| Compound ID | 3301 |
| Compound Structure |  |
| Plant Source | Euphorbia peplis L. Common Name: |
| Source Family | Euphorbiaceae |
| Origin | India, Northern Italy |
| Plant Part Used | Leaf, stem |
| Extract | |
| Target Bacteria | Mycobacterium tuberculosis H172 |
| Assay / Test Done | |
| Positive Control Used (conc.) | Ciprofloxacin (0.25 µg/ml) |
| Inhibition [%] | |
| Activity [MIC] µg/ml | > 160 µg/ml |
| Activity (In terms of dilution) | |
| Activity (Zone of inhibition in mm) | |
| Active Compound Identified | 1 - O - (β - D - Glucopyranosyl) - (2S, 3S, 4E, 8E) - 2N - [(2R) - 2 - Hydroxyhexadecanoylamino] - 4 (E), 8 (E) - Octadecadiene - 1, 3 - Diol |
| PubChem ID | NR |
| Ethnomedicinal Information | |
| PubMed ID [Source Literature] | 14643323 |
| Extract Preparation | |
| Chemical Classification [Active Compound] | Aliphatic, Alkene, Cerebroside, Amide, Alcohol, Sugar |
| Media / Broth Used [Antimicrobial Assay/Test] | |
| Cytotoxicity Assay [AID] | |
| Molecular Weight | 713.544 |
| Molecular Formula | C40H75NO9 |
| SMILES | C(=O)(N[C@@H](CO[C@@H]1OC(C([C@H]([C@@H]1O)O)O)CO)[C@H](O)/C=C/CCC/C=C/CCCCCCCC)[C@H](O)CCCCCCCCCCCCCC |
| XLogP | 11.345 |
| PSA | 168.940 |
| H-bond Donor | 7 |
| H-bond Acceptor | 10 |
| No. of Rotatable Bond Count | 33 |
| No. of Rings | 1 |
| No. of N | 1 |
| No. of O | 9 |
| No. of S | 0 |
| Reference(s) | 1) Cateni F, Zilic J, Falsone G, Scialino G, Banfi E.New cerebrosides from Euphorbia peplis L.: antimicrobial activity evaluation.Bioorg Med Chem Lett. 2003 Dec 15;13(24):4345-50
|
| Curator | Vsheeba, vikramjitmandal |
