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                  Page - 1 of 1                  Record - 1 of 4   [TOP]
Compound ID3936
Compound Structure
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Plant SourceAllium stipitatum Regel     Common Name:Ornamental Onion, Glory of Pamir
Source FamilyAmaryllidaceae
OriginSpalding, Lincolnshire, UK
Plant Part UsedBulb
ExtractNR
Target BacteriaMycobacterium fortuitum
Assay / Test DoneNR
Positive Control Used (conc.)Ethambutol (2 µg/ml), Isoniazid (128 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml> 128 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound Identified2 - (Methyldithio) Thiophene
PubChem ID   45272211
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19093848
Extract PreparationNR
Chemical Classification [Active Compound]Aromatic, Thiophene, Disulfide
Media / Broth Used [Antimicrobial Assay/Test]Columbia blood agar (Oxoid)
Cytotoxicity Assay [AID]Sulforhodamine B Short - Term Cytotoxicity Assay
Molecular Weight161.963
Molecular FormulaC5H6S3
SMILESS1c(SSC)ccc1
XLogP2.741
PSA78.840
H-bond Donor0
H-bond Acceptor3
No. of Rotatable Bond Count2
No. of Rings1
No. of N0
No. of O0
No. of S3
Reference(s)1) O'Donnell G, Poeschl R, Zimhony O, Gunaratnam M, Moreira JB, Neidle S, Evangelopoulos D, Bhakta S, Malkinson JP, Boshoff HI, Lenaerts A, Gibbons S.Bioactive pyridine-N-oxide disulfides from Allium stipitatum.J Nat Prod. 2009 Mar 27;72(3):360-5

CuratorVikramjitmandal

                  Record - 2 of 4   [TOP]
Compound ID3937
Compound Structure
DOWNLOAD:
Plant SourceAllium stipitatum Regel     Common Name:Ornamental Onion, Glory of Pamir
Source FamilyAmaryllidaceae
OriginSpalding, Lincolnshire, UK
Plant Part UsedBulb
ExtractNR
Target BacteriaMycobacterium smegmatis
Assay / Test DoneNR
Positive Control Used (conc.)Ethambutol (2 µg/ml), Isoniazid (128 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml64 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound Identified2 - (Methyldithio) Thiophene
PubChem ID   45272211
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19093848
Extract PreparationNR
Chemical Classification [Active Compound]Aromatic, Thiophene, Disulfide
Media / Broth Used [Antimicrobial Assay/Test]Columbia blood agar (Oxoid)
Cytotoxicity Assay [AID]Sulforhodamine B Short - Term Cytotoxicity Assay
Molecular Weight161.963
Molecular FormulaC5H6S3
SMILESS1c(SSC)ccc1
XLogP2.741
PSA78.840
H-bond Donor0
H-bond Acceptor3
No. of Rotatable Bond Count2
No. of Rings1
No. of N0
No. of O0
No. of S3
Reference(s)1) O'Donnell G, Poeschl R, Zimhony O, Gunaratnam M, Moreira JB, Neidle S, Evangelopoulos D, Bhakta S, Malkinson JP, Boshoff HI, Lenaerts A, Gibbons S.Bioactive pyridine-N-oxide disulfides from Allium stipitatum.J Nat Prod. 2009 Mar 27;72(3):360-5

CuratorVikramjitmandal

                  Record - 3 of 4   [TOP]
Compound ID3938
Compound Structure
DOWNLOAD:
Plant SourceAllium stipitatum Regel     Common Name:Ornamental Onion, Glory of Pamir
Source FamilyAmaryllidaceae
OriginSpalding, Lincolnshire, UK
Plant Part UsedBulb
ExtractNR
Target BacteriaMycobacterium smegmatis (mc2 2700)
Assay / Test DoneNR
Positive Control Used (conc.)Ethambutol (2 µg/ml), Isoniazid (128 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/mlNot tested
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound Identified2 - (Methyldithio) Thiophene
PubChem ID   45272211
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19093848
Extract PreparationNR
Chemical Classification [Active Compound]Aromatic, Thiophene, Disulfide
Media / Broth Used [Antimicrobial Assay/Test]Columbia blood agar (Oxoid)
Cytotoxicity Assay [AID]Sulforhodamine B Short - Term Cytotoxicity Assay
Molecular Weight161.963
Molecular FormulaC5H6S3
SMILESS1c(SSC)ccc1
XLogP2.741
PSA78.840
H-bond Donor0
H-bond Acceptor3
No. of Rotatable Bond Count2
No. of Rings1
No. of N0
No. of O0
No. of S3
Reference(s)1) O'Donnell G, Poeschl R, Zimhony O, Gunaratnam M, Moreira JB, Neidle S, Evangelopoulos D, Bhakta S, Malkinson JP, Boshoff HI, Lenaerts A, Gibbons S.Bioactive pyridine-N-oxide disulfides from Allium stipitatum.J Nat Prod. 2009 Mar 27;72(3):360-5

CuratorVikramjitmandal

                  Record - 4 of 4   [TOP]
Compound ID3939
Compound Structure
DOWNLOAD:
Plant SourceAllium stipitatum Regel     Common Name:Ornamental Onion, Glory of Pamir
Source FamilyAmaryllidaceae
OriginSpalding, Lincolnshire, UK
Plant Part UsedBulb
ExtractNR
Target BacteriaMycobacterium phlei
Assay / Test DoneNR
Positive Control Used (conc.)Ethambutol (2 µg/ml), Isoniazid (128 µg/ml)
Inhibition [%]NR
Activity [MIC] µg/ml> 128 µg/ml
Activity (In terms of dilution)NR
Activity (Zone of inhibition in mm)NR
Active Compound Identified2 - (Methyldithio) Thiophene
PubChem ID   45272211
Ethnomedicinal InformationNR
PubMed ID [Source Literature]19093848
Extract PreparationNR
Chemical Classification [Active Compound]Aromatic, Thiophene, Disulfide
Media / Broth Used [Antimicrobial Assay/Test]Columbia blood agar (Oxoid)
Cytotoxicity Assay [AID]Sulforhodamine B Short - Term Cytotoxicity Assay
Molecular Weight161.963
Molecular FormulaC5H6S3
SMILESS1c(SSC)ccc1
XLogP2.741
PSA78.840
H-bond Donor0
H-bond Acceptor3
No. of Rotatable Bond Count2
No. of Rings1
No. of N0
No. of O0
No. of S3
Reference(s)1) O'Donnell G, Poeschl R, Zimhony O, Gunaratnam M, Moreira JB, Neidle S, Evangelopoulos D, Bhakta S, Malkinson JP, Boshoff HI, Lenaerts A, Gibbons S.Bioactive pyridine-N-oxide disulfides from Allium stipitatum.J Nat Prod. 2009 Mar 27;72(3):360-5

CuratorVikramjitmandal


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