BioPhytMol: A database of Phytomolecules against Mycobacteria

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Page - 1 of 6 Record - 1 of 126 [TOP]

Compound ID	1081
Compound Structure
Plant Source	Agrimonia eupatoria L. Common Name:Agrimony, Stickle Wort (English)
Source Family	Rosaceae
Origin	India
Plant Part Used	Whole plant
Extract	Chloroform
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Agar - Dilution Test
Positive Control Used (conc.)	Gentamicin (0.01 g/ml)
Inhibition [%]
Activity [MIC] µg/ml	100000 µg of dried plant/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	General infectious diseases, antiseptic, disinfectant, cough
PubMed ID [Source Literature]	3325696
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Ríos JL, Recio MC, Villar A.Antimicrobial activity of selected plants employed in the Spanish Mediterranean area.J Ethnopharmacol. 1987 Nov;21(2):139-52
Curator

Record - 2 of 126 [TOP]

Compound ID	1183
Compound Structure
Plant Source	Angelica archangelica L Common Name:Chandaa, Chandaamshuka, Kathachoraa (Sanskrit)
Source Family	Apiaceae (Umbelliferae)
Origin	India
Plant Part Used	Seed
Extract	Ethanol (95 %)
Target Bacteria	Mycobacterium smegmatis, Mycobacterium phlei
Assay / Test Done	Agar - Well Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	50 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	13 - 18 mm
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Bronchial cold, expectorant
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 3 of 126 [TOP]

Compound ID	1245
Compound Structure
Plant Source	Bauhinia vahlii Wt. & Arn. Common Name:
Source Family	Caesalpiniaceae
Origin	India
Plant Part Used	Root
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	3000000 µg/ml of dried plant material
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Dysentery, stomach ache, tonic, aphrodisiac, cuts, wounds
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 4 of 126 [TOP]

Compound ID	1249
Compound Structure
Plant Source	Berberis vulgaris L. Common Name:Common Barberry, True Barberry (English), Daruharidraa (Sanskrit)
Source Family	Berberidaceae
Origin	India
Plant Part Used	Whole plant
Extract	Chloroform
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Agar - Dilution Test
Positive Control Used (conc.)	Gentamicin (0.01 mg/ml)
Inhibition [%]
Activity [MIC] µg/ml	100000 µg dried plant/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	General infectious diseases, antiseptic, disinfectant
PubMed ID [Source Literature]	3325696
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Ríos JL, Recio MC, Villar A.Antimicrobial activity of selected plants employed in the Spanish Mediterranean area.J Ethnopharmacol. 1987 Nov;21(2):139-52
Curator

Record - 5 of 126 [TOP]

Compound ID	1250
Compound Structure
Plant Source	Berberis vulgaris L. Common Name:Common Barberry, True Barberry (English), Daruharidraa (Sanskrit)
Source Family	Berberidaceae
Origin	India
Plant Part Used
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Agar - Dilution Test
Positive Control Used (conc.)	Gentamicin (0.01 mg/ml)
Inhibition [%]
Activity [MIC] µg/ml	10400 µg dried plant/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	General infectious diseases, antiseptic, disinfectant
PubMed ID [Source Literature]	3325696
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Ríos JL, Recio MC, Villar A.Antimicrobial activity of selected plants employed in the Spanish Mediterranean area.J Ethnopharmacol. 1987 Nov;21(2):139-52
Curator

Record - 6 of 126 [TOP]

Compound ID	1310
Compound Structure
Plant Source	Buxus papillosa C. K. syn. Buxus sempervirens L. Common Name:Himalayan Boxwood Tree (English)
Source Family	Buxaceae
Origin	India
Plant Part Used	Whole plant
Extract	Ethanol (95 %)
Target Bacteria	Mycobacterium smegmatis, Mycobacterium phlei
Assay / Test Done	Agar - Well Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	13 - 18 mm at 50 µl of extract
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Combs, pain, headache, stomatitis, febrifuge, syphilis, rheumatism, diaphoretic, random screening
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 14. Lalit Mohan Basu, Allahabad, India
Curator

Record - 7 of 126 [TOP]

Compound ID	1368
Compound Structure
Plant Source	Capsella bursa-pastoris (L.) Moench Common Name:Shepherd's Purse (English)
Source Family	Brassicaceae
Origin	India
Plant Part Used	Whole plant
Extract	Chloroform
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Agar - Dilution Test
Positive Control Used (conc.)	Gentamicin (0.01 mg/ml)
Inhibition [%]
Activity [MIC] µg/ml	77000 µg dried plant/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	General infectious diseases, antiseptic, disinfectant
PubMed ID [Source Literature]	3325696
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Ríos JL, Recio MC, Villar A.Antimicrobial activity of selected plants employed in the Spanish Mediterranean area.J Ethnopharmacol. 1987 Nov;21(2):139-52
Curator

