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Compound ID1429
Compound Structure
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Plant SourceChamaedora tepejilote     Common Name:Pacaya Palm
Source FamilyArecaceae (Palmae)
OriginMexico
Plant Part UsedLeaf
ExtractHexane
Target BacteriaMycobacterium tuberculosis H37Rv
Assay / Test DoneRadiorespirometric BACTEC Assay
Positive Control Used (conc.)
Inhibition [%]99 %
Activity [MIC] µg/ml100 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedSqualene
PubChem ID   638072
Ethnomedicinal InformationCough, Pneumonia
PubMed ID [Source Literature]16041726
Extract PreparationN/A
Chemical Classification [Active Compound]Aliphatic, Alkene, Terpene, Triterpene
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight410.391
Molecular FormulaC30H50
SMILESC(C/C=C(/CCC=C(C)C)C)/C(=C/CC/C=C(/CC/C=C(/CCC=C(C)C)C)C)/C
XLogP11.482
PSA0.000
H-bond Donor0
H-bond Acceptor0
No. of Rotatable Bond Count15
No. of Rings0
No. of N0
No. of O0
No. of S0
Reference(s)1) Jiménez A, Meckes M, Alvarez V, Torres J, Parra R. Secondary metabolites from Chamaedora tepejilote (Palmae) are active against Mycobacterium tuberculosis.Phytother Res. 2005 Apr;19(4):320-2

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