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Compound ID2368
Compound Structure
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Plant SourcePiper bogotense     Common Name:
Source FamilyPiperaceae
OriginColombia
Plant Part UsedLeaf
ExtractEssential oil (0.2 %)
Target BacteriaMycobacterium tuberculosis H37Rv
Assay / Test DoneMacrodilution method in glass tubes
Positive Control Used (conc.)Rifampin (0.50 µg/ml), Isoniazid (0.03 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml130 ± 95 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identifiedβ - Phellandrene
PubChem ID   11142
Ethnomedicinal InformationTuberculosis
PubMed ID [Source Literature]19753839
Extract PreparationN/A
Chemical Classification [Active Compound]Alicyclic, Terpene, Monoterpene
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight136.125
Molecular FormulaC10H16
SMILESC1(C(C)C)CCC(=C)C=C1
XLogP4.472
PSA0.000
H-bond Donor0
H-bond Acceptor0
No. of Rotatable Bond Count1
No. of Rings1
No. of N0
No. of O0
No. of S0
Reference(s)1) Bueno-Sánchez JG, Martínez-Morales JR, Stashenko EE, Ribón W.Anti-tubercular activity of eleven aromatic and medicinal plants occurring in Colombia.Biomedica. 2009 Mar;29(1):51-60

Curator


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