Record - 8 of 126 [TOP]

Compound ID	1454
Compound Structure
Plant Source	Cirsium arvense (L.) Scop. Common Name:Creeping Thistle, Canada Thistle (English)
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Whole plant
Extract	Ethanol (95 %)
Target Bacteria	Mycobacterium phlei, Mycobacterium smegmatis
Assay / Test Done
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Emetic, diuretic, tonic, diaphoretic, emmenagogue
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Frisbey A, Roberts J, Jennings J, Gottshall R, Lucas E (1953) The occurrence of antibacterial substances in seed plants with special reference to Mycobacterium tuberculosis (Third Report). Michigan State College of Agriculture and Applied Science Quarterly Bulletin 35: 392-404 2) Anonymous, 1986. The Useful Plants of India. Council of Scientific and Industrial Research, New Delhi, India
Curator

Record - 9 of 126 [TOP]

Compound ID	1532
Compound Structure
Plant Source	Conyza aegyptiaca (L.) Ait. Common Name:
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Leaf
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	2 mg/Disc
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Skin diseases
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 10 of 126 [TOP]

Compound ID

1533

Compound Structure

Plant Source

Coptis coinensia French Common Name:

Source Family

Ranunculaceae

Origin

China

Plant Part Used

Root

Extract

Target Bacteria

Mycobacterium phlei

Assay / Test Done

Positive Control Used (conc.)

Inhibition [%]

Activity [MIC] µg/ml

Activity (In terms of dilution)

1:800 dilution

Activity (Zone of inhibition in mm)

Active Compound Identified

Berberine bisulphate

PubChem ID

12457

Ethnomedicinal Information

Tuberculosis

PubMed ID [Source Literature]

14778141

Extract Preparation

N/A

Chemical Classification [Active Compound]

Aromatic, Tetracyclic, Isoquinoline, Sulphate

Media / Broth Used [Antimicrobial Assay/Test]

N/A

Cytotoxicity Assay [AID]

N/A

Molecular Weight

336.124

Molecular Formula

C₂₀H₁₉NO₈S

SMILES

S(=O)(=O)(O)[O-].O1c2cc3CC[n+]4c(c3cc2OC1)cc1c(c4)c(OC)c(OC)cc1

XLogP

2.896

PSA

40.800

H-bond Donor

H-bond Acceptor

No. of Rotatable Bond Count

No. of Rings

No. of N

No. of O

No. of S

Reference(s)

1) Wang VF.In vitro antibacterial activity of some common Chinese herbs on Mycobacteria tuberculosis.Chin Med J. 1950 May-Jun;68(5-6):169-72

Curator

Record - 11 of 126 [TOP]

Compound ID	1541
Compound Structure
Plant Source	Corydalis rutaefolia Sibth. syn. Corydalis longipes D.Don · Prodr. Common Name:
Source Family	Papaveraceae
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml of dried plant material
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Typhoid fever
PubMed ID [Source Literature]	17276637
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Gautam R, Saklani A, Jachak SM.Indian medicinal plants as a source of antimycobacterial agents.J Ethnopharmacol. 2007 Mar 21;110(2):200-34
Curator

Record - 12 of 126 [TOP]

Compound ID	1570
Compound Structure
Plant Source	Cucurbita pepo L. Common Name:Pumpkin, Marrow (English)
Source Family	Cucurbitaceae
Origin	India
Plant Part Used	Fruit
Extract	Ethanol (95 %)
Target Bacteria	Mycobacterium phlei
Assay / Test Done
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, bronchitis
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Frisbey, A., Roberts, J.M., Jennings, J.C., Gottshall, R.Y., Lucas, E.H., 1953. The occurrence of antibacterial substances in seed plants with special reference to Mycobacterium tuberculosis. Michigan State University Agricultural Applied Science Quaternary Bulletin 35, 392–404 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India
Curator

Record - 13 of 126 [TOP]

Compound ID	1603
Compound Structure
Plant Source	Didymocarpus subalternans Wall. syn. Didymocarpus primulifolia Don Prodr. Common Name:
Source Family	Gesneriaceae
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml of dried plant
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Flu
PubMed ID [Source Literature]	7564413
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Manandhar NP, Towers GH.Screening of selected medicinal plants of Nepal for antimicrobial activities.J Ethnopharmacol. 1995 Jun;46(3):153-9
Curator

