Browse By

Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
  • Total number of Results for 21739319 are 10
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2941
    AAGCUGACCCUGAAGUUCAUCUGCACC
    GGUGCAGAUGAACUUCAGGGUCAGCUU
    Phosphorothioate
    Phosphorothioate
    2,27
    2,27
    Phosphate
    Phosphate
    95 percent target mRNA inhibition
    21739319
    SM2942
    AAGCUGACCCUGAAGUUCAUCUGCACC
    GGUGCAGAUGAACUUCAGGGUCAGCUU
    Phosphorothioate
    Phosphorothioate
    2,3,4,25,26,27
    2,3,4,25,26,27
    Phosphate
    Phosphate
    93 percent target mRNA inhibition
    21739319
    SM2943
    AAGCUGACCCUGAAGUUCAUCUGCACC
    GGUGCAGAUGAACUUCAGGGUCAGCUU
    Dimethoxy-Nitrophenyl Ethyl group
    Dimethoxy-Nitrophenyl Ethyl group
    1,27
    1,27
    Phosphate
    Phosphate
    43 percent target mRNA inhibition
    21739319
    SM2944
    AAGCUGACCCUGAAGUUCAUCUGCACC
    GGUGCAGAUGAACUUCAGGGUCAGCUU
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    2,27 * 1,27
    2,27 * 1,27
    Phosphate
    Phosphate
    27 percent target mRNA inhibition
    21739319
    SM2945
    AAGCUGACCCUGAAGUUCAUCUGCACC
    GGUGCAGAUGAACUUCAGGGUCAGCUU
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    2,3,4,25,26,27 * 1,27
    2,3,4,25,26,27 * 1,27
    Phosphate
    Phosphate
    40 percent target mRNA inhibition
    21739319
    SM2947
    AAGCUGACCCUGAAGUUCAUCUGCACC
    GGUGCAGAUGAACUUCAGGGUCAGCUU
    Phosphorothioate
    Phosphorothioate
    2,27
    2,27
    Phosphate
    Phosphate
    93 percent target mRNA inhibition
    21739319
    SM2948
    AAGCUGACCCUGAAGUUCAUCUGCACC
    GGUGCAGAUGAACUUCAGGGUCAGCUU
    Phosphorothioate
    Phosphorothioate
    2,3,4,25,26,27
    2,3,4,25,26,27
    Phosphate
    Phosphate
    93 percent target mRNA inhibition
    21739319
    SM2949
    AAGCUGACCCUGAAGUUCAUCUGCACC
    GGUGCAGAUGAACUUCAGGGUCAGCUU
    Dimethoxy-Nitrophenyl Ethyl group
    Dimethoxy-Nitrophenyl Ethyl group
    1,27
    1,27
    Phosphate
    Phosphate
    13 percent target mRNA inhibition
    21739319
    SM2950
    AAGCUGACCCUGAAGUUCAUCUGCACC
    GGUGCAGAUGAACUUCAGGGUCAGCUU
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    2,27 * 1,27
    2,27 * 1,27
    Phosphate
    Phosphate
    89 percent target mRNA inhibition
    21739319
    SM2951
    AAGCUGACCCUGAAGUUCAUCUGCACC
    GGUGCAGAUGAACUUCAGGGUCAGCUU
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    Phosphorothioate* Dimethoxy-Nitrophenyl Ethyl group
    2,3,4,25,26,27 * 1,27
    2,3,4,25,26,27 * 1,27
    Phosphate
    Phosphate
    88 percent target mRNA inhibition
    21739319