BioPhytMol: A database of Phytomolecules against Mycobacteria

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Page - 1 of 1 Record - 1 of 18 [TOP]

Compound ID	1944
Compound Structure
Plant Source	Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)
Source Family	Cupressaceae
Origin	Worldwide, Mexico, India, British Columbia, particularly in Europe
Plant Part Used	Berry
Extract	Methanol (21.82 %)
Target Bacteria	Mycobacterium aurum
Assay / Test Done	Broth Microdilution Method (BMM)
Positive Control Used (conc.)	Streptomycin (IC50 value 1.14)
Inhibition [%]
Activity [MIC] µg/ml	> 500 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Antiseptic properties. In France berries used in treatment of scrofula and chest complaints
PubMed ID [Source Literature]	11744296
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67 2) http://plants.usda.gov/java/profile?symbol=JUCO6
Curator

Record - 2 of 18 [TOP]

Compound ID	1945
Compound Structure
Plant Source	Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)
Source Family	Cupressaceae
Origin	Worldwide, Mexico, India, British Columbia, particularly in Europe
Plant Part Used	Berry
Extract	Methanol (21.82 %)
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Broth Microdilution Method (BMM)
Positive Control Used (conc.)	Streptomycin (IC50 value 0.17)
Inhibition [%]
Activity [MIC] µg/ml	> 500 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Antiseptic properties. In France berries used in treatment of scrofula and chest complaints
PubMed ID [Source Literature]	11744296
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Newton SM, Lau C, Gurcha SS, Besra GS, Wright CW.The evaluation of forty-three plant species for in vitro antimycobacterial activities; isolation of active constituents from Psoralea corylifolia and Sanguinaria canadensis.J Ethnopharmacol. 2002 Jan;79(1):57-67 2) http://plants.usda.gov/java/profile?symbol=JUCO6
Curator

Record - 3 of 18 [TOP]

Compound ID	1946
Compound Structure
Plant Source	Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)
Source Family	Cupressaceae
Origin	Worldwide, Mexico, India, British Columbia, particularly in Europe
Plant Part Used	Leaf
Extract	Hexane, methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv (Isoniazid and Ethambutol resistant)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	100 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Antiseptic properties. In France berries used in treatment of scrofula and chest complaints
PubMed ID [Source Literature]	13680821
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Jimenez-Arellanes A, Meckes M, Ramirez R, Torres J, Luna-Herrera J.Activity against multidrug-resistant Mycobacterium tuberculosis in Mexican plants used to treat respiratory diseases.Phytother Res. 2003 Sep;17(8):903-8 2) http://plants.usda.gov/java/profile?symbol=JUCO6
Curator

Record - 4 of 18 [TOP]

Compound ID	1947
Compound Structure
Plant Source	Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)
Source Family	Cupressaceae
Origin	Worldwide, Mexico, India, British Columbia, particularly in Europe
Plant Part Used	Leaf
Extract	Hexane, methanol
Target Bacteria	Mycobacterium tuberculosis H37Rv (Rifampin resistant)
Assay / Test Done	Microplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	200 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Antiseptic properties. In France berries used in treatment of scrofula and chest complaints
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Jimenez-Arellanes A, Meckes M, Ramirez R, Torres J, Luna-Herrera J.Activity against multidrug-resistant Mycobacterium tuberculosis in Mexican plants used to treat respiratory diseases.Phytother Res. 2003 Sep;17(8):903-8 2) http://plants.usda.gov/java/profile?symbol=JUCO6
Curator

Record - 5 of 18 [TOP]

Compound ID	1948
Compound Structure
Plant Source	Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)
Source Family	Cupressaceae
Origin	Worldwide, Mexico, India, British Columbia, particularly in Europe
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium tuberculosis
Assay / Test Done	Broth Dilution Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	1:40 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Antiseptic properties. In France berries used in treatment of scrofula and chest complaints
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) http://plants.usda.gov/java/profile?symbol=JUCO6
Curator

Record - 6 of 18 [TOP]

