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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
- By modification in sense strand
- By modification position in sense strand
- By modification in antisense strand
- By modification position in antisense strand
- Reference
Total number of Results for 1,4,8,9,11,14,15,18 are 2
Results from 0 - 25
SMDBid | siRNA (sense/antisense) 5'>3' | Modification (sense/antisense) | Position (sense/antisense) |
Modified component (sense/antisense) |
Efficacy (%) | Reference |
SM2487 |
CAGCAAACCACGAUCAAUATT UAUUGAUCGUGGUUUGCUGTT |
2-O-Methyl 2-O-Methyl |
1,4,8,9,11,14,15,18 1,3,4,7,8,10,13,14,15,17,18 |
Sugar Sugar |
5 percent target mRNA inhibition | 22889374 |
SM2488 |
CAGCAAACCACGAUCAAUATT UAUUGAUCGUGGUUUGCUGTT |
2-Fluoro 2-Fluoro |
1,4,8,9,11,14,15,18 1,3,4,7,8,10,13,14,15,17,18 |
Sugar Sugar |
71 percent target mRNA inhibition | 22889374 |