| Compound ID | 1342 |
| Compound Structure | |
| Plant Source | Campomanesia lineatifolia R. & P. Common Name: |
| Source Family | Myrtaceae |
| Origin | Peru |
| Plant Part Used | Stem |
| Extract | Dichloromethane |
| Target Bacteria | Mycobacterium tuberculosis (ATCC 27294) |
| Assay / Test Done | BACTEC 460 (Becton Dickinson Diagnostic Instrument Systems, Sparks MD) Radiometric Assay |
| Positive Control Used (conc.) | Rifampin (2 µg/ml), Ethambutol (7.5 µg/ml) |
| Inhibition [%] | < 50 % |
| Activity [MIC] µg/ml | 50 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | 13678239 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Graham JG, Pendland SL, Prause JL, Danzinger LH, Schunke Vigo J, Cabieses F, Farnsworth NR.Antimycobacterial evaluation of Peruvian plants.Phytomedicine. 2003;10(6-7):528-35
|
| Curator | |
| Compound ID | 1658 |
| Compound Structure | |
| Plant Source | Eucalyptus botryoides Smith Common Name: |
| Source Family | Myrtaceae |
| Origin | Brazil |
| Plant Part Used | Leaf |
| Extract | Essential oil |
| Target Bacteria | MDR Mycobacterium tuberculosis and 8 other species |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 0.01 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Moreira, Raquel R. D; Anno, Ivone S; Leite, Clarice Q. F.Sensitivity of mycobacteria to different species of Eucalyptus L herit.Rev. microbiol;28(4):256-60
|
| Curator | |
| Compound ID | 1659 |
| Compound Structure | |
| Plant Source | Eucalyptus camaldulensis Dehnh Common Name: |
| Source Family | Myrtaceae |
| Origin | Brazil, Turkey |
| Plant Part Used | Leaf |
| Extract | Essential oil |
| Target Bacteria | MDR Mycobacterium tuberculosis and 8 other species |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | N/A |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | 15507348 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Tosun F, Kizilay CA, Sener B, Vural M, Palittapongarnpim P.Antimycobacterial screening of some Turkish plants.J Ethnopharmacol. 2004 Dec;95(2-3):273-5
|
| Curator | |
| Compound ID | 1660 |
| Compound Structure | |
| Plant Source | Eucalyptus camaldulensis Dehnh Common Name: |
| Source Family | Myrtaceae |
| Origin | Brazil, Turkey |
| Plant Part Used | Leaf |
| Extract | Ethanol (70 %) |
| Target Bacteria | Mycobacterium tuberculosis H37Ra |
| Assay / Test Done | Microplate Alamar Blue Assay (MABA) |
| Positive Control Used (conc.) | Rifampin (0.0047 – 0.0095 µg/ml), Isoniazid (0.05 – 0.1 µg/ml), Kanamycin (2.5 – 5.0 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | N/A |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | 15507348 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Tosun F, Kizilay CA, Sener B, Vural M, Palittapongarnpim P.Antimycobacterial screening of some Turkish plants.J Ethnopharmacol. 2004 Dec;95(2-3):273-5
|
| Curator | |
| Compound ID | 1661 |
| Compound Structure | |
| Plant Source | Eucalyptus citriodora hook Common Name: |
| Source Family | Myrtaceae |
| Origin | Brazil |
| Plant Part Used | Leaf |
| Extract | Essential oil |
| Target Bacteria | MDR Mycobacterium tuberculosis and 8 other species |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 0.005 except MK |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Moreira, Raquel R. D; Anno, Ivone S; Leite, Clarice Q. F.Sensitivity of mycobacteria to different species of Eucalyptus L herit.Rev. microbiol;28(4):256-60, out.-dez. 1997. graf.