Record - 14 of 126 [TOP]

Compound ID	1618
Compound Structure
Plant Source	Drymaria cordata Willd. Common Name:Whitesnow (English)
Source Family	Caryophyllaceae
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml of dried plant
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Asthma, cough, cold
PubMed ID [Source Literature]	7564413
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Manandhar NP, Towers GH.Screening of selected medicinal plants of Nepal for antimicrobial activities.J Ethnopharmacol. 1995 Jun;46(3):153-9
Curator

Record - 15 of 126 [TOP]

Compound ID	1625
Compound Structure
Plant Source	Elephantopus scaber L. Common Name:Mayura Shikhaa, Gojihvaa (Sanskrit)
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml of dried plant
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Bronchitis, cough, cold
PubMed ID [Source Literature]	7564413
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Manandhar NP, Towers GH.Screening of selected medicinal plants of Nepal for antimicrobial activities.J Ethnopharmacol. 1995 Jun;46(3):153-9 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit Mohan Basu, Allahabad, India
Curator

Record - 16 of 126 [TOP]

Compound ID	1626
Compound Structure
Plant Source	Elsholtzia blanda Benth. Common Name:
Source Family	Lamiaceae
Origin	India
Plant Part Used	Aerial
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml of dried plant material
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Cough and cold
PubMed ID [Source Literature]	7564413
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Manandhar NP, Towers GH.Screening of selected medicinal plants of Nepal for antimicrobial activities.J Ethnopharmacol. 1995 Jun;46(3):153-9
Curator

Record - 17 of 126 [TOP]

Compound ID	1712
Compound Structure
Plant Source	Eupatorium odoratum L. Common Name:Thoroughwort (English)
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Aerial
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol
Inhibition [%]
Activity [MIC] µg/ml	300000 µg/ml of dried plant material
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, dysentery, gastric complaints, pain, to stop bleeding, cuts, wounds
PubMed ID [Source Literature]	8866730
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Edel F, Manandhar NP, Towers GH.Antimicrobial activities of southern Nepalese medicinal plants.J Ethnopharmacol. 1996 Feb;50(2):97-102
Curator

Record - 18 of 126 [TOP]

Compound ID	1774
Compound Structure
Plant Source	Fragaria vesca L. var. brateata(Heller) Davis Common Name:Woodland Strawberry (English)
Source Family	Rosaceae
Origin	India, British Columbia
Plant Part Used	Leaf
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Gentamicin (10 µg/Disc)
Inhibition [%]
Activity [MIC] µg/ml	20000 µg/ml of dried plant material
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	10.1 - 15.0 mm, > 25 mm (control)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Astringent, diuretic, arthritis, gout, liver tonic, boosts your skin internally, digestive upsets, diarrhea, mild laxative action, improving digestion
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) A.R. McCutcheon, R.W. Stokes, L.M. Thorson, S.M. Ellis, R.E.W. Hancock and G.H.N. Towers.Anti-Mycobacterial Screening of British Columbian Medicinal Plants.Pharmaceutical Biology, 1997, Vol. 35, No. 2 , Pages 77-83
Curator

Record - 19 of 126 [TOP]

Compound ID	1780
Compound Structure
Plant Source	Fumaria officinalis L. Common Name:Fumaria officinalis L (English), Parpata (Sanskrit)
Source Family	Papaveraceae
Origin	India
Plant Part Used	Aerial
Extract	Chloroform
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Agar - Dilution Test
Positive Control Used (conc.)	Gentamicin (0.01 mg/ml)
Inhibition [%]
Activity [MIC] µg/ml	500 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Leprosy, wound healing, antiseptic and disinfectant qualities, laxative, tonic, blood diseases
PubMed ID [Source Literature]	3325696
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Ríos JL, Recio MC, Villar A.Antimicrobial activity of selected plants employed in the Spanish Mediterranean area.J Ethnopharmacol. 1987 Nov;21(2):139-52 2) Anonymous, 1986. The Useful Plants of India. Council of Scientific and Industrial Research, New Delhi, India
Curator

Record - 20 of 126 [TOP]

Compound ID	1886
Compound Structure
Plant Source	Hypericum cordifolium Choisy Common Name:
Source Family	Hypericaceae
Origin	India
Plant Part Used	Aerial
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol (2 g/ml)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	The allied species H. perforatum L. for chronic catarrh of lungs and H. japonicum Thunb. for asthma, used in ethnomedicine for other diseases
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Manandhar NP, Towers GH.Screening of selected medicinal plants of Nepal for antimicrobial activities.J Ethnopharmacol. 1995 Jun;46(3):153-9 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit
Curator

