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                  Page - 1 of 1                  Record - 1 of 7   [TOP]
Compound ID1960
Compound Structure
Plant SourceJuniperus excelsa M. Bieb.     Common Name:Grecian Juniper
Source FamilyCupressaceae
OriginIndia, Saudi Arabia
Plant Part UsedFruit
ExtractHexane
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneMicro Broth Dilution Method
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml15.5 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem IDNR
Ethnomedicinal InformationTuberculosis
PubMed ID [Source Literature]10234860
Extract PreparationN/A
Chemical Classification [Active Compound]N/A
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Reference(s)1) Topçu G, Erenler R, Cakmak O, Johansson CB, Celik C, Chai HB, Pezzuto JM.Diterpenes from the berries of Juniperus excelsa.Phytochemistry. 1999 Apr;50(7):1195-9

2) http://www.pfaf.org/user/Plant.aspx?LatinName=Juniperus+excelsa

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                  Record - 2 of 7   [TOP]
Compound ID1961
Compound Structure
Plant SourceJuniperus excelsa M. Bieb.     Common Name:Grecian Juniper
Source FamilyCupressaceae
OriginIndia, Saudi Arabia
Plant Part UsedFruit
ExtractMethanol
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneMicro Broth Dilution Method
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml17 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem IDNR
Ethnomedicinal InformationTuberculosis
PubMed ID [Source Literature]10234860
Extract PreparationN/A
Chemical Classification [Active Compound]N/A
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Reference(s)1) Topçu G, Erenler R, Cakmak O, Johansson CB, Celik C, Chai HB, Pezzuto JM.Diterpenes from the berries of Juniperus excelsa.Phytochemistry. 1999 Apr;50(7):1195-9

2) http://www.pfaf.org/user/Plant.aspx?LatinName=Juniperus+excelsa

Curator

                  Record - 3 of 7   [TOP]
Compound ID1962
Compound Structure
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Plant SourceJuniperus excelsa M. Bieb.     Common Name:Grecian Juniper
Source FamilyCupressaceae
OriginIndia, Saudi Arabia
Plant Part UsedFruit
Extract
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneMicro Broth Dilution Method
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml14.4 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedJuniperexcelsic acid
PubChem ID   490535
Ethnomedicinal InformationTuberculosis
PubMed ID [Source Literature]10234860
Extract PreparationN/A
Chemical Classification [Active Compound]Alicyclic, Bicyclic, Terpene, Diterpene, Alkene, Acetyl, Acid
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]Against KB cells
Molecular Weight362.246
Molecular FormulaC22H34O4
SMILESO(C1[C@](C2[C@@](C(C(CC2)C)CCC(=C)C=C)(CC1)C)(C)C(=O)O)C(=O)C
XLogP6.661
PSA63.600
H-bond Donor1
H-bond Acceptor4
No. of Rotatable Bond Count7
No. of Rings2
No. of N0
No. of O4
No. of S0
Reference(s)1) Topçu G, Erenler R, Cakmak O, Johansson CB, Celik C, Chai HB, Pezzuto JM.Diterpenes from the berries of Juniperus excelsa.Phytochemistry. 1999 Apr;50(7):1195-9

2) http://www.pfaf.org/user/Plant.aspx?LatinName=Juniperus+excelsa

Curator

                  Record - 4 of 7   [TOP]
Compound ID1963
Compound Structure
DOWNLOAD:
Plant SourceJuniperus excelsa M. Bieb.     Common Name:Grecian Juniper
Source FamilyCupressaceae
OriginIndia, Saudi Arabia
Plant Part UsedFruit
Extract
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneMicro Broth Dilution Method
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml15 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedSandaracopimaric acid
PubChem ID   221580
Ethnomedicinal InformationTuberculosis
PubMed ID [Source Literature]10234860
Extract PreparationN/A
Chemical Classification [Active Compound]Alicyclic, Tricyclic, Terpene, Diterpene, Acid
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]Against KB cells
Molecular Weight302.225
Molecular FormulaC20H30O2
SMILESOC(=O)[C@]1([C@H]2[C@@]([C@@H]3C(=C[C@@](CC3)(C)C=C)CC2)(CCC1)C)C
XLogP6.935
PSA37.300
H-bond Donor1
H-bond Acceptor2
No. of Rotatable Bond Count2
No. of Rings3
No. of N0
No. of O2
No. of S0
Reference(s)1) Topçu G, Erenler R, Cakmak O, Johansson CB, Celik C, Chai HB, Pezzuto JM.Diterpenes from the berries of Juniperus excelsa.Phytochemistry. 1999 Apr;50(7):1195-9

