BioPhytMol: A database of Phytomolecules against Mycobacteria

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Page - 1 of 1 Record - 1 of 10 [TOP]

Compound ID	2119
Compound Structure
Plant Source	Mallotus philippensis (Linn.) Muell Arg. Common Name:Kamala Tree (English), Kampillaka, Kampilla, Karkash, Raktaanga, Rechan (Sanskrit)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Bark
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol (300 mg/ml)
Inhibition [%]
Activity [MIC] µg/ml	300000 µg/ml of dried plant material
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, bronchitis, random screening, antihelmentic
PubMed ID [Source Literature]	8866730
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Edel F, Manandhar NP, Towers GH.Antimicrobial activities of southern Nepalese medicinal plants.J Ethnopharmacol. 1996 Feb;50(2):97-102
Curator

Record - 2 of 10 [TOP]

Compound ID	2120
Compound Structure
Plant Source	Mallotus philippensis (Linn.) Muell Arg. Common Name:Kamala Tree (English), Kampillaka, Kampilla, Karkash, Raktaanga, Rechan (Sanskrit)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Mother tinture
Extract	Ethanol (95 %)
Target Bacteria	Mycobacterium tuberculosis H37Rv (human)
Assay / Test Done	Tube Dilution Test
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)	1:40 dilution
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, bronchitis, random screening, antihelmentic
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Grange, J.M., Davey, R.W., 1990. Detection of antituberculous activity in plant extracts. Journal of Applied Bacteriology 68, 587–591 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India
Curator

Record - 3 of 10 [TOP]

Compound ID	2121
Compound Structure
Plant Source	Mallotus philippensis (Linn.) Muell Arg. Common Name:Kamala Tree (English), Kampillaka, Kampilla, Karkash, Raktaanga, Rechan (Sanskrit)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Leaf
Extract	Hexane
Target Bacteria	Mycobacterium smegmatis (MTCC 6)
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Rifampin (5.0 µg/Disc)
Inhibition [%]
Activity [MIC] µg/ml	500 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, bronchitis, random screening, antihelmentic
PubMed ID [Source Literature]	21114505
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta VK, Shukla C, Bisht GR, Saikia D, Kumar S, Thakur RL.Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay.Lett Appl Microbiol. 2011 Jan;52(1):33-40
Curator

Record - 4 of 10 [TOP]

Compound ID	2122
Compound Structure
Plant Source	Mallotus philippensis (Linn.) Muell Arg. Common Name:Kamala Tree (English), Kampillaka, Kampilla, Karkash, Raktaanga, Rechan (Sanskrit)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Leaf
Extract	Hexane
Target Bacteria	Mycobacterium smegmatis (MTCC 994)
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Rifampin (5.0 µg/Disc)
Inhibition [%]
Activity [MIC] µg/ml	50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, bronchitis, random screening, antihelmentic
PubMed ID [Source Literature]	21114505
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta VK, Shukla C, Bisht GR, Saikia D, Kumar S, Thakur RL.Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay.Lett Appl Microbiol. 2011 Jan;52(1):33-40
Curator

Record - 5 of 10 [TOP]

Compound ID	2123
Compound Structure
Plant Source	Mallotus philippensis (Linn.) Muell Arg. Common Name:Kamala Tree (English), Kampillaka, Kampilla, Karkash, Raktaanga, Rechan (Sanskrit)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Leaf
Extract	Ethyl acetate
Target Bacteria	Mycobacterium smegmatis (MTCC 6)
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Rifampin (5.0 µg/Disc)
Inhibition [%]
Activity [MIC] µg/ml	125 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, bronchitis, random screening, antihelmentic
PubMed ID [Source Literature]	21114505
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta VK, Shukla C, Bisht GR, Saikia D, Kumar S, Thakur RL.Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay.Lett Appl Microbiol. 2011 Jan;52(1):33-40
Curator

Record - 6 of 10 [TOP]

