BioPhytMol: A database of Phytomolecules against Mycobacteria

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Page - 1 of 1 Record - 1 of 9 [TOP]

Compound ID	1634
Compound Structure
Plant Source	Eremophila alternifolia R. Br. Common Name:Poverty Bush
Source Family	Myoporaceae
Origin	Australia
Plant Part Used	Leaf, stem
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	66000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	General sickness, pain, respiratory track infection
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 2 of 9 [TOP]

Compound ID	1635
Compound Structure
Plant Source	Eremophila alternifolia R. Br. Common Name:Poverty Bush
Source Family	Myoporaceae
Origin	Australia
Plant Part Used	Leaf, stem
Extract	Ethanol
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	33000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	General sickness, pain, respiratory track infection
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 3 of 9 [TOP]

Compound ID	1636
Compound Structure
Plant Source	Eremophila duttonii F.Muell. Common Name:Budda or Harlequin Fuchsia Bush
Source Family	Myoporaceae
Origin	Australia
Plant Part Used	Leaf, stem
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum, Mycobacterium smegmatis
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Respiratory tract infection, sore throat, skin cuts, painful ears, inflamed eyes
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 4 of 9 [TOP]

Compound ID	1637
Compound Structure
Plant Source	Eremophila latrobei F. Muell. Subsp. Glabra(L.S. Smith)Chinn. Common Name:Crimson Turkey Bush
Source Family	Myoporaceae
Origin	Australia
Plant Part Used	Leaf, stem
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum, Mycobacterium smegmatis
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Malaise, cough, respiratory track infection, sore throat
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 5 of 9 [TOP]

Compound ID	1638
Compound Structure
Plant Source	Eremophila longifolia (R.Br.) F.Muell. Common Name:Berrigan
Source Family	Myoporaceae
Origin	Australia
Plant Part Used	Stem
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	40000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Skin sores and boils, respiratory track infection, eye wash
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 6 of 9 [TOP]

Compound ID	1639
Compound Structure
Plant Source	Eremophila longifolia (R.Br.) F.Muell. Common Name:Berrigan
Source Family	Myoporaceae
Origin	Australia
Plant Part Used	Stem
Extract	Ethanol
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	20000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Skin sores and boils, respiratory track infection, eye wash
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 7 of 9 [TOP]

Compound ID	1640
Compound Structure
Plant Source	Eremophila sturtii R.Br. Common Name:Narrow Leaf Emu Bush, Turpentine Bush
Source Family	Myoporaceae
Origin	Australia
Plant Part Used	Leaf, stem
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum, Mycobacterium smegmatis
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cough, general sickness, skin cuts, sore eyes, respiratory infection
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 8 of 9 [TOP]

Compound ID	2217
Compound Structure
Plant Source	Myoporum crassifolium Common Name:
Source Family	Myoporaceae
Origin	Caledonia
Plant Part Used	Wood
Extract	Hexane
Target Bacteria	Mycobacterium bovis (BCG - Bacillus Calmette Guerin)
Assay / Test Done	96 - well Microplate Dilution Method
Positive Control Used (conc.)	Ethambutol (20 µg/ml), Pyrazynamide (2.5 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	100 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]	15588670
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Billo M, Cabalion P, Waikedre J, Fourneau C, Bouttier S, Hocquemiller R, Fournet A.Screening of some New Caledonian and Vanuatu medicinal plants for antimycobacterial activity.J Ethnopharmacol. 2005 Jan 4;96(1-2):195-200
Curator

Record - 9 of 9 [TOP]

Compound ID	2218
Compound Structure
Plant Source	Myoporum crassifolium Common Name:
Source Family	Myoporaceae
Origin	Caledonia
Plant Part Used	Wood
Extract	Essential oil
Target Bacteria	Mycobacterium bovis (BCG - Bacillus Calmette Guerin)
Assay / Test Done	96 - well Microplate Dilution Method
Positive Control Used (conc.)	Ethambutol (20 µg/ml), Pyrazynamide (2.5 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis
PubMed ID [Source Literature]	15588670
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Billo M, Cabalion P, Waikedre J, Fourneau C, Bouttier S, Hocquemiller R, Fournet A.Screening of some New Caledonian and Vanuatu medicinal plants for antimycobacterial activity.J Ethnopharmacol. 2005 Jan 4;96(1-2):195-200
Curator

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