Compound ID	1949
Compound Structure
Plant Source	Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)
Source Family	Cupressaceae
Origin	Worldwide, Mexico, India, British Columbia, particularly in Europe
Plant Part Used	Mother tinture
Extract	Ethanol (95 %)
Target Bacteria	Mycobacterium tuberculosis H37Rv (human)
Assay / Test Done	Tube Dilution Test
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	1:40 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Antiseptic properties. In France berries used in treatment of scrofula and chest complaints
PubMed ID [Source Literature]	2118130
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Grange JM, Davey RW.Detection of antituberculous activity in plant extracts.J Appl Bacteriol. 1990 Jun;68(6):587-91 2) http://plants.usda.gov/java/profile?symbol=JUCO6
Curator

Record - 7 of 18 [TOP]

Compound ID	1950
Compound Structure
Plant Source	Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)
Source Family	Cupressaceae
Origin	Worldwide, Mexico, India, British Columbia, particularly in Europe
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis, Mycobacterium avium
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Isoniazid (10 µl of mg/ml)
Inhibition [%]	100 %
Activity [MIC] µg/ml	50 µg extract/Disc
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Antiseptic properties. In France berries used in treatment of scrofula and chest complaints
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) A.R. McCutcheon, R.W. Stokes, L.M. Thorson, S.M. Ellis, R.E.W. Hancock and G.H.N. Towers.Anti-Mycobacterial Screening of British Columbian Medicinal Plants.Pharmaceutical Biology, 1997, Vol. 35, No. 2 , Pages 77-83 2) http://plants.usda.gov/java/profile?symbol=JUCO6
Curator

Record - 8 of 18 [TOP]

Compound ID

1951

Compound Structure

Plant Source

Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)

Source Family

Cupressaceae

Origin

Worldwide, Mexico, India, British Columbia, particularly in Europe

Plant Part Used

Root

Extract

Target Bacteria

Mycobacterium tuberculosis H37Rv

Assay / Test Done

Low Oxygen Recovery Assay (LORA)

Positive Control Used (conc.)

Inhibition [%]

97.7 %

Activity [MIC] µg/ml

100 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Longifolene

PubChem ID

289151

Ethnomedicinal Information

Antiseptic properties. In France berries used in treatment of scrofula and chest complaints

PubMed ID [Source Literature]

19755141

Extract Preparation

N/A

Chemical Classification [Active Compound]

Alicyclic, Terpene, Sesquiterpene

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

Against mammalian Vero cells (ATCC CCL-81)

Molecular Weight

204.188

Molecular Formula

C₁₅H₂₄

SMILES

C12C3C(C(=C)C1CC3)(CCCC2(C)C)C

XLogP

6.444

PSA

0.000

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Gordien AY, Gray AI, Franzblau SG, Seidel V.Antimycobacterial terpenoids from Juniperus communis L. (Cuppressaceae).J Ethnopharmacol. 2009 Dec 10;126(3):500-5

2) http://plants.usda.gov/java/profile?symbol=JUCO6

Curator

Record - 9 of 18 [TOP]

Compound ID

1952

Compound Structure

Plant Source

Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)

Source Family

Cupressaceae

Origin

Worldwide, Mexico, India, British Columbia, particularly in Europe

Plant Part Used

Root

Extract

Target Bacteria

Mycobacterium tuberculosis H37Rv

Assay / Test Done

Microplate Alamar Blue Assay (MABA)

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

21.1 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Totarol

PubChem ID

92783

Ethnomedicinal Information

Antiseptic properties. In France berries used in treatment of scrofula and chest complaints

PubMed ID [Source Literature]

19755141

Extract Preparation

N/A

Chemical Classification [Active Compound]

Alicyclic, Tricyclic, Terpene, Meroterpene, Phenol

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

286.230

Molecular Formula

C₂₀H₃₀O

SMILES

Oc1c(c2c([C@@]3([C@H](C(CCC3)(C)C)CC2)C)cc1)C(C)C

XLogP

8.211

PSA

20.230

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

Curator

Record - 10 of 18 [TOP]

Compound ID

1953

Compound Structure

Plant Source

Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)

Source Family

Cupressaceae

Origin

Worldwide, Mexico, India, British Columbia, particularly in Europe

Plant Part Used

Root

Extract

Target Bacteria

Non-replicating Mycobacterium tuberculosis H37Rv

Assay / Test Done

Low Oxygen Recovery Assay (LORA)

