| Compound ID | 1059 |
| Compound Structure | N/A |
| Plant Source | Aegiphila chrysantha Hayek Common Name: |
| Source Family | Verbenaceae |
| Origin | Peru |
| Plant Part Used | Stem |
| Extract | Dichloromethane |
| Target Bacteria | Mycobacterium tuberculosis (ATCC 27294) |
| Assay / Test Done | BACTEC 460 (Becton Dickinson Diagnostic Instrument Systems, Sparks MD) Radiometric Assay |
| Positive Control Used (conc.) | Rifampin (2 µg/ml), Ethambutol (7.5 µg/ml) |
| Inhibition [%] | < 50 % |
| Activity [MIC] µg/ml | 50 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | N/A |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | 13678239 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Graham JG, Pendland SL, Prause JL, Danzinger LH, Schunke Vigo J, Cabieses F, Farnsworth NR.Antimycobacterial evaluation of Peruvian plants.Phytomedicine. 2003;10(6-7):528-35
|
| Curator | |
| Compound ID | 1228 |
| Compound Structure | |
| Plant Source | Avicennia germinans (L.)L. Common Name:Black Mangrove |
| Source Family | Verbenaceae |
| Origin | Puerto Rico |
| Plant Part Used | Leaf |
| Extract | Ethanol (95 %) |
| Target Bacteria | Mycobacterium tuberculosis H37Rv |
| Assay / Test Done | Middlebrook 7H9 Broth using BACTEC 460 System |
| Positive Control Used (conc.) | Rifampin |
| Inhibition [%] | 51 % |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | To treat tumours, diarrhoea, haemorrhage, haemorrhoids, rheumatism, swellings, wounds and sore throat |
| PubMed ID [Source Literature] | 11746852 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Antoun MD, Ramos Z, Vazques J, Oquendo I, Proctor GR, Gerena L, Franzblau SG.Evaluation of the flora of Puerto Rico for in vitro antiplasmodial and antimycobacterial activities.Phytother Res. 2001 Nov;15(7):638-42
2) http://www.prota4u.org/protav8.asp?h=M11,M12,M15,M18,M23,M25,M26,M27,M34,M36,M4,M6,M7,M9&t=Avicennia,germinans&p=Avicennia+germinans
|
| Curator | |
| Compound ID | 1459 |
| Compound Structure | |
| Plant Source | Citharexylum fruticosum L. Common Name:Florida Fiddlewood |
| Source Family | Verbenaceae |
| Origin | Puerto Rico |
| Plant Part Used | Stem |
| Extract | Ethanol (95 %) |
| Target Bacteria | Mycobacterium tuberculosis H37Rv |
| Assay / Test Done | Middlebrook 7H9 Broth using BACTEC 460 System |
| Positive Control Used (conc.) | Rifampin |
| Inhibition [%] | 43 % |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | 11746852 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Antoun MD, Ramos Z, Vazques J, Oquendo I, Proctor GR, Gerena L, Franzblau SG.Evaluation of the flora of Puerto Rico for in vitro antiplasmodial and antimycobacterial activities.Phytother Res. 2001 Nov;15(7):638-42
2) http://plants.usda.gov/java/profile?symbol=CISP3
|
| Curator | |
| Compound ID | 1487 |
| Compound Structure | |
| Plant Source | Clerodendrum indicum (L.) Kuntze Common Name:Tuber Flower, Turk's Turban, Skyrocket (English), Bhargi (Sanskrit) |
| Source Family | Verbenaceae |
| Origin | Malaysia |
| Plant Part Used | Flower, stem |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis H37Rv |
| Assay / Test Done | Colorimetric Tetrazolium Microplate Assay (TEMA) |
| Positive Control Used (conc.) | Isoniazid (0.078 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 1600 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Cough |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Chooi, O.H., 2006. Tanaman Hiasan, Khasiat Makanan dan Ubatan. Utusan Publications and Distributors Sdn Bhd, Kuala Lumpur, Malaysia
|
| Curator | |
| Compound ID | 1488 |
| Compound Structure | |
| Plant Source | Clerodendrum myricoides (Hochst)Vatke Common Name:Butterfly Bush, Blue Glory Bower |
| Source Family | Verbenaceae |
| Origin | Kenya |
| Plant Part Used | Root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 1, 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Gonorrhea, mumps, tuberculosis, chest problems, hepatitis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1489 |
