| Compound ID | 1147 |
| Compound Structure | |
| Plant Source | Aloe vera L. Common Name:Aloe vera (English) |
| Source Family | Xanthorrhoeaceae |
| Origin | India, Malaysia |
| Plant Part Used | Leaf |
| Extract | Pure gel |
| Target Bacteria | Mycobacterium tuberculosis H37Rv |
| Assay / Test Done | Middlebrook 7H9 Broth using BacT/ALERT 3D System |
| Positive Control Used (conc.) | Isoniazid, Rifampin |
| Inhibition [%] | 41 % |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Asthma and cough |
| PubMed ID [Source Literature] | 20571171 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
|
| Curator | |
| Compound ID | 1148 |
| Compound Structure | |
| Plant Source | Aloe vera L. Common Name:Aloe vera (English) |
| Source Family | Xanthorrhoeaceae |
| Origin | India, Malaysia |
| Plant Part Used | Leaf |
| Extract | Pure gel |
| Target Bacteria | Mycobacterium tuberculosis (Multi - Drug Resistant isolate DKU 156) |
| Assay / Test Done | Middlebrook 7H9 Broth using BacT/ALERT 3D System |
| Positive Control Used (conc.) | Isoniazid, Rifampin |
| Inhibition [%] | 32 % |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Asthma and cough |
| PubMed ID [Source Literature] | 20571171 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
|
| Curator | |
| Compound ID | 1149 |
| Compound Structure | |
| Plant Source | Aloe vera L. Common Name:Aloe vera (English) |
| Source Family | Xanthorrhoeaceae |
| Origin | India, Malaysia |
| Plant Part Used | Leaf |
| Extract | Pure gel |
| Target Bacteria | MDR stain of Mycobacterium tuberculosis (JAL1236) |
| Assay / Test Done | Middlebrook 7H9 Broth using BacT/ALERT 3D System |
| Positive Control Used (conc.) | Isoniazid, Rifampin |
| Inhibition [%] | 85 % |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Asthma and cough |
| PubMed ID [Source Literature] | 20571171 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
|
| Curator | |
| Compound ID | 1150 |
| Compound Structure | |
| Plant Source | Aloe vera L. Common Name:Aloe vera (English) |
| Source Family | Xanthorrhoeaceae |
| Origin | India, Malaysia |
| Plant Part Used | Leaf |
| Extract | Pure gel |
| Target Bacteria | Mycobacterium fortuitum (TMC 1529) |
| Assay / Test Done | Middlebrook 7H9 Broth using BacT/ALERT 3D System |
| Positive Control Used (conc.) | Isoniazid, Rifampin |
| Inhibition [%] | 0 % |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Asthma and cough |
| PubMed ID [Source Literature] | 20571171 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
|
| Curator | |
| Compound ID | 1151 |
| Compound Structure | |
| Plant Source | Aloe vera L. Common Name:Aloe vera (English) |
| Source Family | Xanthorrhoeaceae |
| Origin | India, Malaysia |
| Plant Part Used | Leaf |
| Extract | Methanol |
| Target Bacteria | Mycobacterium tuberculosis H37Rv |
| Assay / Test Done | Colorimetric Tetrazolium Microplate Assay (TEMA) |
| Positive Control Used (conc.) | Isoniazid (0.078 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 1600 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Asthma and cough |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Chooi, O.H., 2006. Tanaman Hiasan, Khasiat Makanan dan Ubatan. Utusan Publications and Distributors Sdn Bhd, Kuala Lumpur, Malaysia
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| Curator | |