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

23.3 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Totarol

PubChem ID

92783

Ethnomedicinal Information

Antiseptic properties. In France berries used in treatment of scrofula and chest complaints

PubMed ID [Source Literature]

19755141

Extract Preparation

N/A

Chemical Classification [Active Compound]

Alicyclic, Tricyclic, Terpene, Meroterpene, Phenol

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

286.230

Molecular Formula

C₂₀H₃₀O

SMILES

Oc1c(c2c([C@@]3([C@H](C(CCC3)(C)C)CC2)C)cc1)C(C)C

XLogP

8.211

PSA

20.230

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

Curator

Record - 11 of 18 [TOP]

Compound ID

1954

Compound Structure

Plant Source

Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)

Source Family

Cupressaceae

Origin

Worldwide, Mexico, India, British Columbia, particularly in Europe

Plant Part Used

Root

Extract

Target Bacteria

Mycobacterium tuberculosis (Isoniazid - resistant variant)

Assay / Test Done

Microplate Alamar Blue Assay (MABA)

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

11 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Totarol

PubChem ID

92783

Ethnomedicinal Information

Antiseptic properties. In France berries used in treatment of scrofula and chest complaints

PubMed ID [Source Literature]

19755141

Extract Preparation

N/A

Chemical Classification [Active Compound]

Alicyclic, Tricyclic, Terpene, Meroterpene, Phenol

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

286.230

Molecular Formula

C₂₀H₃₀O

SMILES

Oc1c(c2c([C@@]3([C@H](C(CCC3)(C)C)CC2)C)cc1)C(C)C

XLogP

8.211

PSA

20.230

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

Curator

Record - 12 of 18 [TOP]

Compound ID

1955

Compound Structure

Plant Source

Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)

Source Family

Cupressaceae

Origin

Worldwide, Mexico, India, British Columbia, particularly in Europe

Plant Part Used

Root

Extract

Target Bacteria

Mycobacterium tuberculosis (Streptomycin - resistant variant)

Assay / Test Done

Microplate Alamar Blue Assay (MABA)

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

23.9 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Totarol

PubChem ID

92783

Ethnomedicinal Information

Antiseptic properties. In France berries used in treatment of scrofula and chest complaints

PubMed ID [Source Literature]

19755141

Extract Preparation

N/A

Chemical Classification [Active Compound]

Alicyclic, Tricyclic, Terpene, Meroterpene, Phenol

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

286.230

Molecular Formula

C₂₀H₃₀O

SMILES

Oc1c(c2c([C@@]3([C@H](C(CCC3)(C)C)CC2)C)cc1)C(C)C

XLogP

8.211

PSA

20.230

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

Curator

Record - 13 of 18 [TOP]

Compound ID

1956

Compound Structure

Plant Source

Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)

Source Family

Cupressaceae

Origin

Worldwide, Mexico, India, British Columbia, particularly in Europe

Plant Part Used

Root

Extract

Target Bacteria

Mycobacterium tuberculosis (Moxifloxacin - resistant variant)

Assay / Test Done

Microplate Alamar Blue Assay (MABA)

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

17.2 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Totarol

PubChem ID

92783

Ethnomedicinal Information

Antiseptic properties. In France berries used in treatment of scrofula and chest complaints

PubMed ID [Source Literature]

19755141

Extract Preparation

N/A

Chemical Classification [Active Compound]

Alicyclic, Tricyclic, Terpene, Meroterpene, Phenol

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

286.230

Molecular Formula

C₂₀H₃₀O

SMILES

Oc1c(c2c([C@@]3([C@H](C(CCC3)(C)C)CC2)C)cc1)C(C)C

XLogP

8.211

PSA

20.230

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

Curator

Record - 14 of 18 [TOP]

Compound ID

1957

Compound Structure

Plant Source

Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)

Source Family

Cupressaceae

Origin

Worldwide, Mexico, India, British Columbia, particularly in Europe

Plant Part Used

Root

Extract

Target Bacteria

Mycobacterium tuberculosis (Rifampin resistant variant)

Assay / Test Done

Microplate Alamar Blue Assay (MABA)