|
| Curator | |
| Compound ID | 1662 |
| Compound Structure | |
| Plant Source | Eucalyptus deglupta Smith Common Name: |
| Source Family | Myrtaceae |
| Origin | Brazil |
| Plant Part Used | Leaf |
| Extract | Essential oil |
| Target Bacteria | MDR Mycobacterium tuberculosis and 8 other species |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 0.01 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Moreira, Raquel R. D; Anno, Ivone S; Leite, Clarice Q. F.Sensitivity of mycobacteria to different species of Eucalyptus L herit.Rev. microbiol;28(4):256-60
|
| Curator | |
| Compound ID | 1663 |
| Compound Structure | |
| Plant Source | Eucalyptus globulus Labill Common Name:Blue Gum Tree (English), Tilaparna, Tailaparna, Sugandhapatra (Sanskrit) |
| Source Family | Myrtaceae |
| Origin | Brazil, Tasmania, Australia, South Europe |
| Plant Part Used | Leaf |
| Extract | Essential oil |
| Target Bacteria | MDR Mycobacterium tuberculosis, Mycobacterium tuberculosis, Mycobacterium avium |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 0.01 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Antiseptic, expectorant, stimulant, febrifuge and used to treat cough, respiratory disorders |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Moreira, Raquel R. D; Anno, Ivone S; Leite, Clarice Q. F.Sensitivity of mycobacteria to different species of Eucalyptus L herit.Rev. microbiol;28(4):256-60
|
| Curator | |
| Compound ID | 1664 |
| Compound Structure | |
| Plant Source | Eucalyptus globulus Labill Common Name:Blue Gum Tree (English), Tilaparna, Tailaparna, Sugandhapatra (Sanskrit) |
| Source Family | Myrtaceae |
| Origin | Brazil, Tasmania, Australia, South Europe |
| Plant Part Used | Leaf |
| Extract | Ethanol |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Antiseptic, expectorant, stimulant, febrifuge and used to treat cough, respiratory disorders |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Moreira, Raquel R. D; Anno, Ivone S; Leite, Clarice Q. F.Sensitivity of mycobacteria to different species of Eucalyptus L herit.Rev. microbiol;28(4):256-60, out.-dez. 1997. graf.
|
| Curator | |
| Compound ID | 1665 |
| Compound Structure | |
| Plant Source | Eucalyptus globulus Labill Common Name:Blue Gum Tree (English), Tilaparna, Tailaparna, Sugandhapatra (Sanskrit) |
| Source Family | Myrtaceae |
| Origin | Brazil, Tasmania, Australia, South Europe |
| Plant Part Used | Leaf |
| Extract | Methanol (23.65 %) |
| Target Bacteria | Mycobacterium aurum |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Streptomycin (IC50 value 1.14) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Antiseptic, expectorant, stimulant, febrifuge and used to treat cough, respiratory disorders |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
|
| Curator | |
| Compound ID | 1666 |
| Compound Structure | |
| Plant Source | Eucalyptus globulus Labill Common Name:Blue Gum Tree (English), Tilaparna, Tailaparna, Sugandhapatra (Sanskrit) |
| Source Family | Myrtaceae |
| Origin | Brazil, Tasmania, Australia, South Europe |
| Plant Part Used | Leaf |
| Extract | Methanol (23.65 %) |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Streptomycin (IC50 value 0.17) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 500 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Antiseptic, expectorant, stimulant, febrifuge and used to treat cough, respiratory disorders |
| PubMed ID [Source Literature] | 11744296 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67
|
| Curator | |
| Compound ID | 1667 |
| Compound Structure | |
| Plant Source | Eucalyptus grandis Smith Common Name: |
| Source Family | Myrtaceae |
| Origin | Brazil |
| Plant Part Used | Leaf |
| Extract | Essential oil |
| Target Bacteria | MDR Mycobacterium tuberculosis and 8 other species |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 0.005 µg/ml except MA and MG |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Moreira, Raquel R. D; Anno, Ivone S; Leite, Clarice Q. F.Sensitivity of mycobacteria to different species of Eucalyptus L herit.Rev. microbiol;28(4):256-60, out.-dez. 1997. graf.
|
| Curator | |
| Compound ID | 1668 |
| Compound Structure | |
| Plant Source | Eucalyptus maculata Hook Common Name: |
| Source Family | Myrtaceae |
| Origin | Brazil |
| Plant Part Used | Leaf |
| Extract | Essential oil |
| Target Bacteria | MDR Mycobacterium tuberculosis and 8 other species |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 0.005 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Moreira, Raquel R. D; Anno, Ivone S; Leite, Clarice Q. F.Sensitivity of mycobacteria to different species of Eucalyptus L herit.Rev. microbiol;28(4):256-60, out.-dez. 1997. graf.
|
| Curator | |
| Compound ID | 1669 |
| Compound Structure | |
| Plant Source | Eucalyptus tereticornis Smith Common Name: |
| Source Family | Myrtaceae |
| Origin | Brazil |
| Plant Part Used | Leaf |
| Extract | Essential oil |
| Target Bacteria | MDR Mycobacterium tuberculosis and 8 other species |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 0.005 µg/ml except MK |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Moreira, Raquel R. D; Anno, Ivone S; Leite, Clarice Q. F.Sensitivity of mycobacteria to different species of Eucalyptus L herit.Rev. microbiol;28(4):256-60, out.-dez. 1997. graf.
