BioPhytMol: A database of Phytomolecules against Mycobacteria

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Page - 1 of 3 Record - 1 of 70 [TOP]

Compound ID	1009
Compound Structure
Plant Source	Acacia kempeana F.Muell. Common Name:Witchetty Bush
Source Family	Mimosaceae
Origin	Australia
Plant Part Used	Bark, root bark, leaf
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum, Mycobacterium smegmatis
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Chest infection, severe colds, general sickness
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 2 of 70 [TOP]

Compound ID	1023
Compound Structure
Plant Source	Acacia tetragonophylla F. Muell. Common Name:Dead Finish, Kurara
Source Family	Mimosaceae
Origin	Australia
Plant Part Used	Leaf, stem
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum, Mycobacterium smegmatis
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Cough, treatment of circumcision wounds, dysentery
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 3 of 70 [TOP]

Compound ID	1029
Compound Structure
Plant Source	Acalypha indica L. Common Name:Indian Acalypha (English), Arittamanjarie (Sanskrit)
Source Family	Euphorbiaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium fortuitum (TMC 1529)
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	0 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Respiratory disorder
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13 2) Indian Medicinal Plants: An Illustrated Dictionary By C.P. Khare
Curator

Record - 4 of 70 [TOP]

Compound ID	1055
Compound Structure	N/A
Plant Source	Adhatoda vasica Nees Common Name:Malabar Nut Tree (English), Vasaka (Sanskrit)
Source Family	Acanthaceae
Origin	India
Plant Part Used	Leaf
Extract	Water
Target Bacteria	Mycobacterium fortuitum (TMC 1529)
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	0 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified	N/A
PubChem ID	NR
Ethnomedicinal Information	Treatment of tuberculosis, asthma and also as expectorants, bronchial disorders such as acute and chronic cough, bronchitis
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
Curator

Record - 5 of 70 [TOP]

Compound ID	1097
Compound Structure
Plant Source	Allium cepa L. Common Name:Onion (English), Palaandu, Durgandh (Sanskrit)
Source Family	Amaryllidaceae
Origin	Malaysia, India
Plant Part Used	Bulb
Extract	Water
Target Bacteria	Mycobacterium fortuitum (TMC 1529)
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	0 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cough
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
Curator

Record - 6 of 70 [TOP]

Compound ID

1106

Compound Structure

Plant Source

Allium sativum L. Common Name:Garlic (English), Lashuna (Sanskrit)

Source Family

Amaryllidaceae

Origin

India, Africa, Malaysia

Plant Part Used

Bulb

Extract

Water

Target Bacteria

Mycobacterium fortuitum

Assay / Test Done

Agar - Dilution Test

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

3350 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Allicin

PubChem ID

65036

Ethnomedicinal Information

Bronchitis, asthma, expectorant, cough, pulmonary phthisis, consumption, chronic diseases of lungs, whooping cough, laryngeal tuberculosis

PubMed ID [Source Literature]

4004189

Extract Preparation

N/A

Chemical Classification [Active Compound]

Aliphatic, Alkene, Disulfide

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

162.017

Molecular Formula

C₆H₁₀OS₂

SMILES

S(=O)(SCC=C)CC=C

XLogP

0.237

PSA

61.580

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Delaha EC, Garagusi VF.Inhibition of mycobacteria by garlic extract (Allium sativum).Antimicrob Agents Chemother. 1985 Apr;27(4):485-6

Curator

Record - 7 of 70 [TOP]

Compound ID	1128
Compound Structure
Plant Source	Allium sativum L. Common Name:Garlic (English), Lashuna (Sanskrit)
Source Family	Amaryllidaceae
Origin	India, Africa, Malaysia
Plant Part Used	Clove
Extract	Water
Target Bacteria	Mycobacterium fortuitum (TMC 1529)
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	0 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Bronchitis, asthma, expectorant, cough, pulmonary phthisis, consumption, chronic diseases of lungs, whooping cough, laryngeal tuberculosis
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
Curator

Record - 8 of 70 [TOP]

