• siRNAmod is a manually curated database of experimentally validated chemically modified siRNAs.
  • Currently the database provides experimental information of 4894 chemically modified siRNAs (excluding 435 siRNA sequences as control) and their respective biological activity.
  • 128 unique chemical modifications with detailed information about number and positions of each chemical modification in both sense and antisense are provided.
  • We have reported chemical modifications individually and in different permutations and combinations used in both sense and antisense strands.
  • Chemical information about modifications is incorporated including SMILES, InChel, structure.
  • This database is hoped to be useful for researchers working on siRNA-based therapeutics.
  • Thank you for visting our web site. If you use this resource please site us as:
    Dar, S. A. et al. siRNAmod: A database of experimentally validated chemically modified siRNAs. Sci. Rep. 6, 20031; doi: 10.1038/srep20031 (2016) PMID: 26818131.