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                  Page - 1 of 1                  Record - 1 of 3   [TOP]
Compound ID3758
Compound Structure
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Plant SourceArtcarpus rigidus BLUME subsp. rigidus     Common Name:NR
Source FamilyMoraceae
OriginNR
Plant Part UsedNR
ExtractNR
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)NR
Inhibition [%]NR
Activity [MIC] µg/ml12.5 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedArtoindonesianin C
PubChem ID   10552003
Ethnomedicinal InformationNR
PubMed ID [Source Literature]17015984
Extract PreparationThe dried root bark (1.5 kg) was milled and extracted successively with n - hexane, CHCl3 and MeOH in a Soxhlet extraction apparatus. The extracts were evaporated to dryness under reduced pressure at about 40°C. The hexane extract (brownish syrup, 8.4 g), the CHCl3 extract (dark brownish sticky solid, 16.1 g) and the methanolic extract (dark brownish mass, 45.6 g) were obtained, respectively
Chemical Classification [Active Compound]Aromatic, Pentacyclic, Xanthonoid, Benzopyran, Phenol, Alcohol
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]Against human epidermoid carcinoma in the mouth (KB), human breast cancer cells (BC), human lung cancer cells (NCI - H187)
Molecular Weight462.131
Molecular FormulaC26H22O8
SMILESO1c2c3c(C(O)(CC3=O)C(=O)OC)c(cc2c(=O)c2c1c1c(OC(C=C1)(C)C)cc2O)C(=C)C
XLogP1.501
PSA110.130
H-bond Donor2
H-bond Acceptor7
No. of Rotatable Bond Count3
No. of Rings5
No. of N0
No. of O8
No. of S0
Reference(s)1) Namdaung U, Aroonrerk N, Suksamrarn S, Danwisetkanjana K, Saenboonrueng J, Arjchomphu W, Suksamrarn A.Bioactive constituents of the root bark of Artocarpus rigidus subsp. rigidus.Chem Pharm Bull (Tokyo). 2006 Oct;54(10):1433-6

CuratorReshmi, vikramjitmandal, rachanake

                  Record - 2 of 3   [TOP]
Compound ID3759
Compound Structure
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Plant SourceArtcarpus rigidus BLUME subsp. rigidus     Common Name:NR
Source FamilyMoraceae
OriginNR
Plant Part UsedNR
ExtractNR
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)NR
Inhibition [%]NR
Activity [MIC] µg/ml6.25 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedArtonin F
PubChem ID   14680593
Ethnomedicinal InformationNR
PubMed ID [Source Literature]17015984
Extract PreparationThe dried root bark (1.5 kg) was milled and extracted successively with n - hexane, CHCl3 and MeOH in a Soxhlet extraction apparatus. The extracts were evaporated to dryness under reduced pressure at about 40°C. The hexane extract (brownish syrup, 8.4 g), the CHCl3 extract (dark brownish sticky solid, 16.1 g) and the methanolic extract (dark brownish mass, 45.6 g) were obtained, respectively
Chemical Classification [Active Compound]Aromatic, Pentacyclic, Flavonoid, Benzopyran, Benzofuranoid, Phenol
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]Against human epidermoid carcinoma in the mouth (KB), human breast cancer cells (BC), human lung cancer cells (NCI - H187)
Molecular Weight502.199
Molecular FormulaC30H30O7
SMILESO1C(C2c3c1c(O)cc(O)c3c1oc3c(c(=O)c1C2)c(O)c(c1OC(C=Cc31)(C)C)CC=C(C)C)(C)C
XLogP3.394
PSA96.220
H-bond Donor3
H-bond Acceptor6
No. of Rotatable Bond Count2
No. of Rings6
No. of N0
No. of O7
No. of S0
Reference(s)1) Namdaung U, Aroonrerk N, Suksamrarn S, Danwisetkanjana K, Saenboonrueng J, Arjchomphu W, Suksamrarn A.Bioactive constituents of the root bark of Artocarpus rigidus subsp. rigidus.Chem Pharm Bull (Tokyo). 2006 Oct;54(10):1433-6

CuratorReshmi, vikramjitmandal, rachanake

                  Record - 3 of 3   [TOP]
Compound ID3760
Compound Structure
DOWNLOAD:
Plant SourceArtcarpus rigidus BLUME subsp. rigidus     Common Name:NR
Source FamilyMoraceae
OriginNR
Plant Part UsedNR
ExtractNR
Target BacteriaMycobacterium tuberculosis H37Ra
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)NR
Inhibition [%]NR
Activity [MIC] µg/ml12.5 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedArtorigidusin
PubChem IDNR
Ethnomedicinal InformationNR
PubMed ID [Source Literature]17015984
Extract PreparationThe dried root bark (1.5 kg) was milled and extracted successively with n - hexane, CHCl3 and MeOH in a Soxhlet extraction apparatus. The extracts were evaporated to dryness under reduced pressure at about 40°C. The hexane extract (brownish syrup, 8.4 g), the CHCl3 extract (dark brownish sticky solid, 16.1 g) and the methanolic extract (dark brownish mass, 45.6 g) were obtained, respectively
Chemical Classification [Active Compound]Aromatic, Tricyclic, Flavonoid, Benzopyran, Phenol
Media / Broth Used [Antimicrobial Assay/Test]NR
Cytotoxicity Assay [AID]Against human epidermoid carcinoma in the mouth (KB), human breast cancer cells (BC), human lung cancer cells (NCI - H187)
Molecular Weight384.194
Molecular FormulaC23H28O5
SMILESC1=Cc2c(OC1(C)C)cc(c1c2oc(c(c1=O)CCC(C)(C)C)CC(=O)C)O
XLogP4.155
PSA63.600
H-bond Donor1
H-bond Acceptor4
No. of Rotatable Bond Count5
No. of Rings3
No. of N0
No. of O5
No. of S0
Reference(s)1) Namdaung U, Aroonrerk N, Suksamrarn S, Danwisetkanjana K, Saenboonrueng J, Arjchomphu W, Suksamrarn A.Bioactive constituents of the root bark of Artocarpus rigidus subsp. rigidus.Chem Pharm Bull (Tokyo). 2006 Oct;54(10):1433-6

CuratorReshmi, vikramjitmandal, rachanake


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