Compound ID	1150
Compound Structure
Plant Source	Aloe vera L. Common Name:Aloe vera (English)
Source Family	Xanthorrhoeaceae
Origin	India, Malaysia
Plant Part Used	Leaf
Extract	Pure gel
Target Bacteria	Mycobacterium fortuitum (TMC 1529)
Assay / Test Done	Middlebrook 7H9 Broth using BacT/ALERT 3D System
Positive Control Used (conc.)	Isoniazid, Rifampin
Inhibition [%]	0 %
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Asthma and cough
PubMed ID [Source Literature]	20571171
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gupta R, Thakur B, Singh P, Singh HB, Sharma VD, Katoch VM, Chauhan SV.Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.Indian J Med Res. 2010 Jun;131:809-13
Curator

Record - 9 of 70 [TOP]

Compound ID	1171
Compound Structure
Plant Source	Amyema quandang (Lindley) Tieghem var. quandang Common Name:Grey Mistletoe
Source Family	Loranthaceae
Origin	Australia
Plant Part Used	Leaf
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum, Mycobacterium smegmatis
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Fever
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 10 of 70 [TOP]

Compound ID	1376
Compound Structure
Plant Source	Carissa edulis Vahl Common Name:Carrisse, Carandas Plum
Source Family	Apocynaceae
Origin	Kenya
Plant Part Used	Root
Extract	Methanol
Target Bacteria	Mycobacterium fortuitum
Assay / Test Done	BACTEC MGIT™ 960 System
Positive Control Used (conc.)	Isoniazid (2, 1 and 0.5 mg/ml)
Inhibition [%]	100 %
Activity [MIC] µg/ml	0.5, 1 and 2 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Polio, tuberculosis, asthma, gonorrhea, malaria
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
Curator

Record - 11 of 70 [TOP]

Compound ID	1490
Compound Structure
Plant Source	Clerodendrum myricoides (Hochst)Vatke Common Name:Butterfly Bush, Blue Glory Bower
Source Family	Verbenaceae
Origin	Kenya
Plant Part Used	Root
Extract	Methanol
Target Bacteria	Mycobacterium fortuitum
Assay / Test Done	BACTEC MGIT™ 960 System
Positive Control Used (conc.)	Isoniazid (2, 1 and 0.5 mg/ml)
Inhibition [%]	100 %
Activity [MIC] µg/ml	1, 2 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Gonorrhea, mumps, tuberculosis, chest problems, hepatitis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791
Curator

Record - 12 of 70 [TOP]

Compound ID	1507
Compound Structure
Plant Source	Codonocarpus cotinifolius (Desf.) F. Muell. Common Name:Bell Fruit Tree, Desert Poplar, Horseradish Tree, Mustard Tree, Native Poplar
Source Family	Gyrostemonaceae
Origin	Australia
Plant Part Used	Leaf, stem
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum, Mycobacterium smegmatis
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Skin sores, chest pain, respiratory infection
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 13 of 70 [TOP]

Compound ID

1514

Compound Structure

Plant Source

Combretum imberbe Wawra Common Name:Leadwood

Source Family

Combretaceae

Origin

Africa

Plant Part Used

Leaf

Extract

Target Bacteria

Mycobacterium fortuitum

Assay / Test Done

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

1.56 µg/ml

Activity (In terms of dilution)

Activity (Zone of inhibition in mm)

Active Compound Identified

Imberbic acid

PubChem ID

Ethnomedicinal Information

Combretum species used for chest coughs, fever, infections

PubMed ID [Source Literature]

12657301

Extract Preparation

N/A

Chemical Classification [Active Compound]

Alicyclic, Pentacyclic, Triterpene, Hydroxy, Acid

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

472.355

Molecular Formula

C₃₀H₄₈O₄

SMILES

C1([C@H]2[C@@]([C@@H]3[C@@](CC2)([C@]2(C(=CC3)[C@H]3[C@@](CC2)(CC[C@](C3)(C(=O)O)C)C)C)C)([C@H](C[C@@H]1O)O)C)(C)C

XLogP

7.389

PSA

77.760

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Katerere DR, Gray AI, Nash RJ, Waigh RD.Antimicrobial activity of pentacyclic triterpenes isolated from African Combretaceae.Phytochemistry. 2003 May;63(1):81-8

