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Compound ID3392
Compound Structure
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Plant SourceErythrina gibbosa     Common Name:NR
Source FamilyFabaceae
OriginPanamanian
Plant Part UsedNR
ExtractNR
Target BacteriaMycobacterium tuberculosis H37Rv
Assay / Test DoneAgar Dilution - Streak Assay
Positive Control Used (conc.)NR
Inhibition [%]NR
Activity [MIC] µg/ml8 - 25 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedPhaseolidine
PubChem ID   119268
Ethnomedicinal InformationNR
PubMed ID [Source Literature]9828037
Extract PreparationNR
Chemical Classification [Active Compound]Aromatic, Tetracyclic, Benzopyran, Benzofuranoid, Prenylated
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]NR
Molecular Weight324.136
Molecular FormulaC20H20O4
SMILESO1[C@@H]2[C@H](c3c1c(c(O)cc3)CC=C(C)C)COc1c2ccc(O)c1
XLogP3.265
PSA58.920
H-bond Donor2
H-bond Acceptor4
No. of Rotatable Bond Count2
No. of Rings4
No. of N0
No. of O4
No. of S0
Reference(s)1) Mitscher LA, Baker W.Tuberculosis: a search for novel therapy starting with natural products.Med Res Rev. 1998 Nov;18(6):363-74

CuratorWvarsha, keyamukherjee, rachanake


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