| Compound ID | 2692 |
| Compound Structure | |
| Plant Source | Taxus baccata L Common Name:European Yew (English), Thunera, Sthauneya, Sthauneyaka, Shukapushpa, Dhaatri - Patra, Vikarna (Sanskrit) |
| Source Family | Taxaceae |
| Origin | India |
| Plant Part Used | Leaf |
| Extract | Water |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | Broth Dilution Assay |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 1:80 dilution |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Expectorant |
| PubMed ID [Source Literature] | 17276637 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
2) Anonymous, 1986. The Useful Plants of India. Council of Scientific and Industrial Research, New Delhi, India
|
| Curator | |
| Compound ID | 2693 |
| Compound Structure | |
| Plant Source | Taxus baccata L Common Name:European Yew (English), Thunera, Sthauneya, Sthauneyaka, Shukapushpa, Dhaatri - Patra, Vikarna (Sanskrit) |
| Source Family | Taxaceae |
| Origin | India |
| Plant Part Used | Fruit |
| Extract | Water |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | Broth Dilution Assay |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | < 1:20 dilution |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Expectorant |
| PubMed ID [Source Literature] | 17276637 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
2) Anonymous, 1986. The Useful Plants of India. Council of Scientific and Industrial Research, New Delhi, India
|
| Curator | |
| Compound ID | 2694 |
| Compound Structure | |
| Plant Source | Taxus baccata L Common Name:European Yew (English), Thunera, Sthauneya, Sthauneyaka, Shukapushpa, Dhaatri - Patra, Vikarna (Sanskrit) |
| Source Family | Taxaceae |
| Origin | India |
| Plant Part Used | Wood |
| Extract | Chloroform |
| Target Bacteria | Mycobacterium tuberculosis H37Ra |
| Assay / Test Done | Microplate Alamar Blue Assay (MABA) |
| Positive Control Used (conc.) | Rifampin (0.0047 – 0.0095 µg/ml), Isoniazid (0.05 – 0.1 µg/ml), Kanamycin sulphate (2.5 – 5.0 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 200 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Expectorant |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) N. Erdemoglu, B. Sener and P. Palittapongarnpim.Antimycobacterial activity of Taxus baccata.Pharmaceutical Biology, 2003, Vol. 41, No. 8 , Pages 614-615
|
| Curator | |
| Compound ID | 2695 |
| Compound Structure | |
| Plant Source | Taxus baccata L Common Name:European Yew (English), Thunera, Sthauneya, Sthauneyaka, Shukapushpa, Dhaatri - Patra, Vikarna (Sanskrit) |
| Source Family | Taxaceae |
| Origin | India |
| Plant Part Used | Leaf |
| Extract | Ethanol (80 %) |
| Target Bacteria | Mycobacterium tuberculosis H37Ra |
| Assay / Test Done | Microplate Alamar Blue Assay (MABA) |
| Positive Control Used (conc.) | Rifampin (0.0047 – 0.0095 µg/ml), Isoniazid (0.05 – 0.1 µg/ml), Kanamycin sulphate (2.5 – 5.0 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 200 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Expectorant |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) N. Erdemoglu, B. Sener and P. Palittapongarnpim.Antimycobacterial activity of Taxus baccata.Pharmaceutical Biology, 2003, Vol. 41, No. 8 , Pages 614-615
|
| Curator | |
| Compound ID | 2696 |
| Compound Structure | |
| Plant Source | Taxus Canadensis Common Name:American Yew, Ground Hemlock, Yew |
| Source Family | Taxaceae |
| Origin | China |
| Plant Part Used | Leaf |
| Extract | Ethanol |
| Target Bacteria | Mycobacterium tuberculosis H37Rv |
| Assay / Test Done | |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | 1:80 dilution |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Used as an antitussive (preventing or relieving cough), menstrual stimulant, abortifacient, treat rheumatism, fever and arthritis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Lucas EH, Lickfeldt A, Gottshall RY, Jennings JC. 195 The occurrence of antibacterial substances in seed plants with special reference to Mycobacterium tuberculosis. Bull Torrey Bot Club 78: 310±32
2) http://www.healthline.com/natstandardcontent/yew
|
| Curator | |
