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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
  • By modification in sense strand

  • By modification position in sense strand

  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for 23344622 are 10
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2455
    CAAGUGUCAUCACACUGAAUU
    UUCAGUGUGAUGACACUUGUU
    2-O-Methyl* Inverted abasic
    2-O-Methyl
    20,21 * 1,21
    20,21
    Sugar; Base
    Sugar
    91 percent target mRNA inhibition
    23344622
    SM2456
    CAAGUGUCAUCACACUGAAUU
    UUCAGUGUGAUGACACUUGUU
    2-O-Methyl* Inverted abasic
    2-O-Methyl* 2-O-Benzyl
    20,21 * 1,21
    20,21 * 5
    Sugar; Base
    Sugar
    94 percent target mRNA inhibition
    23344622
    SM2457
    CAAGUGUCAUCACACUGAAUU
    UUCAGUGUGAUGACACUUGUU
    2-O-Methyl* Inverted abasic
    2-O-Methyl* 2-O-Benzyl
    20,21 * 1,21
    20,21 * 8
    Sugar; Base
    Sugar
    96 percent target mRNA inhibition
    23344622
    SM2458
    CAAGUGUCAUCACACUGAAUU
    UUCAGUGUGAUGACACUUGUU
    2-O-Methyl* Inverted abasic
    2-O-Methyl* 2-O-Benzyl
    20,21 * 1,21
    20,21 * 15
    Sugar; Base
    Sugar
    97 percent target mRNA inhibition
    23344622
    SM2459
    CAAGUGUCAUCACACUGAAUU
    UUCAGUGUGAUGACACUUGUU
    2-O-Methyl* Inverted abasic
    2-O-Methyl* 2-O-Benzyl
    20,21 * 1,21
    20,21 * 19
    Sugar; Base
    Sugar
    92 percent target mRNA inhibition
    23344622
    SM2460
    CAAGUGUCAUCACACUGAAUU
    UUCAGUGUGAUGACACUUGUU
    2-O-Methyl* Inverted abasic
    2-O-Methyl
    20,21 * 1,21
    20,21
    Sugar; Base
    Sugar
    64 percent target mRNA inhibition
    23344622
    SM2461
    CAAGUGUCAUCACACUGAAUU
    UUCAGUGUGAUGACACUUGUU
    2-O-Methyl* Inverted abasic
    2-O-Methyl* 2-O-Benzyl
    20,21 * 1,21
    20,21 * 5
    Sugar; Base
    Sugar
    78 percent target mRNA inhibition
    23344622
    SM2462
    CAAGUGUCAUCACACUGAAUU
    UUCAGUGUGAUGACACUUGUU
    2-O-Methyl* Inverted abasic
    2-O-Methyl* 2-O-Benzyl
    20,21 * 1,21
    20,21 * 8
    Sugar; Base
    Sugar
    87 percent target mRNA inhibition
    23344622
    SM2463
    CAAGUGUCAUCACA CUGAAUU
    UUCAGUGUGAUGACACUUGUU
    2-O-Methyl* Inverted abasic
    2-O-Methyl* 2-O-Benzyl
    20,21 * 1,21
    20,21 * 15
    Sugar; Base
    Sugar
    87 percent target mRNA inhibition
    23344622
    SM2464
    CAAGUGUCAUCACA CUGAAUU
    UUCAGUGUGAUGACACUUGUU
    2-O-Methyl* Inverted abasic
    2-O-Methyl* 2-O-Benzyl
    20,21 * 1,21
    20,21 * 19
    Sugar; Base
    Sugar
    72 percent target mRNA inhibition
    23344622