|  Home  |Search   |  Browse  |Similarity   |Data Visualization  |Submission  |Contact Us  |  













                  Page - 1 of 1                  Record - 1 of 3   [TOP]
Compound ID3367
Compound Structure
DOWNLOAD:
Plant SourceCanella winterana     Common Name:NR
Source FamilyCanellaceae
OriginGuadeloupe
Plant Part UsedNR
ExtractNR
Target BacteriaMycobacterium tuberculosis H37Rv
Assay / Test DoneNR
Positive Control Used (conc.)NR
Inhibition [%]NR
Activity [MIC] µg/mlBactec: 100 µg/ml, 7H11 agar: 200 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedCanellal
PubChem ID   325604
Ethnomedicinal InformationAntimycobacterial
PubMed ID [Source Literature]9626931
Extract PreparationThe dried powdered material was moistened with 25 % NH4OH, and extracted by chloroform. The organic phase was treated with 2 % HCl, the acid layer was washed with petroleum ether, basified with 25 % NH4OH, and extracted with chloroform. The organic phase was washed with water, and dried over Na2SO4. The organic extracts were evaporated and subjected to chromatography on silica gel
Chemical Classification [Active Compound]Alicyclic, Bicyclic, Terpene, Sesquiterpene, Aldehyde, Alcohol
Media / Broth Used [Antimicrobial Assay/Test]Fresh Loëwenstein - Jensen (LJ) slants, Middlebrook 7H11 agar medium
Cytotoxicity Assay [AID]NR
Molecular Weight248.141
Molecular FormulaC15H20O3
SMILESOC1(C2(C(C(=C)C(CC2)C)CC=C1C=O)C)C=O
XLogP2.567
PSA54.370
H-bond Donor1
H-bond Acceptor3
No. of Rotatable Bond Count2
No. of Rings2
No. of N0
No. of O3
No. of S0
Reference(s)1) Rastogi N, Abaul J, Goh KS, Devallois A, Philogène E, Bourgeois P.Antimycobacterial activity of chemically defined natural substances from the Caribbean flora in Guadeloupe.FEMS Immunol Med Microbiol. 1998 Apr;20(4):267-73

CuratorWvarsha, rachanake

                  Record - 2 of 3   [TOP]
Compound ID3368
Compound Structure
DOWNLOAD:
Plant SourceCanella winterana     Common Name:NR
Source FamilyCanellaceae
OriginGuadeloupe
Plant Part UsedNR
ExtractNR
Target BacteriaMycobacterium avium 733
Assay / Test DoneNR
Positive Control Used (conc.)NR
Inhibition [%]NR
Activity [MIC] µg/mlBactec: > 100 µg/ml, 7H11 agar: > 200 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedCanellal
PubChem ID   325604
Ethnomedicinal InformationAntimycobacterial
PubMed ID [Source Literature]9626931
Extract PreparationThe dried powdered material was moistened with 25 % NH4OH, and extracted by chloroform. The organic phase was treated with 2 % HCl, the acid layer was washed with petroleum ether, basified with 25 % NH4OH, and extracted with chloroform. The organic phase was washed with water, and dried over Na2SO4. The organic extracts were evaporated and subjected to chromatography on silica gel
Chemical Classification [Active Compound]Alicyclic, Bicyclic, Terpene, Sesquiterpene, Aldehyde, Alcohol
Media / Broth Used [Antimicrobial Assay/Test]Fresh Loëwenstein - Jensen (LJ) slants, Middlebrook 7H11 agar medium
Cytotoxicity Assay [AID]NR
Molecular Weight248.141
Molecular FormulaC15H20O3
SMILESOC1(C2(C(C(=C)C(CC2)C)CC=C1C=O)C)C=O
XLogP2.567
PSA54.370
H-bond Donor1
H-bond Acceptor3
No. of Rotatable Bond Count2
No. of Rings2
No. of N0
No. of O3
No. of S0
Reference(s)1) Rastogi N, Abaul J, Goh KS, Devallois A, Philogène E, Bourgeois P.Antimycobacterial activity of chemically defined natural substances from the Caribbean flora in Guadeloupe.FEMS Immunol Med Microbiol. 1998 Apr;20(4):267-73

CuratorWvarsha, rachanake

                  Record - 3 of 3   [TOP]
Compound ID3369
Compound Structure
DOWNLOAD:
Plant SourceCanella winterana     Common Name:NR
Source FamilyCanellaceae
OriginGuadeloupe
Plant Part UsedNR
ExtractNR
Target BacteriaMycobacterium kansasii (Clinical isolate 94 - 069)
Assay / Test DoneNR
Positive Control Used (conc.)NR
Inhibition [%]NR
Activity [MIC] µg/mlBactec: 100 µg/ml, 7H11 agar: 200 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedCanellal
PubChem ID   325604
Ethnomedicinal InformationAntimycobacterial
PubMed ID [Source Literature]9626931
Extract PreparationThe dried powdered material was moistened with 25 % NH4OH, and extracted by chloroform. The organic phase was treated with 2 % HCl, the acid layer was washed with petroleum ether, basified with 25 % NH4OH, and extracted with chloroform. The organic phase was washed with water, and dried over Na2SO4. The organic extracts were evaporated and subjected to chromatography on silica gel
Chemical Classification [Active Compound]Alicyclic, Bicyclic, Terpene, Sesquiterpene, Aldehyde, Alcohol
Media / Broth Used [Antimicrobial Assay/Test]Fresh Loëwenstein - Jensen (LJ) slants, Middlebrook 7H11 agar medium
Cytotoxicity Assay [AID]NR
Molecular Weight248.141
Molecular FormulaC15H20O3
SMILESOC1(C2(C(C(=C)C(CC2)C)CC=C1C=O)C)C=O
XLogP2.567
PSA54.370
H-bond Donor1
H-bond Acceptor3
No. of Rotatable Bond Count2
No. of Rings2
No. of N0
No. of O3
No. of S0
Reference(s)1) Rastogi N, Abaul J, Goh KS, Devallois A, Philogène E, Bourgeois P.Antimycobacterial activity of chemically defined natural substances from the Caribbean flora in Guadeloupe.FEMS Immunol Med Microbiol. 1998 Apr;20(4):267-73

CuratorWvarsha, rachanake


Developed by: CSIR- OSDD Unit, Delhi, India and Hosted by: Bioinformatics Centre,   Institute of Microbial Technology, Sec-39A, Chandigarh, India.
The website has been tested on the latest version of Google Chrome (34.0.1847.137 m) and Mozilla Firefox (29.0.1)