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                  Page - 1 of 1                  Record - 1 of 4   [TOP]
Compound ID1261
Compound Structure
DOWNLOAD:
Plant SourceBocconia arborea     Common Name:Bocconia
Source FamilyPapaveraceae
OriginMexico
Plant Part UsedAerial
Extract
Target BacteriaMycobacterium tuberculosis H37Rv
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Isoniazid (0.06 µg/ml), Ethambutol (2 µg/ml), Rifampin (0.06 µg/ml), Streptomycin (0.50 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified6 - Methoxydihydrosanguinarine
PubChem ID   14847270
Ethnomedicinal InformationTuberculosis
PubMed ID [Source Literature]
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tetracyclic, Alkaloid, Benzophenanthridine, Quinoline, Ether
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight363.111
Molecular FormulaC21H17NO5
SMILESO(C1N(c2c(c3c1c1OCOc1cc3)ccc1c2cc2OCOc2c1)C)C
XLogP3.143
PSA49.390
H-bond Donor0
H-bond Acceptor6
No. of Rotatable Bond Count1
No. of Rings6
No. of N1
No. of O5
No. of S0
Reference(s)1) María del Rayo Camacho-Corona, Juan Manuel de Jesús Favela-Hernández, Omar González-Santiago, Elvira Garza-González, Gloria María Molina-Salinas, Salvador Said-Fernández, Guillermo Delgado, Julieta Luna-Herrerae.Evaluation of Some Plant-derived Secondary Metabolites Against Sensitive and Multidrug-resistant Mycobacterium tuberculosis.J. Mex. Chem. Soc. 2009, 53(2), 71-75

2) http://zipcodezoo.com/Plants/B/Bocconia_arborea/

Curator

                  Record - 2 of 4   [TOP]
Compound ID1266
Compound Structure
DOWNLOAD:
Plant SourceBocconia arborea     Common Name:Bocconia
Source FamilyPapaveraceae
OriginMexico
Plant Part UsedAerial
Extract
Target BacteriaMycobacterium tuberculosis (345)
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Streptomycin (3.125 µg/ml), Isoniazid (< 50 µg/ml), Ethambutol (12.50 µg/ml), Rifampin (< 50 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml25 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified6 - Methoxydihydrosanguinarine
PubChem ID   14847270
Ethnomedicinal InformationTuberculosis
PubMed ID [Source Literature]
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tetracyclic, Alkaloid, Benzophenanthridine, Quinoline, Ether
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight363.111
Molecular FormulaC21H17NO5
SMILESO(C1N(c2c(c3c1c1OCOc1cc3)ccc1c2cc2OCOc2c1)C)C
XLogP3.143
PSA49.390
H-bond Donor0
H-bond Acceptor6
No. of Rotatable Bond Count1
No. of Rings6
No. of N1
No. of O5
No. of S0
Reference(s)1) María del Rayo Camacho-Corona, Juan Manuel de Jesús Favela-Hernández, Omar González-Santiago, Elvira Garza-González, Gloria María Molina-Salinas, Salvador Said-Fernández, Guillermo Delgado, Julieta Luna-Herrerae.Evaluation of Some Plant-derived Secondary Metabolites Against Sensitive and Multidrug-resistant Mycobacterium tuberculosis.J. Mex. Chem. Soc. 2009, 53(2), 71-75

2) http://zipcodezoo.com/Plants/B/Bocconia_arborea/

Curator

                  Record - 3 of 4   [TOP]
Compound ID1271
Compound Structure
DOWNLOAD:
Plant SourceBocconia arborea     Common Name:Bocconia
Source FamilyPapaveraceae
OriginMexico
Plant Part UsedAerial
Extract
Target BacteriaMycobacterium tuberculosis (M12)
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Streptomycin (12.50 µg/ml), Isoniazid (< 50 µg/ml), Ethambutol (12.50 µg/ml), Rifampin (< 50 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified6 - Methoxydihydrosanguinarine
PubChem ID   14847270
Ethnomedicinal InformationTuberculosis
PubMed ID [Source Literature]
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tetracyclic, Alkaloid, Benzophenanthridine, Quinoline, Ether
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight363.111
Molecular FormulaC21H17NO5
SMILESO(C1N(c2c(c3c1c1OCOc1cc3)ccc1c2cc2OCOc2c1)C)C
XLogP3.143
PSA49.390
H-bond Donor0
H-bond Acceptor6
No. of Rotatable Bond Count1
No. of Rings6
No. of N1
No. of O5
No. of S0
Reference(s)1) María del Rayo Camacho-Corona, Juan Manuel de Jesús Favela-Hernández, Omar González-Santiago, Elvira Garza-González, Gloria María Molina-Salinas, Salvador Said-Fernández, Guillermo Delgado, Julieta Luna-Herrerae.Evaluation of Some Plant-derived Secondary Metabolites Against Sensitive and Multidrug-resistant Mycobacterium tuberculosis.J. Mex. Chem. Soc. 2009, 53(2), 71-75

2) http://zipcodezoo.com/Plants/B/Bocconia_arborea/

Curator

                  Record - 4 of 4   [TOP]
Compound ID1276
Compound Structure
DOWNLOAD:
Plant SourceBocconia arborea     Common Name:Bocconia
Source FamilyPapaveraceae
OriginMexico
Plant Part UsedAerial
Extract
Target BacteriaMycobacterium tuberculosis (M20)
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)Streptomycin (25 µg/ml), Isoniazid (< 50 µg/ml), Ethambutol (12.50 µg/ml), Rifampin (< 50 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml12.5 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified6 - Methoxydihydrosanguinarine
PubChem ID   14847270
Ethnomedicinal InformationTuberculosis
PubMed ID [Source Literature]
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tetracyclic, Alkaloid, Benzophenanthridine, Quinoline, Ether
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight363.111
Molecular FormulaC21H17NO5
SMILESO(C1N(c2c(c3c1c1OCOc1cc3)ccc1c2cc2OCOc2c1)C)C
XLogP3.143
PSA49.390
H-bond Donor0
H-bond Acceptor6
No. of Rotatable Bond Count1
No. of Rings6
No. of N1
No. of O5
No. of S0
Reference(s)1) María del Rayo Camacho-Corona, Juan Manuel de Jesús Favela-Hernández, Omar González-Santiago, Elvira Garza-González, Gloria María Molina-Salinas, Salvador Said-Fernández, Guillermo Delgado, Julieta Luna-Herrerae.Evaluation of Some Plant-derived Secondary Metabolites Against Sensitive and Multidrug-resistant Mycobacterium tuberculosis.J. Mex. Chem. Soc. 2009, 53(2), 71-75

2) http://zipcodezoo.com/Plants/B/Bocconia_arborea/

Curator


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