|
| Curator | |
| Compound ID | 1708 |
| Compound Structure | |
| Plant Source | Eugenia egensis DC. Common Name: |
| Source Family | Myrtaceae |
| Origin | Peru |
| Plant Part Used | Stem |
| Extract | Dichloromethane |
| Target Bacteria | Mycobacterium tuberculosis (ATCC 27294) |
| Assay / Test Done | BACTEC 460 (Becton Dickinson Diagnostic Instrument Systems, Sparks MD) Radiometric Assay |
| Positive Control Used (conc.) | Rifampin (2 µg/ml), Ethambutol (7.5 µg/ml) |
| Inhibition [%] | < 50 % |
| Activity [MIC] µg/ml | 50 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | 13678239 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Graham JG, Pendland SL, Prause JL, Danzinger LH, Schunke Vigo J, Cabieses F, Farnsworth NR.Antimycobacterial evaluation of Peruvian plants.Phytomedicine. 2003;10(6-7):528-35
|
| Curator | |
| Compound ID | 1709 |
| Compound Structure | |
| Plant Source | Eugenia patens Poiret Common Name: |
| Source Family | Myrtaceae |
| Origin | Peru |
| Plant Part Used | Stem |
| Extract | Dichloromethane |
| Target Bacteria | Mycobacterium tuberculosis (ATCC 27294) |
| Assay / Test Done | BACTEC 460 (Becton Dickinson Diagnostic Instrument Systems, Sparks MD) Radiometric Assay |
| Positive Control Used (conc.) | Rifampin (2 µg/ml), Ethambutol (7.5 µg/ml) |
| Inhibition [%] | < 50 % |
| Activity [MIC] µg/ml | 50 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | 13678239 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Graham JG, Pendland SL, Prause JL, Danzinger LH, Schunke Vigo J, Cabieses F, Farnsworth NR.Antimycobacterial evaluation of Peruvian plants.Phytomedicine. 2003;10(6-7):528-35
|
| Curator | |
| Compound ID | 1710 |
| Compound Structure | |
| Plant Source | Eugenia uniflora L. Common Name:Pitaanga, Surinam Cherry (English) |
| Source Family | Myrtaceae |
| Origin | India |
| Plant Part Used | Leaf |
| Extract | Water |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | Agar - Well Diffusion Assay |
| Positive Control Used (conc.) | Gentamicin (20 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 0.01 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | < 0.5 mm |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Skin infections, microbial infections |
| PubMed ID [Source Literature] | 8844466 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Olano I, Paz EA, Cerdeíras MP, Fernández J, Ferreira F, Moyna P, Soubes M, Vazquez A, Vero S, Bassagoda MJ.Screening of Uruguayan medicinal plants for antimicrobial activity. Part II.J Ethnopharmacol. 1996 Aug;53(2):111-5
|
| Curator | |
| Compound ID | 2027 |
| Compound Structure | |
| Plant Source | Leptospermum scoparium Common Name:Manuka |
| Source Family | Myrtaceae |
| Origin | New Zealand |
| Plant Part Used | Leaf |
| Extract | |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | 96 well - plate format assay for bacteriostatic activity, two - fold serial dilution to measure any background optical density or fluorescence associated with the extract |
| Positive Control Used (conc.) | Rifampin (100 µM), Streptomycin (100 µM) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Colds, pains, urinary troubles |
| PubMed ID [Source Literature] | 20537175 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Earl EA, Altaf M, Murikoli RV, Swift S, O Toole R.Native New Zealand plants with inhibitory activity towards Mycobacterium tuberculosis.BMC Complement Altern Med. 2010 Jun 10;10:25
|
| Curator | |
| Compound ID | 2028 |
| Compound Structure | |
| Plant Source | Leptospermum scoparium Common Name:Manuka |
| Source Family | Myrtaceae |
| Origin | New Zealand |
| Plant Part Used | Flower |
| Extract | |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | 96 well - plate format assay for bacteriostatic activity, two - fold serial dilution to measure any background optical density or fluorescence associated with the extract |
| Positive Control Used (conc.) | Rifampin (100 µM), Streptomycin (100 µM) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Colds, pains, urinary troubles |
| PubMed ID [Source Literature] | 20537175 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Earl EA, Altaf M, Murikoli RV, Swift S, O Toole R.Native New Zealand plants with inhibitory activity towards Mycobacterium tuberculosis.BMC Complement Altern Med. 2010 Jun 10;10:25
|
| Curator | |
| Compound ID | 2152 |
| Compound Structure | |
| Plant Source | Melaleuca leucadendron L. syn. Melaleuca viridiflora Gaertn. Common Name:Cajeput Tree, Swamp Tea Tree, White Tea Tree (English) |
| Source Family | Myrtaceae |
| Origin | India |
| Plant Part Used | |
| Extract | Essential oil |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Expectorant, bronchitis |
| PubMed ID [Source Literature] | 17276637 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
|
| Curator | |
| Compound ID | 2177 |
