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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 18575806 are 10
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2192
    GCAGCACGACUUCUUCAAGUU
    CUUGAAGAAGUCGUGCUGCUU
    0
    2-O-Methyl
    0
    2
    0
    Sugar
    71.74 percent target mRNA inhibition
    18575806
    SM2193
    GCAGCACGACUUCUUCAAGUU
    CUUGAAGAAGUCGUGCUGCUU
    0
    2-Fluoro
    0
    2
    0
    Sugar
    73.84 percent target mRNA inhibition
    18575806
    SM2194
    GCAGCACGACUUCUUCAAGUU
    CUUGAAGAAGUCGUGCUGCUU
    Locked nucleic acid
    0
    1
    0
    Sugar
    0
    73.23 percent target mRNA inhibition
    18575806
    SM2195
    GCAGCACGACUUCUUCAAGUU
    CUUGAAGAAGUCGUGCUGCUU
    Locked nucleic acid
    2-O-Methyl
    1
    2
    Sugar
    Sugar
    68.59 percent target mRNA inhibition
    18575806
    SM2196
    GCAGCACGACUUCUUCAAGUU
    CUUGAAGAAGUCGUGCUGCUU
    Locked nucleic acid
    2-Fluoro
    1
    2
    Sugar
    Sugar
    69.33 percent target mRNA inhibition
    18575806
    SM2197
    GCAGCACGACUUCUUCAAGUU
    CUUGAAGAAGUCGUGCUGCUU
    2-O-Methyl
    0
    2
    0
    Sugar
    0
    71.74 percent target mRNA inhibition
    18575806
    SM2198
    GCAGCACGACUUCUUCAAGUU
    CUUGAAGAAGUCGUGCUGCUU
    2-O-Methyl
    2-O-Methyl
    2
    2
    Sugar
    Sugar
    62.72 percent target mRNA inhibition
    18575806
    SM2199
    GCAGCACGACUUCUUCAAGUU
    UUCGUCGUGCUGAAGAAGUUC
    2-O-Methyl
    2-Fluoro
    2
    2
    Sugar
    Sugar
    77.23 percent target mRNA inhibition
    18575806
    SM2201
    UAGUUCUGUGGGGCUGUUUUU
    AAACAGCCCCACAGAACUAUU
    Locked nucleic acid
    2-Fluoro
    1
    2
    Sugar
    Sugar
    NA
    18575806
    SM2202
    UAGUUCUGUGGGGCUGUUUUU
    AAACAGCCCCACAGAACUAUU
    2-O-Methyl
    2-Fluoro
    2
    2
    Sugar
    Sugar
    NA
    18575806