| Compound Structure | |
| Plant Source | Clerodendrum myricoides (Hochst)Vatke Common Name:Butterfly Bush, Blue Glory Bower |
| Source Family | Verbenaceae |
| Origin | Kenya |
| Plant Part Used | Root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium kansasii |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Gonorrhea, mumps, tuberculosis, chest problems, hepatitis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1490 |
| Compound Structure | |
| Plant Source | Clerodendrum myricoides (Hochst)Vatke Common Name:Butterfly Bush, Blue Glory Bower |
| Source Family | Verbenaceae |
| Origin | Kenya |
| Plant Part Used | Root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium fortuitum |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 1, 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Gonorrhea, mumps, tuberculosis, chest problems, hepatitis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1491 |
| Compound Structure | |
| Plant Source | Clerodendrum myricoides (Hochst)Vatke Common Name:Butterfly Bush, Blue Glory Bower |
| Source Family | Verbenaceae |
| Origin | Kenya |
| Plant Part Used | Root |
| Extract | Methanol |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 1, 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Gonorrhea, mumps, tuberculosis, chest problems, hepatitis |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Richard M. Mariita, Paul O. Okemo , John A. Orodho, Claude Kirimuhuzya , Joseph N. Otieno ,Magadula J. Joseph EFFICACY OF 13 MEDICINAL PLANTS USED BY INDIGENOUS COMMUNITIES AROUND LAKE VICTORIA, KENYA, AGAINST TUBERCULOSIS, DIARRHOEA CAUSING BACTERIA AND CANDIDA ALBICANS International Journal Of Pharmacy&Technology ISSN: 0975-766X Available Online through Research Article www.ijptonline.com
|
| Curator | |
| Compound ID | 1986 |
| Compound Structure | |
| Plant Source | Lantana camara L. Common Name:Wild Sage, White Sage, Sage (English), Chaturangi, Vanacchedi (Sanskrit) |
| Source Family | Verbenaceae |
| Origin | Kenya, Malaysia |
| Plant Part Used | Leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Ulcers, tuberculosis, pneumonia, chest pains, malaria, asthma |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1987 |
| Compound Structure | |
| Plant Source | Lantana camara L. Common Name:Wild Sage, White Sage, Sage (English), Chaturangi, Vanacchedi (Sanskrit) |
| Source Family | Verbenaceae |
| Origin | Kenya, Malaysia |
| Plant Part Used | Leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium kansasii |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Ulcers, tuberculosis, pneumonia, chest pains, malaria, asthma |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1988 |
| Compound Structure | |
| Plant Source | Lantana camara L. Common Name:Wild Sage, White Sage, Sage (English), Chaturangi, Vanacchedi (Sanskrit) |
| Source Family | Verbenaceae |
| Origin | Kenya, Malaysia |
| Plant Part Used | Leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium fortuitum |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Ulcers, tuberculosis, pneumonia, chest pains, malaria, asthma |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1989 |
| Compound Structure | |
| Plant Source | Lantana camara L. Common Name:Wild Sage, White Sage, Sage (English), Chaturangi, Vanacchedi (Sanskrit) |
| Source Family | Verbenaceae |
| Origin | Kenya, Malaysia |
| Plant Part Used | Leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Ulcers, tuberculosis, pneumonia, chest pains, malaria, asthma |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1990 |
| Compound Structure | |
| Plant Source | Lantana camara L. Common Name:Wild Sage, White Sage, Sage (English), Chaturangi, Vanacchedi (Sanskrit) |
| Source Family | Verbenaceae |
