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                  Page - 1 of 1                  Record - 1 of 4   [TOP]
Compound ID3299
Compound Structure
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Plant SourceEuphorbia peplis L.     Common Name:
Source FamilyEuphorbiaceae
OriginIndia, Northern Italy
Plant Part UsedLeaf, stem
Extract
Target BacteriaMycobacterium tuberculosis H37Rv
Assay / Test Done
Positive Control Used (conc.)Ciprofloxacin (0.25 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml40 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified1 - O - (β - D - Glucopyranosyl) - (2S, 3S, 4R, 8Z) - 2N - [(2R) - 2 - Hydroxyhexacosenoil] - 8 (Z) - Octadecene - 1, 3, 4 - Triol
PubChem IDNR
Ethnomedicinal Information
PubMed ID [Source Literature]14643323
Extract Preparation
Chemical Classification [Active Compound]Aliphatic, Alkene, Cerebroside, Amide, Alcohol, Sugar
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]
Molecular Weight869.696
Molecular FormulaC50H95NO10
SMILESC(=O)(N[C@@H](CO[C@@H]1OC(C([C@H]([C@@H]1O)O)O)CO)[C@H](O)[C@@H](CCC/C=C/CCCCCCCCC)O)[C@H](O)CCCCCCCCCCCCCC/C=C/CCCCCCCC
XLogP15.528
PSA189.170
H-bond Donor8
H-bond Acceptor11
No. of Rotatable Bond Count43
No. of Rings1
No. of N1
No. of O10
No. of S0
Reference(s)1) Cateni F, Zilic J, Falsone G, Scialino G, Banfi E.New cerebrosides from Euphorbia peplis L.: antimicrobial activity evaluation.Bioorg Med Chem Lett. 2003 Dec 15;13(24):4345-50

CuratorVsheeba, vikramjitmandal

                  Record - 2 of 4   [TOP]
Compound ID3303
Compound Structure
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Plant SourceEuphorbia peplis L.     Common Name:
Source FamilyEuphorbiaceae
OriginIndia, Northern Italy
Plant Part UsedLeaf, stem
Extract
Target BacteriaMycobacterium tuberculosis H331
Assay / Test Done
Positive Control Used (conc.)Ciprofloxacin (0.125 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml40 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified1 - O - (β - D - Glucopyranosyl) - (2S, 3S, 4R, 8Z) - 2N - [(2R) - 2 - Hydroxyhexacosenoil] - 8 (Z) - Octadecene - 1, 3, 4 - Triol
PubChem IDNR
Ethnomedicinal Information
PubMed ID [Source Literature]14643323
Extract Preparation
Chemical Classification [Active Compound]Aliphatic, Alkene, Cerebroside, Amide, Alcohol, Sugar
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]
Molecular Weight869.696
Molecular FormulaC50H95NO10
SMILESC(=O)(N[C@@H](CO[C@@H]1OC(C([C@H]([C@@H]1O)O)O)CO)[C@H](O)[C@@H](CCC/C=C/CCCCCCCCC)O)[C@H](O)CCCCCCCCCCCCCC/C=C/CCCCCCCC
XLogP15.528
PSA189.170
H-bond Donor8
H-bond Acceptor11
No. of Rotatable Bond Count43
No. of Rings1
No. of N1
No. of O10
No. of S0
Reference(s)1) Cateni F, Zilic J, Falsone G, Scialino G, Banfi E.New cerebrosides from Euphorbia peplis L.: antimicrobial activity evaluation.Bioorg Med Chem Lett. 2003 Dec 15;13(24):4345-50

CuratorVsheeba, vikramjitmandal

                  Record - 3 of 4   [TOP]
Compound ID3304
Compound Structure
DOWNLOAD:
Plant SourceEuphorbia peplis L.     Common Name:
Source FamilyEuphorbiaceae
OriginIndia, Northern Italy
Plant Part UsedLeaf, stem
Extract
Target BacteriaMycobacterium tuberculosis H242
Assay / Test Done
Positive Control Used (conc.)Ciprofloxacin (0.125 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml80 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified1 - O - (β - D - Glucopyranosyl) - (2S, 3S, 4R, 8Z) - 2N - [(2R) - 2 - Hydroxyhexacosenoil] - 8 (Z) - Octadecene - 1, 3, 4 - Triol
PubChem IDNR
Ethnomedicinal Information
PubMed ID [Source Literature]14643323
Extract Preparation
Chemical Classification [Active Compound]Aliphatic, Alkene, Cerebroside, Amide, Alcohol, Sugar
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]
Molecular Weight869.696
Molecular FormulaC50H95NO10
SMILESC(=O)(N[C@@H](CO[C@@H]1OC(C([C@H]([C@@H]1O)O)O)CO)[C@H](O)[C@@H](CCC/C=C/CCCCCCCCC)O)[C@H](O)CCCCCCCCCCCCCC/C=C/CCCCCCCC
XLogP15.528
PSA189.170
H-bond Donor8
H-bond Acceptor11
No. of Rotatable Bond Count43
No. of Rings1
No. of N1
No. of O10
No. of S0
Reference(s)1) Cateni F, Zilic J, Falsone G, Scialino G, Banfi E.New cerebrosides from Euphorbia peplis L.: antimicrobial activity evaluation.Bioorg Med Chem Lett. 2003 Dec 15;13(24):4345-50

CuratorVsheeba, vikramjitmandal

                  Record - 4 of 4   [TOP]
Compound ID3305
Compound Structure
DOWNLOAD:
Plant SourceEuphorbia peplis L.     Common Name:
Source FamilyEuphorbiaceae
OriginIndia, Northern Italy
Plant Part UsedLeaf, stem
Extract
Target BacteriaMycobacterium tuberculosis H172
Assay / Test Done
Positive Control Used (conc.)Ciprofloxacin (0.25 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml40 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified1 - O - (β - D - Glucopyranosyl) - (2S, 3S, 4R, 8Z) - 2N - [(2R) - 2 - Hydroxyhexacosenoil] - 8 (Z) - Octadecene - 1, 3, 4 - Triol
PubChem IDNR
Ethnomedicinal Information
PubMed ID [Source Literature]14643323
Extract Preparation
Chemical Classification [Active Compound]Aliphatic, Alkene, Cerebroside, Amide, Alcohol, Sugar
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]
Molecular Weight869.696
Molecular FormulaC50H95NO10
SMILESC(=O)(N[C@@H](CO[C@@H]1OC(C([C@H]([C@@H]1O)O)O)CO)[C@H](O)[C@@H](CCC/C=C/CCCCCCCCC)O)[C@H](O)CCCCCCCCCCCCCC/C=C/CCCCCCCC
XLogP15.528
PSA189.170
H-bond Donor8
H-bond Acceptor11
No. of Rotatable Bond Count43
No. of Rings1
No. of N1
No. of O10
No. of S0
Reference(s)1) Cateni F, Zilic J, Falsone G, Scialino G, Banfi E.New cerebrosides from Euphorbia peplis L.: antimicrobial activity evaluation.Bioorg Med Chem Lett. 2003 Dec 15;13(24):4345-50

CuratorVsheeba, vikramjitmandal


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