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Compound ID1971
Compound Structure
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Plant SourceKaempferia parviflora     Common Name:Krachai Dhum
Source FamilyZingiberaceae
OriginAsia
Plant Part Used
Extract
Target BacteriaMycobacterium tuberculosis
Assay / Test DoneMicroplate Alamar Blue Assay (MABA)
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml200 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified3, 5, 7, 4' - Tetramethoxyflavone
PubChem ID   631095
Ethnomedicinal InformationAnti-mycobacterial
PubMed ID [Source Literature]14693228
Extract PreparationN/A
Chemical Classification [Active Compound]Aromatic, Tricyclic, Flavonoid, Ether
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]Against KB (oral human epidermoid carcinoma), BC (breast cancer), and NCI-H187 (human, small cell lung cancer) cell lines
Molecular Weight342.110
Molecular FormulaC19H18O6
SMILESO1c2c(c(=O)c(OC)c1c1ccc(OC)cc1)c(OC)cc(OC)c2
XLogP3.059
PSA53.990
H-bond Donor0
H-bond Acceptor5
No. of Rotatable Bond Count5
No. of Rings3
No. of N0
No. of O6
No. of S0
Reference(s)1) Yenjai C, Prasanphen K, Daodee S, Wongpanich V, Kittakoop P.Bioactive flavonoids from Kaempferia parviflora.Fitoterapia. 2004 Jan;75(1):89-92

Curator


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