| Compound ID | 3678 |
| Compound Structure |  |
| Plant Source | Evodia rutaecarpa (Juss.) Benth. Common Name: |
| Source Family | Rutaceae |
| Origin | |
| Plant Part Used | Unripe Fruit |
| Extract | N - hexane |
| Target Bacteria | Mycobacterium fortuitum (ATCC 6841) |
| Assay / Test Done | |
| Positive Control Used (conc.) | Ethambutol (16 µg/ml), Isoniazid (2 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 32 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | 1 - Methyl - 4 - Methylidene - 2 - Tetradecyl - 1, 4 - Dihydroquinoline |
| PubChem ID | NR |
| Ethnomedicinal Information | |
| PubMed ID [Source Literature] | 16051468 |
| Extract Preparation | |
| Chemical Classification [Active Compound] | Aromatic, Bicyclic, Alkaloid, Quinolone, Ketone |
| Media / Broth Used [Antimicrobial Assay/Test] | |
| Cytotoxicity Assay [AID] | |
| Molecular Weight | 313.241 |
| Molecular Formula | C21H31NO |
| SMILES | C1cccc2c1n(c(cc2=O)CCCCCCCCCCC)C |
| XLogP | 7.530 |
| PSA | 17.070 |
| H-bond Donor | 0 |
| H-bond Acceptor | 1 |
| No. of Rotatable Bond Count | 10 |
| No. of Rings | 2 |
| No. of N | 1 |
| No. of O | 1 |
| No. of S | 0 |
| Reference(s) | 1) Adams M, Wube AA, Bucar F, Bauer R, Kunert O, Haslinger E.Quinolone alkaloids from Evodia rutaecarpa: a potent new group of antimycobacterial compounds.Int J Antimicrob Agents. 2005 Sep;26(3):262-4
|
| Curator | Vsheeba, vikramjitmandal |
| Compound ID | 3683 |
| Compound Structure | |
| Plant Source | Evodia rutaecarpa (Juss.) Benth. Common Name: |
| Source Family | Rutaceae |
| Origin | |
| Plant Part Used | Unripe Fruit |
| Extract | N - hexane |
| Target Bacteria | Mycobacterium smegmatis (ATCC 19429) |
| Assay / Test Done | |
| Positive Control Used (conc.) | Ethambutol (1 µg/ml), Isoniazid (4 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 8 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | 1 - Methyl - 4 - Methylidene - 2 - Tetradecyl - 1, 4 - Dihydroquinoline |
| PubChem ID | NR |
| Ethnomedicinal Information | |
| PubMed ID [Source Literature] | 16051468 |
| Extract Preparation | |
| Chemical Classification [Active Compound] | Aromatic, Bicyclic, Alkaloid, Quinolone, Ketone |
| Media / Broth Used [Antimicrobial Assay/Test] | |
| Cytotoxicity Assay [AID] | |
| Molecular Weight | 313.241 |
| Molecular Formula | C21H31NO |
| SMILES | C1cccc2c1n(c(cc2=O)CCCCCCCCCCC)C |
| XLogP | 7.530 |
| PSA | 17.070 |
| H-bond Donor | 0 |
| H-bond Acceptor | 1 |
| No. of Rotatable Bond Count | 10 |
| No. of Rings | 2 |
| No. of N | 1 |
| No. of O | 1 |
| No. of S | 0 |
| Reference(s) | 1) Adams M, Wube AA, Bucar F, Bauer R, Kunert O, Haslinger E.Quinolone alkaloids from Evodia rutaecarpa: a potent new group of antimycobacterial compounds.Int J Antimicrob Agents. 2005 Sep;26(3):262-4
|
| Curator | Vsheeba, vikramjitmandal |
| Compound ID | 3688 |
| Compound Structure | |
| Plant Source | Evodia rutaecarpa (Juss.) Benth. Common Name: |
| Source Family | Rutaceae |
| Origin | |
| Plant Part Used | Unripe Fruit |
| Extract | N - hexane |
| Target Bacteria | Mycobacterium phlei (ATCC 19249) |
| Assay / Test Done | |
| Positive Control Used (conc.) | Ethambutol (2 µg/ml), Isoniazid (4 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | 2 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | 1 - Methyl - 4 - Methylidene - 2 - Tetradecyl - 1, 4 - Dihydroquinoline |
| PubChem ID | NR |
| Ethnomedicinal Information | |
| PubMed ID [Source Literature] | 16051468 |
| Extract Preparation | |
| Chemical Classification [Active Compound] | Aromatic, Bicyclic, Alkaloid, Quinolone, Ketone |
| Media / Broth Used [Antimicrobial Assay/Test] | |
| Cytotoxicity Assay [AID] | |
| Molecular Weight | 313.241 |
| Molecular Formula | C21H31NO |
| SMILES | C1cccc2c1n(c(cc2=O)CCCCCCCCCCC)C |
| XLogP | 7.530 |
| PSA | 17.070 |
| H-bond Donor | 0 |
| H-bond Acceptor | 1 |
| No. of Rotatable Bond Count | 10 |
| No. of Rings | 2 |
| No. of N | 1 |
| No. of O | 1 |
| No. of S | 0 |
| Reference(s) | 1) Adams M, Wube AA, Bucar F, Bauer R, Kunert O, Haslinger E.Quinolone alkaloids from Evodia rutaecarpa: a potent new group of antimycobacterial compounds.Int J Antimicrob Agents. 2005 Sep;26(3):262-4
|
| Curator | Vsheeba, vikramjitmandal |
