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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
- By modification in sense strand
- By modification position in sense strand
- By modification in antisense strand
- By modification position in antisense strand
- Reference
Total number of Results for 2,15,20 are 3
Results from 0 - 25
SMDBid | siRNA (sense/antisense) 5'>3' | Modification (sense/antisense) | Position (sense/antisense) |
Modified component (sense/antisense) |
Efficacy (%) | Reference |
SM4557 |
CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT |
Triazole-linked nucleic acid 2-Deoxythymidine |
2,15,20 20,21 |
Backbone Sugar |
49 percent target mRNA inhibition | 22260772 |
SM4572 |
CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT |
Triazole-linked nucleic acid 2-Deoxythymidine |
2,15,20 20,21 |
Backbone Sugar |
74 percent target mRNA inhibition | 22260772 |
SM4587 |
CUUACGCUGAGUACUUCGATT UCGAAGUACUCAGCGUAAGTT |
Triazole-linked nucleic acid 2-Deoxythymidine |
2,15,20 20,21 |
Backbone Sugar |
77 percent target mRNA inhibition | 22260772 |