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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 12834349 are 20
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM3343
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    Locked nucleic acid
    Locked nucleic acid
    21
    1
    Sugar
    Sugar
    NA
    12834349
    SM3344
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    Locked nucleic acid
    Locked nucleic acid
    1
    21
    Sugar
    Sugar
    NA
    12834349
    SM3345
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    Locked nucleic acid
    Locked nucleic acid
    1,8,13,21
    1,7,18,21
    Sugar
    Sugar
    NA
    12834349
    SM3346
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    Locked nucleic acid
    Locked nucleic acid
    1,21
    1,21
    Sugar
    Sugar
    NA
    12834349
    SM3347
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    Locked nucleic acid
    Locked nucleic acid
    8,13
    7,18
    Sugar
    Sugar
    NA
    12834349
    SM3348
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    Locked nucleic acid
    Locked nucleic acid
    4,13
    4,18
    Sugar
    Sugar
    NA
    12834349
    SM3349
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    Locked nucleic acid
    Locked nucleic acid
    5,6,17,18
    4,6,16,18
    Sugar
    Sugar
    NA
    12834349
    SM3351
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    Phosphorothioate
    Phosphorothioate
    1,2,20,21
    1,2,20,21
    Phosphate
    Phosphate
    NA
    12834349
    SM3352
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    Phosphorothioate
    Phosphorothioate
    1,2,3,4,18,19,20,21
    1,2,3,4,18,19,20,21
    Phosphate
    Phosphate
    NA
    12834349
    SM3353
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    Phosphorothioate
    Phosphorothioate
    1,2,3,4,5,6,15,16,17,18,19,20,21
    1,2,3,4,5,6,15,16,17,18,19,20,21
    Phosphate
    Phosphate
    NA
    12834349
    SM3354
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    Phosphorothioate
    Phosphorothioate
    1,2,3,4,5,6,7,8,14,15,16,17,18,19,20,21
    1,2,3,4,5,6,7,8,14,15,16,17,18,19,20,21
    Phosphate
    Phosphate
    NA
    12834349
    SM3355
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    Phosphorothioate
    Phosphorothioate
    1,2,3,4,5,6,7,8,9,10,11,12,13,14,14,15,16,17,18,19,20,21
    1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21
    Phosphate
    Phosphate
    NA
    12834349
    SM3356
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    0
    2-Deoxy-2-fluorouridine
    0
    1
    0
    Sugar
    NA
    12834349
    SM3357
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    0
    2-Deoxy-2-fluorouridine
    0
    20
    0
    Sugar
    NA
    12834349
    SM3358
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    0
    2-Deoxy-2-fluorouridine
    0
    3,20
    0
    Sugar
    NA
    12834349
    SM3359
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    2-Deoxy-2-fluorouridine
    0
    21
    0
    Sugar
    0
    NA
    12834349
    SM3360
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    2-Deoxy-2-fluorouridine
    0
    9
    0
    Sugar
    0
    NA
    12834349
    SM3361
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    2-Deoxy-2-fluorouridine
    0
    9,21
    0
    Sugar
    0
    NA
    12834349
    SM3362
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    2-Deoxy-2-fluorouridine
    2-Deoxy-2-fluorouridine
    21
    1
    Sugar
    Sugar
    NA
    12834349
    SM3363
    AGACGAGCUGAGCGAGAAGTT
    TTUCUGCUCGACUCGCUCUUC
    2-Deoxy-2-fluorouridine
    2-Deoxy-2-fluorouridine
    9,21
    3,20
    Sugar
    Sugar
    NA
    12834349