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

5.8 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Totarol

PubChem ID

92783

Ethnomedicinal Information

Antiseptic properties. In France berries used in treatment of scrofula and chest complaints

PubMed ID [Source Literature]

19755141

Extract Preparation

N/A

Chemical Classification [Active Compound]

Alicyclic, Tricyclic, Terpene, Meroterpene, Phenol

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

286.230

Molecular Formula

C₂₀H₃₀O

SMILES

Oc1c(c2c([C@@]3([C@H](C(CCC3)(C)C)CC2)C)cc1)C(C)C

XLogP

8.211

PSA

20.230

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

Curator

Record - 15 of 18 [TOP]

Compound ID

1958

Compound Structure

Plant Source

Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)

Source Family

Cupressaceae

Origin

Worldwide, Mexico, India, British Columbia, particularly in Europe

Plant Part Used

Root

Extract

Target Bacteria

Mycobacterium aurum, Mycobacterium phlei, Mycobacterium fortuitum, Mycobacterium smegmatis

Assay / Test Done

Broth Microdilution Method (BMM)

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

2 - 4 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Totarol

PubChem ID

92783

Ethnomedicinal Information

Antiseptic properties. In France berries used in treatment of scrofula and chest complaints

PubMed ID [Source Literature]

19755141

Extract Preparation

N/A

Chemical Classification [Active Compound]

Alicyclic, Tricyclic, Terpene, Meroterpene, Phenol

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

286.230

Molecular Formula

C₂₀H₃₀O

SMILES

Oc1c(c2c([C@@]3([C@H](C(CCC3)(C)C)CC2)C)cc1)C(C)C

XLogP

8.211

PSA

20.230

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

Curator

Record - 16 of 18 [TOP]

Compound ID

1959

Compound Structure

Plant Source

Juniperus communis Linn. Common Name:Common Juniper (English), Hapushaa, Havushaa, Haauber, Matsyagandha (Sanskrit)

Source Family

Cupressaceae

Origin

Worldwide, Mexico, India, British Columbia, particularly in Europe

Plant Part Used

Aerial

Extract

Target Bacteria

Mycobacterium aurum

Assay / Test Done

Microplate Alamar Blue Assay (MABA)

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

4 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Trans - Communic Acid

PubChem ID

637125

Ethnomedicinal Information

Antiseptic properties. In France berries used in treatment of scrofula and chest complaints

PubMed ID [Source Literature]

19755141

Extract Preparation

N/A

Chemical Classification [Active Compound]

Alicyclic, Bicyclic, Terpene, Diterpene, Alkene, Acid

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

302.225

Molecular Formula

C₂₀H₃₀O₂

SMILES

OC(=O)[C@@]1([C@H]2[C@@]([C@H](C(=C)CC2)C/C=C(C)/C=C)(CCC1)C)C

XLogP

6.407

PSA

37.300

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

Curator

Record - 17 of 18 [TOP]

Compound ID	3472
Compound Structure
Plant Source	Juniperus communis Linn. Common Name:
Source Family	Pinaceae
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium tuberculosis H37Ra
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Isoniazid (10 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	1000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information
PubMed ID [Source Literature]	8847882
Extract Preparation
Chemical Classification [Active Compound]
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]
Reference(s)	1) McCutcheon AR, Roberts TE, Gibbons E, Ellis SM, Babiuk LA, Hancock RE, Towers GH.Antiviral screening of British Columbian medicinal plants.J Ethnopharmacol. 1995 Dec 1;49(2):101-10
Curator

Record - 18 of 18 [TOP]

Compound ID	3473
Compound Structure
Plant Source	Juniperus communis Linn. Common Name:
Source Family	Pinaceae
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium smegmatis
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Isoniazid
Inhibition [%]
Activity [MIC] µg/ml	50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	13 - 18 mm (at 50 µl)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information
PubMed ID [Source Literature]	8847882
Extract Preparation
Chemical Classification [Active Compound]
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]
Reference(s)	1) McCutcheon AR, Roberts TE, Gibbons E, Ellis SM, Babiuk LA, Hancock RE, Towers GH.Antiviral screening of British Columbian medicinal plants.J Ethnopharmacol. 1995 Dec 1;49(2):101-10
Curator

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