxanthen - 9 - One
PubChem ID   5479774
Ethnomedicinal InformationTuberculosis, leprosy
PubMed ID [Source Literature]807707, 565403
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Xanthonoid, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight260.032
Molecular FormulaC13H8O6
SMILESO1c2c(c(=O)c3c1cc(O)cc3O)ccc(O)c2O
XLogP-0.238
PSA97.990
H-bond Donor4
H-bond Acceptor5
No. of Rotatable Bond Count0
No. of Rings3
No. of N0
No. of O6
No. of S0
Reference(s)1) Ghosal S, Chaudhuri RK.Chemical constituents of Gentianaceae XVI: antitubercular activity of xanthones of Canscora decussata Schult.J Pharm Sci. 1975 May;64(5):888-9

2) Ghosal S, Biswas K, Chaudhuri RK.Chemical constituents of Gentianaceae XXIV: Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs.J Pharm Sci. 1978 May;67(5):721-2

Curator

                  Record - 6 of 11   [TOP]
Compound ID1359
Compound Structure
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Plant SourceCanscora decussata Schult.     Common Name:Daakuni, Sankhaapushpi, Dandotpala (Sanskrit)
Source FamilyGentaniaceae
OriginIndia
Plant Part UsedMother tinture
ExtractEthanol
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneTube Dilution Test
Positive Control Used (conc.)Streptomycin sulphate (0.5 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml10 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified1, 3, 6 - Trihydroxy - 5 - Methoxyxanthen - 9 - One
PubChem ID   5493675
Ethnomedicinal InformationTuberculosis, leprosy
PubMed ID [Source Literature]807707, 565403
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Xanthonoid, Ether, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight274.048
Molecular FormulaC14H10O6
SMILESO1c2c(c(=O)c3c1cc(O)cc3O)ccc(O)c2OC
XLogP-0.148
PSA86.990
H-bond Donor3
H-bond Acceptor5
No. of Rotatable Bond Count1
No. of Rings3
No. of N0
No. of O6
No. of S0
Reference(s)1) Ghosal S, Chaudhuri RK.Chemical constituents of Gentianaceae XVI: antitubercular activity of xanthones of Canscora decussata Schult.J Pharm Sci. 1975 May;64(5):888-9

2) Ghosal S, Biswas K, Chaudhuri RK.Chemical constituents of Gentianaceae XXIV: Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs.J Pharm Sci. 1978 May;67(5):721-2

Curator

                  Record - 7 of 11   [TOP]
Compound ID1360
Compound Structure
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Plant SourceCanscora decussata Schult.     Common Name:Daakuni, Sankhaapushpi, Dandotpala (Sanskrit)
Source FamilyGentaniaceae
OriginIndia
Plant Part UsedMother tinture
ExtractEthanol
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneTube Dilution Test
Positive Control Used (conc.)Streptomycin sulphate (0.5 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml10 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified1, 3, 5 - Trihydroxy - 6 - Methoxyxanthen - 9 - One
PubChem ID   5479775
Ethnomedicinal InformationTuberculosis, leprosy
PubMed ID [Source Literature]807707, 565403
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Xanthonoid, Ether, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight274.048
Molecular FormulaC14H10O6
SMILESO1c2c(c(=O)c3c1cc(O)cc3O)ccc(OC)c2O
XLogP-0.148
PSA86.990
H-bond Donor3
H-bond Acceptor5
No. of Rotatable Bond Count1
No. of Rings3
No. of N0
No. of O6
No. of S0
Reference(s)1) Ghosal S, Chaudhuri RK.Chemical constituents of Gentianaceae XVI: antitubercular activity of xanthones of Canscora decussata Schult.J Pharm Sci. 1975 May;64(5):888-9

2) Ghosal S, Biswas K, Chaudhuri RK.Chemical constituents of Gentianaceae XXIV: Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs.J Pharm Sci. 1978 May;67(5):721-2

Curator

                  Record - 8 of 11   [TOP]
Compound ID1361
Compound Structure
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Plant SourceCanscora decussata Schult.     Common Name:Daakuni, Sankhaapushpi, Dandotpala (Sanskrit)
Source FamilyGentaniaceae
OriginIndia
Plant Part UsedMother tinture
ExtractEthanol
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneTube Dilution Test
Positive Control Used (conc.)Streptomycin sulphate (0.5 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml10 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified3, 5 - Dimethoxy - 1, 6 - Dihydroxyxanthone
PubChem ID   5281630
Ethnomedicinal InformationTuberculosis, leprosy
PubMed ID [Source Literature]807707, 565403
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Xanthonoid, Ether, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight288.063
Molecular FormulaC15H12O6
SMILESO1c2c(c(=O)c3c1cc(OC)cc3O)ccc(O)c2OC
XLogP0.371
PSA75.990
H-bond Donor2
H-bond Acceptor5
No. of Rotatable Bond Count2
No. of Rings3
No. of N0
No. of O6
No. of S0
Reference(s)1) Ghosal S, Chaudhuri RK.Chemical constituents of Gentianaceae XVI: antitubercular activity of xanthones of Canscora decussata Schult.J Pharm Sci. 1975 May;64(5):888-9

