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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
- By modification in sense strand
- By modification position in sense strand
- By modification in antisense strand
- By modification position in antisense strand
- Reference
Total number of Results for 1,3,5,9,12,14,17,20,21 are 2
Results from 0 - 25
SMDBid | siRNA (sense/antisense) 5'>3' | Modification (sense/antisense) | Position (sense/antisense) |
Modified component (sense/antisense) |
Efficacy (%) | Reference |
SM3063 |
TGAGAGAAAGCACAGAAAATT UUUUCUGUGCUUUCUCUCATT |
Locked nucleic acid 0 |
1,3,5,9,12,14,17,20,21 0 |
Sugar 0 |
68 percent target mRNA inhibition | 15653644 |
SM4743 |
TGAGAGAAAGCACAGAAAATT UGAGAGAAAGCACAGAAAATT |
Locked nucleic acid 2-Deoxy |
1,3,5,9,12,14,17,20,21 20,21 |
Sugar Sugar |
64 percent target mRNA inhibition | US 8653252 B2 |