| Origin | Kenya, Malaysia |
| Plant Part Used | Whole plant |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis H37Rv |
| Assay / Test Done | Colorimetric Tetrazolium Microplate Assay (TEMA) |
| Positive Control Used (conc.) | Isoniazid (0.078 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Ulcers, tuberculosis, pneumonia, chest pains, malaria, asthma |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Zakaria, M., Mohd, M.A., 1994. Traditional Malay Medicinal Plants. Fajar Bakti Sdn Bhd, Kuala Lumpur, Malaysia
|
| Curator | |
| Compound ID | 1991 |
| Compound Structure | |
| Plant Source | Lantana hispida Common Name:West Indian shrubverbena |
| Source Family | Verbenaceae |
| Origin | Mexico |
| Plant Part Used | Aerial |
| Extract | Hexane |
| Target Bacteria | Mycobacterium tuberculosis H37Rv |
| Assay / Test Done | Microplate Alamar Blue Assay (MABA) |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 25 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Cough, pneumonia, tuberculosis |
| PubMed ID [Source Literature] | 13680821 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Jimenez-Arellanes A, Meckes M, Ramirez R, Torres J, Luna-Herrera J.Activity against multidrug-resistant Mycobacterium tuberculosis in Mexican plants used to treat respiratory diseases.Phytother Res. 2003 Sep;17(8):903-8
|
| Curator | |
| Compound ID | 1992 |
| Compound Structure | |
| Plant Source | Lantana hispida Common Name:West Indian Shrubverbena |
| Source Family | Verbenaceae |
| Origin | Mexico |
| Plant Part Used | Aerial |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis H37Rv |
| Assay / Test Done | Microplate Alamar Blue Assay (MABA) |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 200 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Cough, pneumonia, tuberculosis |
| PubMed ID [Source Literature] | 13680821 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Jimenez-Arellanes A, Meckes M, Ramirez R, Torres J, Luna-Herrera J.Activity against multidrug-resistant Mycobacterium tuberculosis in Mexican plants used to treat respiratory diseases.Phytother Res. 2003 Sep;17(8):903-8
|
| Curator | |
| Compound ID | 1993 |
| Compound Structure | |
| Plant Source | Lantana trifolia L. Common Name:Shrub Verbena |
| Source Family | Verbenaceae |
| Origin | America, Kenya |
| Plant Part Used | Leaf |
| Extract | Hexane, dichloromethane |
| Target Bacteria | Mycobacterium tuberculosis H37Rv (ATCC 27 294) |
| Assay / Test Done | Microplate Alamar Blue Assay (MABA) |
| Positive Control Used (conc.) | Rifampin |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 100 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Heart problems, gonorrhea, tuberculosis, coughs |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) LEITAO, Suzana G. et al. Screening of Central and South American plant extracts for antimycobacterial activity by the Alamar Blue test. Rev. bras. farmacogn. [online]. 2006, vol.16, n.1, pp. 6-11
|
| Curator | |
| Compound ID | 1994 |
| Compound Structure | |
| Plant Source | Lantana trifolia L. Common Name:Shrub Verbena |
| Source Family | Verbenaceae |
| Origin | America, Kenya |
| Plant Part Used | Leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Heart problems, gonorrhea, tuberculosis, coughs |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1995 |
| Compound Structure | |
| Plant Source | Lantana trifolia L. Common Name:Shrub Verbena |
| Source Family | Verbenaceae |
| Origin | America, Kenya |
| Plant Part Used | Leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium kansasii |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Heart problems, gonorrhea, tuberculosis, coughs |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1996 |
| Compound Structure | |
| Plant Source | Lantana trifolia L. Common Name:Shrub Verbena |
| Source Family | Verbenaceae |
| Origin | America, Kenya |
