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| Compound ID | 2426 |
| Compound Structure | |
| Plant Source | Populus tremuloides Common Name:Aspen |
| Source Family | Salicaceae |
| Origin | British Columbia |
| Plant Part Used | |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis, Mycobacterium avium |
| Assay / Test Done | Disk Diffusion Assay |
| Positive Control Used (conc.) | Isoniazid |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 50 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Fever - reducer, pain - relief, anorexia, anti - inflammatory, arthritis and rheumatic pain, pulmonary infections |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) A.R. McCutcheon, R.W. Stokes, L.M. Thorson, S.M. Ellis, R.E.W. Hancock and G.H.N. Towers.Anti-Mycobacterial Screening of British Columbian Medicinal Plants.Pharmaceutical Biology, 1997, Vol. 35, No. 2 , Pages 77-83 2) http://medplant.nmsu.edu/aspen.shtml |
| Curator |
| Compound ID | 2427 |
| Compound Structure | |
| Plant Source | Populus tremuloides Common Name:Aspen |
| Source Family | Salicaceae |
| Origin | British Columbia |
| Plant Part Used | |
| Extract | Ethanol |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | 100 %, Partial |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | 1:320 dilution, 1:640 dilution |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Fever - reducer, pain - relief, anorexia, anti - inflammatory, arthritis and rheumatic pain, pulmonary infections |
| PubMed ID [Source Literature] | 2118130 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Grange JM, Davey RW. 1990. Detection of antituberculous activity in plant extracts. J Appl Bacteriol 68: 587±59 2) http://medplant.nmsu.edu/aspen.shtml |
| Curator |
| Compound ID | 2522 |
| Compound Structure | |
| Plant Source | Salix alba L. Common Name:White Willow, European Willow (English), Jalavetasa (Sanskrit) |
| Source Family | Salicaceae |
| Origin | India |
| Plant Part Used | Mother tinture |
| Extract | Ethanol |
| Target Bacteria | Mycobacterium tuberculosis H37Rv (human) |
| Assay / Test Done | Tube Dilution Test |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | 1:40 dilution |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Diarrhoea, dysentery, astringent, tonic, rheumatism |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Grange, J.M., Davey, R.W., 1990. Detection of antituberculous activity in plant extracts. Journal of Applied Bacteriology 68, 587–59 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India |
| Curator |
| Compound ID | 2523 |
| Compound Structure | |
| Plant Source | Salix caprea L. Common Name:Sallow, Goat Willow, Common Willow (English), Vetasa, Vaanira (Sanskrit) |
| Source Family | Salicaceae |
| Origin | India |
| Plant Part Used | Flower |
| Extract | Ethanol (95 %) |
| Target Bacteria | Mycobacterium tuberculosis and other bacterial species |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 1:80 dilution |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Expectorant |
| PubMed ID [Source Literature] | 10925394 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Newton SM, Lau C, Wright CW.A review of antimycobacterial natural products.Phytother Res. 2000 Aug;14(5):303-22 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India |
| Curator |
| Compound ID | 2524 |
| Compound Structure | |
| Plant Source | Salix mucronata Thunb. Common Name:Flute Willow, Safsaf Willow |
| Source Family | Salicaceae |
| Origin | Africa |
| Plant Part Used | Bark |
| Extract | Ethanol |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 1560 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Rheumatism, fever, rheumatic fever, wound dressing, pain relief and anti - infective |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251 2) Iwu, M.M., 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, Florida, USA 3) http://www.zimbabweflora.co.zw/speciesdata/species.php?species_id=120010 |
| Curator |
| Compound ID | 2525 |
| Compound Structure | |
| Plant Source | Salix mucronata Thunb. Common Name:Flute Willow, Safsaf Willow |
| Source Family | Salicaceae |
| Origin | Africa |
| Plant Part Used | Root |
| Extract | Dichloromethane |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 6250 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Rheumatism, fever, rheumatic fever, wound dressing, pain relief and anti - infective |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251 2) Iwu, M.M., 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, Florida, USA 3) http://www.zimbabweflora.co.zw/speciesdata/species.php?species_id=120010 |
| Curator |
| Compound ID | 2526 |
| Compound Structure | |
| Plant Source | Salix mucronata Thunb. Common Name:Flute Willow, Safsaf Willow |
| Source Family | Salicaceae |
| Origin | Africa |
| Plant Part Used | Root |
| Extract | Ethyl acetate |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 6250 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Rheumatism, fever, rheumatic fever, wound dressing, pain relief and anti - infective |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251 2) Iwu, M.M., 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, Florida, USA 3) http://www.zimbabweflora.co.zw/speciesdata/species.php?species_id=120010 |
| Curator |
| Compound ID | 2527 |
| Compound Structure | |
| Plant Source | Salix mucronata Thunb. Common Name:Flute Willow, Safsaf Willow |
| Source Family | Salicaceae |
| Origin | Africa |
| Plant Part Used | Root |
| Extract | Ethanol |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 1560 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Rheumatism, fever, rheumatic fever, wound dressing, pain relief and anti - infective |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251 2) Iwu, M.M., 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, Florida, USA 3) http://www.zimbabweflora.co.zw/speciesdata/species.php?species_id=120010 |
| Curator |
| Compound ID | 2528 |
| Compound Structure | |
| Plant Source | Salix mucronata Thunb. Common Name:Flute Willow, Safsaf Willow |
| Source Family | Salicaceae |
| Origin | Africa |
| Plant Part Used | Leaf |
| Extract | Dichloromethane |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 6250 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Rheumatism, fever, rheumatic fever, wound dressing, pain relief and anti - infective |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251 2) Iwu, M.M., 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, Florida, USA 3) http://www.zimbabweflora.co.zw/speciesdata/species.php?species_id=120010 |
| Curator |
| Compound ID | 2529 |
| Compound Structure | |
| Plant Source | Salix mucronata Thunb. Common Name:Flute Willow, Safsaf Willow |
| Source Family | Salicaceae |
| Origin | Africa |
| Plant Part Used | Leaf |
| Extract | Ethanol |
| Target Bacteria | Mycobacterium aurum A+ |
| Assay / Test Done | Broth Microdilution Method (BMM) |
| Positive Control Used (conc.) | Ciprofloxacin (1.8 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 1560 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Rheumatism, fever, rheumatic fever, wound dressing, pain relief and anti - infective |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) I.M.S. Eldeen, J. Van Staden.Antimycobacterial activity of some trees used in South African traditional medicine.South African Journal of Botany, Volume 73, Issue 2, April 2007, Pages 248–251 2) Iwu, M.M., 1993. Handbook of African Medicinal Plants. CRC Press, Boca Raton, Florida, USA 3) http://www.zimbabweflora.co.zw/speciesdata/species.php?species_id=120010 |
| Curator |
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