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Compound ID1932
Compound Structure
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Plant SourceIpomoea leptophylla     Common Name:Bush Morning Glory, Manroot
Source FamilyConvolvulaceae
OriginNorth America
Plant Part UsedLeaf
ExtractSoluble extract
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneBACTEC 460 radiometric system
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/mlNR
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedTrans - Cinnamic Acid
PubChem ID   444539
Ethnomedicinal InformationTreatment for stomach troubles, tuberculosis
PubMed ID [Source Literature]14640518
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Alkene, Acid
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight148.052
Molecular FormulaC9H8O2
SMILESOC(=O)/C=C/c1ccccc1
XLogP3.904
PSA37.300
H-bond Donor1
H-bond Acceptor2
No. of Rotatable Bond Count2
No. of Rings1
No. of N0
No. of O2
No. of S0
Reference(s)1) Barnes CC, Smalley MK, Manfredi KP, Kindscher K, Loring H, Sheeley DM.Characterization of an anti-tuberculosis resin glycoside from the prairie medicinal plant Ipomoea leptophylla.J Nat Prod. 2003 Nov;66(11):1457-62

Curator


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