| Compound ID | 2599 |
| Compound Structure | |
| Plant Source | Smilax febrifuga Kunth Common Name: |
| Source Family | Smilacaceae |
| Origin | Peru |
| Plant Part Used | Leaf, root, stem |
| Extract | Dichloromethane |
| Target Bacteria | Mycobacterium tuberculosis (ATCC 27294) |
| Assay / Test Done | BACTEC 460 (Becton Dickinson Diagnostic Instrument Systems, Sparks MD) radiometric assay |
| Positive Control Used (conc.) | Rifampin (2 µg/ml), Ethambutol (7.5 µg/ml) |
| Inhibition [%] | < 50 % |
| Activity [MIC] µg/ml | 50 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | 13678239 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Graham JG, Pendland SL, Prause JL, Danzinger LH, Schunke Vigo J, Cabieses F, Farnsworth NR.Antimycobacterial evaluation of Peruvian plants.Phytomedicine. 2003;10(6-7):528-35
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| Curator | |
| Compound ID | 2600 |
| Compound Structure | |
| Plant Source | Smilax laurifolia Roxb. Common Name:Climbing Nightshade (English) |
| Source Family | Smilacaceae |
| Origin | India |
| Plant Part Used | Whole plant |
| Extract | Ethyl acetate, water |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | Agar - Well Diffusion Assay |
| Positive Control Used (conc.) | Streptomycin sulphate (1 mg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | 2 mm, 1 mm, 20 mm (control) |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | The allied species S. ovalifolia Roxb. for measles, gout, dysentery, small - pox, skin diseases, random screening |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) James D. Mcchesney, Robert P. Adams.Co-evaluation of plant extracts as petrochemical substitutes and for biologically active compounds.Economic Botany. 12/1984, 39(1):74-86
2) Sudhanshu Kumar Jain.Dictionary of Indian Folk Medicine and Ethnobotany:A Reference Manual of Man-Plant Relationships, Ethnic Groups & Ethnobotanists in India.Deep Publications, 1991 - 311 pages
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| Curator | |
