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                  Page - 1 of 1                  Record - 1 of 2   [TOP]
Compound ID1818
Compound Structure
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Plant SourceGlycyrrhiza glabra L.     Common Name:Licorice, Liquorice (English), Yashtimadhu (Sanskrit)
Source FamilyFabaceae
OriginIndia, Africa
Plant Part UsedRoot
Extract
Target BacteriaMycobacterium tuberculosis
Assay / Test Done
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml25 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedLico - Isoflavone
PubChem ID   392443
Ethnomedicinal InformationExpectorant, consumption, bronchitis, chest complaint, cough
PubMed ID [Source Literature]17276637
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tetracyclic, Flavonoid, Benzopyran, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight354.110
Molecular FormulaC20H18O6
SMILESO1C(C=Cc2c(O)c(C3COc4c(C3=O)c(O)cc(O)c4)ccc12)(C)C
XLogP1.167
PSA96.220
H-bond Donor3
H-bond Acceptor6
No. of Rotatable Bond Count1
No. of Rings4
No. of N0
No. of O6
No. of S0
Reference(s)1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34

Curator

                  Record - 2 of 2   [TOP]
Compound ID1819
Compound Structure
DOWNLOAD:
Plant SourceGlycyrrhiza glabra L.     Common Name:Licorice, Liquorice (English), Yashtimadhu (Sanskrit)
Source FamilyFabaceae
OriginIndia, Africa
Plant Part UsedRoot
Extract
Target BacteriaMycobacterium smegmatis
Assay / Test Done
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedLico - Isoflavone
PubChem ID   392443
Ethnomedicinal InformationExpectorant, consumption, bronchitis, chest complaint, cough
PubMed ID [Source Literature]17276637
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tetracyclic, Flavonoid, Benzopyran, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight354.110
Molecular FormulaC20H18O6
SMILESO1C(C=Cc2c(O)c(C3COc4c(C3=O)c(O)cc(O)c4)ccc12)(C)C
XLogP1.167
PSA96.220
H-bond Donor3
H-bond Acceptor6
No. of Rotatable Bond Count1
No. of Rings4
No. of N0
No. of O6
No. of S0
Reference(s)1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34

Curator


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