| Compound ID | 2022 |
| Compound Structure | |
| Plant Source | Leptadenia reticulata Wt.and Arn. syn. Asclepias tuberosa Roxb. Common Name:Jivanti, Jivaniya, Jivapushpa (Sanskrit) |
| Source Family | Asclepiadaceae |
| Origin | India |
| Plant Part Used | Mother tinture |
| Extract | Ethanol |
| Target Bacteria | Mycobacterium tuberculosis H37Rv (human) |
| Assay / Test Done | Tube Dilution Test |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | 1:40 dilution |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis, asthma, cough, random screening |
| PubMed ID [Source Literature] | 2118130 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Grange, J.M., Davey, R.W., 1990. Detection of antituberculous activity in plant extracts. Journal of Applied Bacteriology 68, 587–591
|
| Curator | |
| Compound ID | 2023 |
| Compound Structure | |
| Plant Source | Leptadenia reticulata Wt.and Arn. syn. Asclepias tuberosa Roxb. Common Name:Jivanti, Jivaniya, Jivapushpa (Sanskrit) |
| Source Family | Asclepiadaceae |
| Origin | India |
| Plant Part Used | Leaf |
| Extract | Water |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | Broth Dilution Assay |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | 1:160 dilution |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis, asthma, cough, random screening |
| PubMed ID [Source Literature] | 17276637 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
2) Sharma, P.K., Dhyani, S.K., Shanker,V., 1979. Some useful and medicinal plants of the district Dehradun and Siwalik. Journal of Science Research in Plant Medicine 1, 17–43.
|
| Curator | |
| Compound ID | 2024 |
| Compound Structure | |
| Plant Source | Leptadenia reticulata Wt.and Arn. syn. Asclepias tuberosa Roxb. Common Name:Jivanti, Jivaniya, Jivapushpa (Sanskrit) |
| Source Family | Asclepiadaceae |
| Origin | India |
| Plant Part Used | Root |
| Extract | Water |
| Target Bacteria | Mycobacterium tuberculosis |
| Assay / Test Done | Broth Dilution Assay |
| Positive Control Used (conc.) | |
| Inhibition [%] | |
| Activity [MIC] µg/ml | |
| Activity (In terms of dilution) | 1:80 dilution |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis, asthma, cough, random screening |
| PubMed ID [Source Literature] | 17276637 |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
2) Sharma, P.K., Dhyani, S.K., Shanker,V., 1979. Some useful and medicinal plants of the district Dehradun and Siwalik. Journal of Science Research in Plant Medicine 1, 17–43.
|
| Curator | |
| Compound ID | 2025 |
| Compound Structure | |
| Plant Source | Leptadenia reticulata Wt.and Arn. syn. Asclepias tuberosa Roxb. Common Name:Jivanti, Jivaniya, Jivapushpa (Sanskrit) |
| Source Family | Asclepiadaceae |
| Origin | India |
| Plant Part Used | Whole plant |
| Extract | Cyclohexane |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | Agar - Well Diffusion Assay |
| Positive Control Used (conc.) | Streptomycin sulphate (1 mg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | 2 mm, 20 mm (control) |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis, asthma, cough, random screening |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) James D. Mcchesney, Robert P. Adams.Co-evaluation of plant extracts as petrochemical substitutes and for biologically active compounds.Economic Botany. 12/1984, 39(1):74-86
|
| Curator | |
| Compound ID | 2026 |
| Compound Structure | |
| Plant Source | Leptadenia reticulata Wt.and Arn. syn. Asclepias tuberosa Roxb. Common Name:Jivanti, Jivaniya, Jivapushpa (Sanskrit) |
| Source Family | Asclepiadaceae |
| Origin | India |
| Plant Part Used | Whole plant |
| Extract | Water |
| Target Bacteria | Mycobacterium smegmatis |
| Assay / Test Done | Agar - Well Diffusion Assay |
| Positive Control Used (conc.) | Streptomycin sulphate (1 mg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 2000 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | 1 mm, 20 mm (control) |
| Active Compound Identified | |
| PubChem ID | NR |
| Ethnomedicinal Information | Tuberculosis, asthma, cough, random screening |
| PubMed ID [Source Literature] | |
| Extract Preparation | N/A |
| Chemical Classification [Active Compound] | N/A |
| Media / Broth Used [Antimicrobial Assay/Test] | N/A |
| Cytotoxicity Assay [AID] | N/A |
| Reference(s) | 1) James D. Mcchesney, Robert P. Adams.Co-evaluation of plant extracts as petrochemical substitutes and for biologically active compounds.Economic Botany. 12/1984, 39(1):74-86
|
| Curator | |
