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                  Page - 1 of 1                  Record - 1 of 3   [TOP]
Compound ID2531
Compound Structure
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Plant SourceSalvia Africana-lutea     Common Name:Beach Salvia, Dune Salvia
Source FamilyLamiaceae
OriginAfrica
Plant Part Used
Extract
Target BacteriaMycobacterium aurum
Assay / Test Done
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml2000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedCarnosic acid
PubChem ID   65126
Ethnomedicinal InformationInfections, tuberculosis, fever
PubMed ID [Source Literature]17256988
Extract PreparationN/A
Chemical Classification [Active Compound]Alicyclic, Tricyclic, Terpene, Diterpene, Acetoxy, Acid, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight332.199
Molecular FormulaC20H28O4
SMILESOC(=O)[C@@]12[C@H](C(CCC1)(C)C)CCc1c2c(O)c(O)c(c1)C(C)C
XLogP5.183
PSA77.760
H-bond Donor3
H-bond Acceptor4
No. of Rotatable Bond Count2
No. of Rings3
No. of N0
No. of O4
No. of S0
Reference(s)1) Hussein AA, Meyer JJ, Jimeno ML, Reodríguez B.Bioactive diterpenes from Orthosiphon labiatus and Salvia africana-luta.J Nat Prod. 2007 Feb;70(2):293-5

2) Seaman, T., 2005. The antimicrobial and antimycobacterial activity of plants used for the treatment of respiratory ailments in Southern Africa and the isolation of anacardic acid from Ozoroa paniculosa. M.Sc. Dissertation. University of the Witwatersrand, South Africa

Curator

                  Record - 2 of 3   [TOP]
Compound ID2532
Compound Structure
DOWNLOAD:
Plant SourceSalvia Africana-lutea     Common Name:Beach Salvia, Dune Salvia
Source FamilyLamiaceae
OriginAfrica
Plant Part Used
Extract
Target BacteriaMycobacterium tuberculosis
Assay / Test Done
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml9 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedCarnosic acid
PubChem ID   65126
Ethnomedicinal InformationInfections, tuberculosis, fever
PubMed ID [Source Literature]17256988
Extract PreparationN/A
Chemical Classification [Active Compound]Alicyclic, Tricyclic, Terpene, Diterpene, Acetoxy, Acid, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight332.199
Molecular FormulaC20H28O4
SMILESOC(=O)[C@@]12[C@H](C(CCC1)(C)C)CCc1c2c(O)c(O)c(c1)C(C)C
XLogP5.183
PSA77.760
H-bond Donor3
H-bond Acceptor4
No. of Rotatable Bond Count2
No. of Rings3
No. of N0
No. of O4
No. of S0
Reference(s)1) Hussein AA, Meyer JJ, Jimeno ML, Rodríguez B.Bioactive diterpenes from Orthosiphon labiatus and Salvia africana-lutea.J Nat Prod. 2007 Feb;70(2):293-5

Curator

                  Record - 3 of 3   [TOP]
Compound ID2533
Compound Structure
DOWNLOAD:
Plant SourceSalvia Africana-lutea     Common Name:Beach Salvia, Dune Salvia
Source FamilyLamiaceae
OriginAfrica
Plant Part Used
Extract
Target BacteriaMycobacterium smegmatis
Assay / Test Done
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml8000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound IdentifiedCarnosic acid
PubChem ID   65126
Ethnomedicinal InformationInfections, tuberculosis, fever
PubMed ID [Source Literature]17256988
Extract PreparationN/A
Chemical Classification [Active Compound]Alicyclic, Tricyclic, Terpene, Diterpene, Acetoxy, Acid, Phenol
Media / Broth Used [Antimicrobial Assay/Test]N/A
Cytotoxicity Assay [AID]N/A
Molecular Weight332.199
Molecular FormulaC20H28O4
SMILESOC(=O)[C@@]12[C@H](C(CCC1)(C)C)CCc1c2c(O)c(O)c(c1)C(C)C
XLogP5.183
PSA77.760
H-bond Donor3
H-bond Acceptor4
No. of Rotatable Bond Count2
No. of Rings3
No. of N0
No. of O4
No. of S0
Reference(s)1) Hussein AA, Meyer JJ, Jimeno ML, Rodríguez B.Bioactive diterpenes from Orthosiphon labiatus and Salvia africana-lutea.J Nat Prod. 2007 Feb;70(2):293-5

2) Seaman, T., 2005. The antimicrobial and antimycobacterial activity of plants used for the treatment of respiratory ailments in Southern Africa and the isolation of anacardic acid from Ozoroa paniculosa. M.Sc. Dissertation. University of the Witwatersrand, South Africa

Curator


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