BioPhytMol: A database of Phytomolecules against Mycobacteria

| Home |

Similarity

One to One

Anti-TB Drugs

One to Many

Anti-TB Drugs

Page - 1 of 1 Record - 1 of 5 [TOP]

Compound ID	2738
Compound Structure
Plant Source	Trichilia dregeana Harv. & Sond. Common Name:Forest Mahogany, Forest Natal Mahogany, Cape Mahogany, Thunder Tree, Christmas Bells, Red Ash
Source Family	Meliaceae
Origin	Africa
Plant Part Used	Leaf
Extract	Ethyl acetate
Target Bacteria	Mycobacterium aurum A+
Assay / Test Done	Broth Microdilution Method (BMM)
Positive Control Used (conc.)	Ciprofloxacin (1.8 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	6250 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Gonorrhea, fever, diarrhoea, pain in the back and as a purgative
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Eldeen, I.M.S., Van Staden, J., 2007. Antimycobacterial activity of some trees used in South African traditional medicine. South African Journal of Botany 73, 248–25 2) http://database.prota.org/PROTAhtml/Trichilia%20dregeana_En.htm
Curator

Record - 2 of 5 [TOP]

Compound ID	2739
Compound Structure
Plant Source	Trichilia dregeana Harv. & Sond. Common Name:Forest Mahogany, Forest Natal Mahogany, Cape Mahogany, Thunder Tree, Christmas Bells, Red Ash
Source Family	Meliaceae
Origin	Africa
Plant Part Used	Leaf
Extract	Ethanol
Target Bacteria	Mycobacterium aurum A+
Assay / Test Done	Broth Microdilution Method (BMM)
Positive Control Used (conc.)	Ciprofloxacin (1.8 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	780 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Gonorrhea, fever, diarrhoea, pain in the back and as a purgative
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Eldeen, I.M.S., Van Staden, J., 2007. Antimycobacterial activity of some trees used in South African traditional medicine. South African Journal of Botany 73, 248–25 2) http://database.prota.org/PROTAhtml/Trichilia%20dregeana_En.htm
Curator

Record - 3 of 5 [TOP]

Compound ID	2740
Compound Structure
Plant Source	Trichilia dregeana Harv. & Sond. Common Name:Forest Mahogany, Forest Natal Mahogany, Cape Mahogany, Thunder Tree, Christmas Bells, Red Ash
Source Family	Meliaceae
Origin	Africa
Plant Part Used	Bark
Extract	Ethanol
Target Bacteria	Mycobacterium aurum A+
Assay / Test Done	Broth Microdilution Method (BMM)
Positive Control Used (conc.)	Ciprofloxacin (1.8 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	1560 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Gonorrhea, fever, diarrhoea, pain in the back and as a purgative
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Eldeen, I.M.S., Van Staden, J., 2007. Antimycobacterial activity of some trees used in South African traditional medicine. South African Journal of Botany 73, 248–25 2) http://database.prota.org/PROTAhtml/Trichilia%20dregeana_En.htm
Curator

Record - 4 of 5 [TOP]

Compound ID	2741
Compound Structure
Plant Source	Trichilia dregeana Harv. & Sond. Common Name:Forest Mahogany, Forest Natal Mahogany, Cape Mahogany, Thunder Tree, Christmas Bells, Red Ash
Source Family	Meliaceae
Origin	Africa
Plant Part Used	Root
Extract	Dichloromethane
Target Bacteria	Mycobacterium aurum A+
Assay / Test Done	Broth Microdilution Method (BMM)
Positive Control Used (conc.)	Ciprofloxacin (1.8 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	3120 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Gonorrhea, fever, diarrhoea, pain in the back and as a purgative
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Eldeen, I.M.S., Van Staden, J., 2007. Antimycobacterial activity of some trees used in South African traditional medicine. South African Journal of Botany 73, 248–25 2) http://database.prota.org/PROTAhtml/Trichilia%20dregeana_En.htm
Curator

Record - 5 of 5 [TOP]

Compound ID	2742
Compound Structure
Plant Source	Trichilia dregeana Harv. & Sond. Common Name:Forest Mahogany, Forest Natal Mahogany, Cape Mahogany, Thunder Tree, Christmas Bells, Red Ash
Source Family	Meliaceae
Origin	Africa
Plant Part Used	Root
Extract	Ethanol
Target Bacteria	Mycobacterium aurum A+
Assay / Test Done	Broth Microdilution Method (BMM)
Positive Control Used (conc.)	Ciprofloxacin (1.8 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	6250 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Gonorrhea, fever, diarrhoea, pain in the back and as a purgative
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Eldeen, I.M.S., Van Staden, J., 2007. Antimycobacterial activity of some trees used in South African traditional medicine. South African Journal of Botany 73, 248–25 2) http://database.prota.org/PROTAhtml/Trichilia%20dregeana_En.htm
Curator

Developed by: CSIR- OSDD Unit, Delhi, India and Hosted by: Bioinformatics Centre, Institute of Microbial Technology, Sec-39A, Chandigarh, India.
The website has been tested on the latest version of Google Chrome (34.0.1847.137 m) and Mozilla Firefox (29.0.1)