| Plant Part Used | Leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium fortuitum |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2, 1 and 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Heart problems, gonorrhea, tuberculosis, coughs |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 1997 |
| Compound Structure | |
| Plant Source | Lantana trifolia L. Common Name:Shrub Verbena |
| Source Family | Verbenaceae |
| Origin | America, Kenya |
| Plant Part Used | Leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | BACTEC MGIT™ 960 System |
| Positive Control Used (conc.) | Isoniazid (2,1 & 0.5 mg/ml) |
| Inhibition [%] | 100 % |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Heart problems, gonorrhea, tuberculosis, coughs |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
|
| Curator | |
| Compound ID | 2046 |
| Compound Structure | |
| Plant Source | Lippea nodiflora Rich.syn. Phyla nodiflora (L.) Greene Common Name:Wild Sage (English), Jalapippali, Shaaradi (Sanskrit) |
| Source Family | Verbenaceae |
| Origin | India |
| Plant Part Used | Aerial |
| Extract | Methanol |
| Target Bacteria | Mycobacterium phlei |
| Assay / Test Done | Disk Diffusion Assay |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 300000 µg/ml of dried plant material |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Asthma, bronchitis, diuretic, febrifuge, boils, swollen cervical glands, chronic indolent ulcers |
| PubMed ID [Source Literature] | 8866730 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Taylor RS, Edel F, Manandhar NP, Towers GH.Antimicrobial activities of southern Nepalese medicinal plants.J Ethnopharmacol. 1996 Feb;50(2):97-102
2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India
|
| Curator | |
| Compound ID | 2047 |
| Compound Structure | |
| Plant Source | Lippia alba (Miller) N. E.Brown Common Name: |
| Source Family | Verbenaceae |
| Origin | Peru |
| Plant Part Used | Whole plant |
| Extract | Dichloromethane |
| Target Bacteria | Mycobacterium tuberculosis (ATCC 27294) |
| Assay / Test Done | BACTEC 460 (Becton Dickinson Diagnostic Instrument Systems, Sparks MD) Radiometric Assay |
| Positive Control Used (conc.) | Rifampin (2 µg/ml), Ethambutol (7.5 µg/ml) |
| Inhibition [%] | < 50 % |
| Activity [MIC] µg/ml | 50 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis |
| PubMed ID [Source Literature] | 13678239 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Graham JG, Pendland SL, Prause JL, Danzinger LH, Schunke Vigo J, Cabieses F, Farnsworth NR.Antimycobacterial evaluation of Peruvian plants.Phytomedicine. 2003;10(6-7):528-35
|
| Curator | |
| Compound ID | 2048 |
| Compound Structure |  |
| Plant Source | Lippia alba (Miller) N. E.Brown Common Name: |
| Source Family | Verbenaceae |
| Origin | Colombia, Puerto Rico, India |
| Plant Part Used | Leaf, stem |
| Extract | Essential oil (2.5 %) |
| Target Bacteria | Mycobacterium tuberculosis H37Rv |
| Assay / Test Done | Macrodilution method in glass tubes |
| Positive Control Used (conc.) | Rifampin (0.50 µg/ml), Isoniazid (0.03 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 130 ± 95 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | Geranial |
| PubChem ID | 638011 |
| Ethnomedicinal Information | Digestive troubles in general, nausea, bronchitis, sore throat, flu, cough, cold, hypertension, skin diseases, wounds, stomach ache, nervous complaints, folklore medicine of Puerto Rico |
| PubMed ID [Source Literature] | 19753839 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | Aliphatic, Alkene, Terpene, Monoterpene, Aldehyde |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Molecular Weight | 152.120 |
| Molecular Formula | C10H16O
|
| SMILES | O=C/C=C(/CCC=C(C)C)C |
| XLogP | 2.701 |
| PSA | 17.070 |
| H-bond Donor | 0 |
| H-bond Acceptor | 1 |
| No. of Rotatable Bond Count | 4 |