2) http://www.pfaf.org/user/Plant.aspx?LatinName=Juniperus+excelsa

Curator

                  Record - 5 of 7   [TOP]
Compound ID1964
Compound Structure
DOWNLOAD:
Plant SourceJuniperus excelsa M. Bieb.     Common Name:Grecian Juniper
Source FamilyCupressaceae
OriginIndia, Saudi Arabia
Plant Part UsedFruit
Extract
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneMicro Broth Dilution Method
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml6 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedSclareol
PubChem ID   73114
Ethnomedicinal InformationTuberculosis
PubMed ID [Source Literature]10234860
Extract PreparationN/A
Chemical Classification [Active Compound]Alicyclic, Bicyclic, Terpene, Diterpene, Alcohol, Alkene
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]Against KB cells
Molecular Weight308.272
Molecular FormulaC20H36O2
SMILESO[C@]1([C@@H]([C@@]2(C(C(CCC2)(C)C)CC1)C)CC[C@](O)(C)C=C)C
XLogP5.989
PSA40.460
H-bond Donor2
H-bond Acceptor2
No. of Rotatable Bond Count4
No. of Rings2
No. of N0
No. of O2
No. of S0
Reference(s)1) Topçu G, Erenler R, Cakmak O, Johansson CB, Celik C, Chai HB, Pezzuto JM.Diterpenes from the berries of Juniperus excelsa.Phytochemistry. 1999 Apr;50(7):1195-9

2) http://www.pfaf.org/user/Plant.aspx?LatinName=Juniperus+excelsa

Curator

                  Record - 6 of 7   [TOP]
Compound ID1966
Compound Structure
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Plant SourceJuniperus excelsa M. Bieb.     Common Name:Grecian Juniper
Source FamilyCupressaceae
OriginIndia, Saudi Arabia
Plant Part UsedLeaf
ExtractEthanol
Target BacteriaMycobacterium smegmatis
Assay / Test Done
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml32 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified(-) - Sandaracopimaric acid
PubChem ID   221580
Ethnomedicinal InformationTuberculosis
PubMed ID [Source Literature]
Extract PreparationN/A
Chemical Classification [Active Compound]Alicyclic, Tricyclic, Terpene, Diterpene, Acid
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight302.225
Molecular FormulaC20H30O2
SMILESOC(=O)[C@]1([C@H]2[C@@]([C@@H]3C(=C[C@@](CC3)(C)C=C)CC2)(CCC1)C)C
XLogP6.935
PSA37.300
H-bond Donor1
H-bond Acceptor2
No. of Rotatable Bond Count2
No. of Rings3
No. of N0
No. of O2
No. of S0
Reference(s)1) I. Muhammad*, J.S. Mossa, F.S. El-Feraly.Antibacterial diterpenes from the leaves and seeds of Juniperus excelsa M. Bieb.Phytotherapy Research, Volume 6, Issue 5, pages 261–264, September/October 1992

2) http://www.pfaf.org/user/Plant.aspx?LatinName=Juniperus+excelsa

Curator

                  Record - 7 of 7   [TOP]
Compound ID1967
Compound Structure
DOWNLOAD:
Plant SourceJuniperus excelsa M. Bieb.     Common Name:Grecian Juniper
Source FamilyCupressaceae
OriginIndia, Saudi Arabia
Plant Part UsedLeaf
ExtractEthanol
Target BacteriaMycobacterium smegmatis
Assay / Test Done
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/mlNR (inactive)
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedHinokiol
PubChem ID   432946
Ethnomedicinal InformationTuberculosis
PubMed ID [Source Literature]
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Terpene, Meroterpene, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight302.225
Molecular FormulaC20H30O2
SMILESOC1C(C2C(CC1)(c1c(CC2)cc(c(O)c1)C(C)C)C)(C)C
XLogP5.704
PSA40.460
H-bond Donor2
H-bond Acceptor2
No. of Rotatable Bond Count1
No. of Rings3
No. of N0
No. of O2
No. of S0
Reference(s)1) I. Muhammad*, J.S. Mossa, F.S. El-Feraly.Antibacterial diterpenes from the leaves and seeds of Juniperus excelsa M. Bieb.Phytotherapy Research, Volume 6, Issue 5, pages 261–264, September/October 1992

2) http://www.pfaf.org/user/Plant.aspx?LatinName=Juniperus+excelsa

Curator


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