Record - 21 of 126 [TOP]

Compound ID	1887
Compound Structure
Plant Source	Hypericum elodeoides Choisy Common Name:
Source Family	Hypericaceae
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Chloramphenicol (2 g/ml)
Inhibition [%]
Activity [MIC] µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Fever
PubMed ID [Source Literature]
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Taylor RS, Manandhar NP, Towers GH.Screening of selected medicinal plants of Nepal for antimicrobial activities.J Ethnopharmacol. 1995 Jun;46(3):153-9 2) Kirtikar, K.R., Basu, B.D., 1935. Indian Medicinal Plants, vols. 1–4. Lalit
Curator

Record - 22 of 126 [TOP]

Compound ID	1889
Compound Structure
Plant Source	Hypericum perforatum L. Common Name:Common St. John's Wort (English)
Source Family	Hypericaceae
Origin	India, British Columbia
Plant Part Used	Aerial
Extract	Chloroform
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Agar - Dilution Test
Positive Control Used (conc.)	Gentamicin (0.01 mg/ml)
Inhibition [%]
Activity [MIC] µg/ml	> 1000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Wound healing, antiseptic and disinfectant qualities,cough, expectorant, chronic catarrh of lungs
PubMed ID [Source Literature]	3325696
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Ríos JL, Recio MC, Villar A.Antimicrobial activity of selected plants employed in the Spanish Mediterranean area.J Ethnopharmacol. 1987 Nov;21(2):139-52
Curator

Record - 23 of 126 [TOP]

Compound ID	1890
Compound Structure
Plant Source	Hypericum perforatum L. Common Name:Common St. John's wort (English)
Source Family	Hypericaceae
Origin	India, British Columbia
Plant Part Used	Aerial
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Disk Diffusion Assay
Positive Control Used (conc.)	Gentamicin (10 µg/Disc)
Inhibition [%]
Activity [MIC] µg/ml	2000000 µg/ml
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)	15.1 mm, 20.0 mm, > 25mm (control)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Wound healing, antiseptic and disinfectant qualities,cough, expectorant, chronic catarrh of lungs
PubMed ID [Source Literature]	1453710
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) McCutcheon AR, Ellis SM, Hancock RE, Towers GH.Antibiotic screening of medicinal plants of the British Columbian native peoples.J Ethnopharmacol. 1992 Oct;37(3):213-23
Curator

Record - 24 of 126 [TOP]

Compound ID	1926
Compound Structure
Plant Source	Inula racemosa Hook. f. syn. Inula helenium L. Common Name:Elecampane (English), Pushkaramula, Pushkara, Paushkara, Padmapatra, Kaashmira, Kushtha - bheda (Sanskrit)
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Whole plant
Extract	Chloroform
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Agar - Dilution Test
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	8900 µg/ml of dried plant
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis, lung disorders, cough, expectorant, random screening, bronchitis
PubMed ID [Source Literature]	3325696
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Ríos JL, Recio MC, Villar A.Antimicrobial activity of selected plants employed in the Spanish Mediterranean area.J Ethnopharmacol. 1987 Nov;21(2):139-52
Curator

Record - 25 of 126 [TOP]

Compound ID	1927
Compound Structure
Plant Source	Inula racemosa Hook. f. syn. Inula helenium L. Common Name:Elecampane (English), Pushkaramula, Pushkara, Paushkara, Padmapatra, Kaashmira, Kushtha - bheda (Sanskrit)
Source Family	Asteraceae (Compositae)
Origin	India
Plant Part Used	Whole plant
Extract	Methanol
Target Bacteria	Mycobacterium phlei
Assay / Test Done	Agar - Dilution Test
Positive Control Used (conc.)
Inhibition [%]
Activity [MIC] µg/ml	11800 µg/ml of dried plant
Activity (In terms of dilution)
Activity (Zone of inhibition in mm)
Active Compound Identified
PubChem ID	NR
Ethnomedicinal Information	Tuberculosis, lung disorders, cough, expectorant, random screening, bronchitis
PubMed ID [Source Literature]	3325696
Extract Preparation	N/A
Chemical Classification [Active Compound]	N/A
Media / Broth Used [Antimicrobial Assay/Test]	N/A
Cytotoxicity Assay [AID]	N/A
Reference(s)	1) Ríos JL, Recio MC, Villar A.Antimicrobial activity of selected plants employed in the Spanish Mediterranean area.J Ethnopharmacol. 1987 Nov;21(2):139-52
Curator

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