Curator

Record - 14 of 70 [TOP]

Compound ID	1559
Compound Structure
Plant Source	Croton macrostachyus Hochst. ex Ferret et Galinier Common Name:Broad - Leaved Croton
Source Family	Euphorbiaceae
Origin	Kenya
Plant Part Used	Stem bark
Extract	Methanol
Target Bacteria	Mycobacterium fortuitum
Assay / Test Done	BACTEC MGIT™ 960 System
Positive Control Used (conc.)	Isoniazid (2, 1 and 0.5 mg/ml)
Inhibition [%]	100 %
Activity [MIC] µg/ml	2000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Stomach ache, tuberculosis, asthma, coughs, rheumatism
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791 2) http://www.fao.org/docrep/x5327e/x5327e07.htm
Curator

Record - 15 of 70 [TOP]

Compound ID	1582
Compound Structure
Plant Source	Cymbopogon ambiguus (Steudel) A.Camus Common Name:Scent Grass, Lemon Grass
Source Family	Poaceae
Origin	Australia
Plant Part Used	Leaf
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum, Mycobacterium smegmatis
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Respiratory tract infection, headache, fever, skin complaints, eye wash
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 16 of 70 [TOP]

Compound ID	1584
Compound Structure
Plant Source	Cymbopogon obtectus S.T.Blake Common Name:Silky Heads
Source Family	Poaceae
Origin	Australia
Plant Part Used	Aerial
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum, Mycobacterium smegmatis
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Respiratory tract infection
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 17 of 70 [TOP]

Compound ID	1634
Compound Structure
Plant Source	Eremophila alternifolia R. Br. Common Name:Poverty Bush
Source Family	Myoporaceae
Origin	Australia
Plant Part Used	Leaf, stem
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	66000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	General sickness, pain, respiratory track infection
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 18 of 70 [TOP]

Compound ID	1636
Compound Structure
Plant Source	Eremophila duttonii F.Muell. Common Name:Budda or Harlequin Fuchsia Bush
Source Family	Myoporaceae
Origin	Australia
Plant Part Used	Leaf, stem
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum, Mycobacterium smegmatis
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Respiratory tract infection, sore throat, skin cuts, painful ears, inflamed eyes
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 19 of 70 [TOP]

Compound ID	1637
Compound Structure
Plant Source	Eremophila latrobei F. Muell. Subsp. Glabra(L.S. Smith)Chinn. Common Name:Crimson Turkey Bush
Source Family	Myoporaceae
Origin	Australia
Plant Part Used	Leaf, stem
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum, Mycobacterium smegmatis
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Malaise, cough, respiratory track infection, sore throat
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 20 of 70 [TOP]

Compound ID	1638
Compound Structure
Plant Source	Eremophila longifolia (R.Br.) F.Muell. Common Name:Berrigan
Source Family	Myoporaceae
Origin	Australia
Plant Part Used	Stem
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	40000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Skin sores and boils, respiratory track infection, eye wash
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 21 of 70 [TOP]

Compound ID	1640
Compound Structure
Plant Source	Eremophila sturtii R.Br. Common Name:Narrow Leaf Emu Bush, Turpentine Bush
Source Family	Myoporaceae
Origin	Australia
Plant Part Used	Leaf, stem
Extract	Ethanol
Target Bacteria	Mycobacterium fortuitum, Mycobacterium smegmatis
Assay / Test Done	Plate - Hole Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cough, general sickness, skin cuts, sore eyes, respiratory infection
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Michelle Meilak and Enzo A. Palombo.Anti-Mycobacterial Activity of Extracts Derived from Australian Medicinal Plants.Research Journal of Microbiology 3 (7): 535-538, 2008
Curator

Record - 22 of 70 [TOP]