| Compound Structure | |
| Plant Source | Metrosideros robusta Common Name:Northern Rata |
| Source Family | Myrtaceae |
| Origin | New Zealand |
| Plant Part Used | Leaf |
| Extract | |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | 96 well - plate format assay for bacteriostatic activity, two - fold serial dilution to measure any background optical density or fluorescence associated with the extract |
| Positive Control Used (conc.) | Rifampin (100 µM), Streptomycin (100 µM) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Sore throats |
| PubMed ID [Source Literature] | 20537175 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Earl EA, Altaf M, Murikoli RV, Swift S, O Toole R.Native New Zealand plants with inhibitory activity towards Mycobacterium tuberculosis.BMC Complement Altern Med. 2010 Jun 10;10:25
|
| Curator | |
| Compound ID | 2178 |
| Compound Structure | |
| Plant Source | Metrosideros umbellata Common Name:Southern Rata |
| Source Family | Myrtaceae |
| Origin | New Zealand |
| Plant Part Used | Leaf |
| Extract | |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | 96 well - plate format assay for bacteriostatic activity, two - fold serial dilution to measure any background optical density or fluorescence associated with the extract |
| Positive Control Used (conc.) | Rifampin (100 µM), Streptomycin (100 µM) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | 20537175 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Earl EA, Altaf M, Murikoli RV, Swift S, O Toole R.Native New Zealand plants with inhibitory activity towards Mycobacterium tuberculosis.BMC Complement Altern Med. 2010 Jun 10;10:25
|
| Curator | |
| Compound ID | 2222 |
| Compound Structure | |
| Plant Source | Myrcia dichasialis McVaugh Common Name: |
| Source Family | Myrtaceae |
| Origin | Peru |
| Plant Part Used | Bark |
| Extract | Dichloromethane |
| Target Bacteria | Mycobacterium tuberculosis (ATCC 27294) |
| Assay / Test Done | BACTEC 460 (Becton Dickinson Diagnostic Instrument Systems, Sparks MD) Radiometric Assay |
| Positive Control Used (conc.) | Rifampin (2 µg/ml), Ethambutol (7.5 µg/ml) |
| Inhibition [%] | 50 % |
| Activity [MIC] µg/ml | 50 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | 13678239 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Graham JG, Pendland SL, Prause JL, Danzinger LH, Schunke Vigo J, Cabieses F, Farnsworth NR.Antimycobacterial evaluation of Peruvian plants.Phytomedicine. 2003;10(6-7):528-35
|
| Curator | |
| Compound ID | 2230 |
| Compound Structure | |
| Plant Source | Myrtus communis L. Common Name:Myrtle (English) |
| Source Family | Myrtaceae |
| Origin | India |
| Plant Part Used | Leaf |
| Extract | Chloroform, methanol |
| Target Bacteria | Mycobacterium phlei |
| Assay / Test Done | Agar - Dilution Test |
| Positive Control Used (conc.) | Gentamicin (0.01 mg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 250 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Wound healing, antiseptic and disinfectant qualities, pulmonary disorders |
| PubMed ID [Source Literature] | 3325696 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Ríos JL, Recio MC, Villar A.Antimicrobial activity of selected plants employed in the Spanish Mediterranean area.J Ethnopharmacol. 1987 Nov;21(2):139-52
|
| Curator | |
| Compound ID | 2231 |
| Compound Structure | |
| Plant Source | Myrtus communis L. Common Name:Myrtle (English) |
| Source Family | Myrtaceae |
| Origin | India |
| Plant Part Used | Leaf |
| Extract | Ethanol (95 %) |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Wound healing, antiseptic and disinfectant qualities, cough, expectorant, chronic catarrh of lungs |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Frisbey, A., Roberts, J.M., Jennings, J.C., Gottshall, R.Y., Lucas, E.H., 1953. The occurrence of antibacterial substances in seed plants with special reference to Mycobacterium tuberculosis. Michigan State University Agricultural Applied Science Quaternary Bulletin 35, 392–404
|
| Curator | |
| Compound ID | 2452 |
| Compound Structure | |
| Plant Source | Psidium acutangulum DC. Common Name: |
| Source Family | Myrtaceae |
| Origin | Peru |
| Plant Part Used | Bark, stem |
| Extract | Dichloromethane |
| Target Bacteria | Mycobacterium tuberculosis (ATCC 27294) |
| Assay / Test Done | BACTEC 460 (Becton Dickinson Diagnostic Instrument Systems, Sparks MD) Radiometric Assay |
| Positive Control Used (conc.) | Rifampin (2 µg/ml), Ethambutol (7.5 µg/ml) |
| Inhibition [%] | < 50 % |
| Activity [MIC] µg/ml | 50 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | 13678239 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Graham JG, Pendland SL, Prause JL, Danzinger LH, Schunke Vigo J, Cabieses F, Farnsworth NR.Antimycobacterial evaluation of Peruvian plants.Phytomedicine. 2003;10(6-7):528-35
|
| Curator | |