| No. of Rings | 0 |
| No. of N | 0 |
| No. of O | 1 |
| No. of S | 0 |
| Reference(s) | 1) Bueno-Sánchez JG, Martínez-Morales JR, Stashenko EE, Ribón W.Anti-tubercular activity of eleven aromatic and medicinal plants occurring in Colombia.Biomedica. 2009 Mar;29(1):51-60
2) Thierry Hennebelle, Sevser Sahpaz, Henry Joseph, François Bailleul.Ethnopharmacology of Lippia alba.Journal of Ethnopharmacology, Volume 116, Issue 2, 5 March 2008, Pages 211-222
|
| Curator | |
| Compound ID | 2049 |
| Compound Structure |  |
| Plant Source | Lippia alba (Miller) N. E.Brown Common Name: |
| Source Family | Verbenaceae |
| Origin | Colombia, Puerto Rico, India |
| Plant Part Used | Leaf, stem |
| Extract | Essential oil (2.5 %) |
| Target Bacteria | Mycobacterium tuberculosis H37Rv |
| Assay / Test Done | Macrodilution method in glass tubes |
| Positive Control Used (conc.) | Rifampin (0.50 µg/ml), Isoniazid (0.03 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 130 ± 95 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | Neral |
| PubChem ID | 643779 |
| Ethnomedicinal Information | Digestive troubles in general, nausea, bronchitis, sore throat, flu, cough, cold, hypertension, skin diseases, wounds, stomach ache, nervous complaints, folklore medicine of Puerto Rico |
| PubMed ID [Source Literature] | 19753839 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | Aliphatic, Alkene, Aldehyde |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Molecular Weight | 152.120 |
| Molecular Formula | C10H16O
|
| SMILES | O=C/C=C(CCC=C(C)C)/C |
| XLogP | 2.701 |
| PSA | 17.070 |
| H-bond Donor | 0 |
| H-bond Acceptor | 1 |
| No. of Rotatable Bond Count | 4 |
| No. of Rings | 0 |
| No. of N | 0 |
| No. of O | 1 |
| No. of S | 0 |
| Reference(s) | 1) Bueno-Sánchez JG, Martínez-Morales JR, Stashenko EE, Ribón W.Anti-tubercular activity of eleven aromatic and medicinal plants occurring in Colombia.Biomedica. 2009 Mar;29(1):51-60
2) Thierry Hennebelle, Sevser Sahpaz, Henry Joseph, François Bailleul.Ethnopharmacology of Lippia alba.Journal of Ethnopharmacology, Volume 116, Issue 2, 5 March 2008, Pages 211-222
|
| Curator | |
| Compound ID | 2050 |
| Compound Structure |  |
| Plant Source | Lippia alba (Miller) N. E.Brown Common Name: |
| Source Family | Verbenaceae |
| Origin | Colombia, Puerto Rico, India |
| Plant Part Used | Leaf, stem |
| Extract | Essential oil (2.5 %) |
| Target Bacteria | Mycobacterium tuberculosis H37Rv |
| Assay / Test Done | Macrodilution method in glass tubes |
| Positive Control Used (conc.) | Rifampin (0.50 µg/ml), Isoniazid (0.03 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 64 - 128 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | Geraniol |
| PubChem ID | 637566 |
| Ethnomedicinal Information | Digestive troubles in general, nausea, bronchitis, sore throat, flu, cough, cold, hypertension, skin diseases, wounds, stomach ache, nervous complaints, folklore medicine of Puerto Rico |
| PubMed ID [Source Literature] | 19753839 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | Aliphatic, Alkene, Terpene, Monoterpene |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Molecular Weight | 154.136 |
| Molecular Formula | C10H18O
|
| SMILES | OC/C=C(/CCC=C(C)C)C |
| XLogP | 2.524 |
| PSA | 20.230 |
| H-bond Donor | 1 |
| H-bond Acceptor | 1 |
| No. of Rotatable Bond Count | 4 |
| No. of Rings | 0 |
| No. of N | 0 |
| No. of O | 1 |
| No. of S | 0 |
| Reference(s) | 1) Bueno-Sánchez JG, Martínez-Morales JR, Stashenko EE, Ribón W.Anti-tubercular activity of eleven aromatic and medicinal plants occurring in Colombia.Biomedica. 2009 Mar;29(1):51-60
2) Thierry Hennebelle, Sevser Sahpaz, Henry Joseph, François Bailleul.Ethnopharmacology of Lippia alba.Journal of Ethnopharmacology, Volume 116, Issue 2, 5 March 2008, Pages 211-222
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| Curator | |