2) Ghosal S, Biswas K, Chaudhuri RK.Chemical constituents of Gentianaceae XXIV: Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs.J Pharm Sci. 1978 May;67(5):721-2

Curator

                  Record - 9 of 11   [TOP]
Compound ID1362
Compound Structure
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Plant SourceCanscora decussata Schult.     Common Name:Daakuni, Sankhaapushpi, Dandotpala (Sanskrit)
Source FamilyGentaniaceae
OriginIndia
Plant Part UsedMother tinture
ExtractEthanol
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneTube Dilution Test
Positive Control Used (conc.)Streptomycin sulphate (0.5 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml10 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified1, 3, 5, 6, 7 - Pentahydroxyxanthen - 9 - One
PubChem ID   10333643
Ethnomedicinal InformationTuberculosis, leprosy
PubMed ID [Source Literature]807707, 565403
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Xanthonoid, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight276.027
Molecular FormulaC13H8O7
SMILESO1c2c(c(=O)c3c1cc(O)cc3O)cc(O)c(O)c2O
XLogP-0.772
PSA118.220
H-bond Donor5
H-bond Acceptor6
No. of Rotatable Bond Count0
No. of Rings3
No. of N0
No. of O7
No. of S0
Reference(s)1) Ghosal S, Chaudhuri RK.Chemical constituents of Gentianaceae XVI: antitubercular activity of xanthones of Canscora decussata Schult.J Pharm Sci. 1975 May;64(5):888-9

2) Ghosal S, Biswas K, Chaudhuri RK.Chemical constituents of Gentianaceae XXIV: Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs.J Pharm Sci. 1978 May;67(5):721-2

Curator

                  Record - 10 of 11   [TOP]
Compound ID1363
Compound Structure
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Plant SourceCanscora decussata Schult.     Common Name:Daakuni, Sankhaapushpi, Dandotpala (Sanskrit)
Source FamilyGentaniaceae
OriginIndia
Plant Part UsedMother tinture
ExtractEthanol
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneTube Dilution Test
Positive Control Used (conc.)Streptomycin sulphate (0.5 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml10 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified1, 6, 7 - Trihydroxy - 3, 5 - Dimethoxyxanthen - 9 - One
PubChem ID   5479777
Ethnomedicinal InformationTuberculosis, leprosy
PubMed ID [Source Literature]807707, 565403
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Xanthonoid, Ether, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight304.058
Molecular FormulaC15H12O7
SMILESO1c2c(c(=O)c3c1cc(OC)cc3O)cc(O)c(O)c2OC
XLogP-0.163
PSA96.220
H-bond Donor3
H-bond Acceptor6
No. of Rotatable Bond Count2
No. of Rings3
No. of N0
No. of O7
No. of S0
Reference(s)1) Ghosal S, Chaudhuri RK.Chemical constituents of Gentianaceae XVI: antitubercular activity of xanthones of Canscora decussata Schult.J Pharm Sci. 1975 May;64(5):888-9

2) Ghosal S, Biswas K, Chaudhuri RK.Chemical constituents of Gentianaceae XXIV: Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs.J Pharm Sci. 1978 May;67(5):721-2

Curator

                  Record - 11 of 11   [TOP]
Compound ID1364
Compound Structure
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Plant SourceCanscora decussata Schult.     Common Name:Daakuni, Sankhaapushpi, Dandotpala (Sanskrit)
Source FamilyGentaniaceae
OriginIndia
Plant Part UsedMother tinture
ExtractEthanol
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneTube Dilution Test
Positive Control Used (conc.)Streptomycin sulphate (0.5 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml10 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified1, 7 - Dihydroxy - 3, 5, 6 - Trimethoxyxanthen - 9 - One
PubChem ID   5491588
Ethnomedicinal InformationTuberculosis, leprosy
PubMed ID [Source Literature]807707, 565403
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Xanthonoid, Ether, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight318.074
Molecular FormulaC16H14O7
SMILESO1c2c(c(=O)c3c1cc(OC)cc3O)cc(O)c(OC)c2OC
XLogP-0.073
PSA85.220
H-bond Donor2
H-bond Acceptor6
No. of Rotatable Bond Count3
No. of Rings3
No. of N0
No. of O7
No. of S0
Reference(s)1) Ghosal S, Chaudhuri RK.Chemical constituents of Gentianaceae XVI: antitubercular activity of xanthones of Canscora decussata Schult.J Pharm Sci. 1975 May;64(5):888-9

2) Ghosal S, Biswas K, Chaudhuri RK.Chemical constituents of Gentianaceae XXIV: Anti-Mycobacterium tuberculosis activity of naturally occurring xanthones and synthetic analogs.J Pharm Sci. 1978 May;67(5):721-2

Curator


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