Compound ID	1649
Compound Structure
Plant Source	Erythrina abyssinica Lam ex DC Common Name:Lucky - Bean Tree, Red - Hot - Poker Tree (English), Munhimbiti, Mutsiti (Sanskrit)
Source Family	Fabaceae
Origin	Kenya
Plant Part Used	Bark, root
Extract	Methanol
Target Bacteria	Mycobacterium fortuitum
Assay / Test Done	BACTEC MGIT™ 960 System
Positive Control Used (conc.)	Isoniazid (2, 1 and 0.5 mg/ml)
Inhibition [%]	100 %
Activity [MIC] µg/ml	2 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis, malaria, stomach ache
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Mariita, Richard M.; Okemo, Paul O.; Orodho, John A.; Kirimuhuzya, Claude; Otieno, Joseph N.; Magadula, J. Joseph.Efficacy of 13 medicinal plants used by indigenous communities around Lake Victoria, Kenya, against tuberculosis, diarrhoea aausing bacteria and candida albicans.Pharmacy & Technology IJPT, Sep-2010, Vol. 2, Issue No.3, 771-791 2) http://www.zimbabweflora.co.zw/speciesdata/species.php?species_id=131450
Curator

Record - 23 of 70 [TOP]

Compound ID	1673
Compound Structure
Plant Source	Euclea natalensis A. DC. Common Name:Natal Guarri, Natal Ebony, Large Leaved Guarri
Source Family	Ebenaceae
Origin	Africa
Plant Part Used	Root
Extract	Acetone
Target Bacteria	Mycobacterium fortuitum
Assay / Test Done	Modified two - fold serial dilution assay
Positive Control Used (conc.)	Isoniazid (1.95 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	58.5 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Respiratory chest problems, coughs, tuberculosis
PubMed ID [Source Literature]	18591787
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) McGaw LJ, Lall N, Hlokwe TM, Michel AL, Meyer JJ, Eloff JN.Purified compounds and extracts from Euclea species with antimycobacterial activity against Mycobacterium bovis and fast-growing mycobacteria.Biol Pharm Bull. 2008 Jul;31(7):1429-33
Curator

Record - 24 of 70 [TOP]

Compound ID	1674
Compound Structure
Plant Source	Euclea natalensis A. DC. Common Name:Natal Guarri, Natal Ebony, Large Leaved Guarri
Source Family	Ebenaceae
Origin	Africa
Plant Part Used	Root
Extract	Chloroform
Target Bacteria	Mycobacterium fortuitum
Assay / Test Done	Modified two - fold serial dilution assay
Positive Control Used (conc.)	Isoniazid (1.95 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	65.81 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Respiratory chest problems, coughs, tuberculosis
PubMed ID [Source Literature]	18591787
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) McGaw LJ, Lall N, Hlokwe TM, Michel AL, Meyer JJ, Eloff JN.Purified compounds and extracts from Euclea species with antimycobacterial activity against Mycobacterium bovis and fast-growing mycobacteria.Biol Pharm Bull. 2008 Jul;31(7):1429-33
Curator

Record - 25 of 70 [TOP]

Compound ID	1675
Compound Structure
Plant Source	Euclea natalensis A. DC. Common Name:Natal Guarri, Natal Ebony, Large Leaved Guarri
Source Family	Ebenaceae
Origin	Africa
Plant Part Used	Root
Extract	Methanol
Target Bacteria	Mycobacterium fortuitum
Assay / Test Done	Modified two - fold serial dilution assay
Positive Control Used (conc.)	Isoniazid (1.95 µg/ml)
Inhibition [%]
Activity [MIC] µg/ml	469 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Respiratory chest problems, coughs, tuberculosis
PubMed ID [Source Literature]	18591787
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) McGaw LJ, Lall N, Hlokwe TM, Michel AL, Meyer JJ, Eloff JN.Purified compounds and extracts from Euclea species with antimycobacterial activity against Mycobacterium bovis and fast-growing mycobacteria.Biol Pharm Bull. 2008 Jul;31(7):1429-33
Curator

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