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Compound ID3390
Compound Structure
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Plant SourceErythrina gibbosa     Common Name:NR
Source FamilyFabaceae
OriginPanamanian
Plant Part UsedNR
ExtractNR
Target BacteriaMycobacterium tuberculosis H37Rv
Assay / Test DoneAgar Dilution - Streak Assay
Positive Control Used (conc.)NR
Inhibition [%]NR
Activity [MIC] µg/ml>=25 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound IdentifiedErygibisoflavone
PubChem ID   392442
Ethnomedicinal InformationNR
PubMed ID [Source Literature]9828037
Extract PreparationNR
Chemical Classification [Active Compound]Aromatic, Tetracyclic, Flavonoid, Benzopyran, Phenol
Media / Broth Used [Antimicrobial Assay/Test]
Cytotoxicity Assay [AID]NR
Molecular Weight354.110
Molecular FormulaC20H18O6
SMILESO1C(C=Cc2c1c(C1COc3c(C1=O)c(O)cc(O)c3)ccc2O)(C)C
XLogP1.167
PSA96.220
H-bond Donor3
H-bond Acceptor6
No. of Rotatable Bond Count1
No. of Rings4
No. of N0
No. of O6
No. of S0
Reference(s)1) Mitscher LA, Baker W.Tuberculosis: a search for novel therapy starting with natural products.Med Res Rev. 1998 Nov;18(6):363-74

CuratorWvarsha, keyamukherjee, rachanake


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