Compound ID	2124
Compound Structure
Plant Source	Mallotus philippensis (Linn.) Muell Arg. Common Name:Kamala Tree (English), Kampillaka, Kampilla, Karkash, Raktaanga, Rechan (Sanskrit)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Leaf
Extract	Ethyl acetate
Target Bacteria	Mycobacterium smegmatis (MTCC 994)
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Rifampin (5.0 µg/Disc)
Inhibition [%]
Activity [MIC] µg/ml	250 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, bronchitis, random screening, antihelmentic
PubMed ID [Source Literature]	21114505
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta VK, Shukla C, Bisht GR, Saikia D, Kumar S, Thakur RL.Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay.Lett Appl Microbiol. 2011 Jan;52(1):33-40
Curator

Record - 7 of 10 [TOP]

Compound ID	2125
Compound Structure
Plant Source	Mallotus philippensis (Linn.) Muell Arg. Common Name:Kamala Tree (English), Kampillaka, Kampilla, Karkash, Raktaanga, Rechan (Sanskrit)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Leaf
Extract	Chloroform
Target Bacteria	Mycobacterium smegmatis (MTCC 6)
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Rifampin (5.0 µg/Disc)
Inhibition [%]
Activity [MIC] µg/ml	50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, bronchitis, random screening, antihelmentic
PubMed ID [Source Literature]	21114505
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta VK, Shukla C, Bisht GR, Saikia D, Kumar S, Thakur RL.Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay.Lett Appl Microbiol. 2011 Jan;52(1):33-40
Curator

Record - 8 of 10 [TOP]

Compound ID	2126
Compound Structure
Plant Source	Mallotus philippensis (Linn.) Muell Arg. Common Name:Kamala Tree (English), Kampillaka, Kampilla, Karkash, Raktaanga, Rechan (Sanskrit)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Leaf
Extract	Chloroform
Target Bacteria	Mycobacterium smegmatis (MTCC 994)
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Rifampin (5.0 µg/Disc)
Inhibition [%]
Activity [MIC] µg/ml	250 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, bronchitis, random screening, antihelmentic
PubMed ID [Source Literature]	21114505
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta VK, Shukla C, Bisht GR, Saikia D, Kumar S, Thakur RL.Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay.Lett Appl Microbiol. 2011 Jan;52(1):33-40
Curator

Record - 9 of 10 [TOP]

Compound ID	2127
Compound Structure
Plant Source	Mallotus philippensis (Linn.) Muell Arg. Common Name:Kamala Tree (English), Kampillaka, Kampilla, Karkash, Raktaanga, Rechan (Sanskrit)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Leaf
Extract	Ethanol
Target Bacteria	Mycobacterium tuberculosis H37Ra
Assay / Test Done	Radiometric assay using BACTEC 460 system
Positive Control Used (conc.)	Rifampin (0.5 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, bronchitis, random screening, antihelmentic
PubMed ID [Source Literature]	21114505
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta VK, Shukla C, Bisht GR, Saikia D, Kumar S, Thakur RL.Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay.Lett Appl Microbiol. 2011 Jan;52(1):33-40
Curator

Record - 10 of 10 [TOP]

Compound ID	2128
Compound Structure
Plant Source	Mallotus philippensis (Linn.) Muell Arg. Common Name:Kamala Tree (English), Kampillaka, Kampilla, Karkash, Raktaanga, Rechan (Sanskrit)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Leaf
Extract	Ethanol
Target Bacteria	Mycobacterium tuberculosis H37Rv
Assay / Test Done	Radiometric assay using BACTEC 460 system
Positive Control Used (conc.)	Rifampin (1 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	500 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, bronchitis, random screening, antihelmentic
PubMed ID [Source Literature]	21114505
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta VK, Shukla C, Bisht GR, Saikia D, Kumar S, Thakur RL.Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay.Lett Appl Microbiol. 2011 Jan;52(1):33-40
Curator

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