Browse By

Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 3,9,13,15,20,21 are 105
Results from 0 - 25

« previous12345next »

SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM0026	GACGUAAACG + GCCACAAGUTC ACUUGUGGCCGUUUACGUCGC	Locked nucleic acid 2-O-Methyl	3,9,13,15,20,21 2	Sugar Sugar	73 percent target mRNA inhibition	19282453
SM0032	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGC	Locked nucleic acid 2-O-Methyl	3,9,13,15,20,21 2	Sugar Sugar	16 percent target mRNA inhibition	19282453
SM0072	GACGUAAACG + GCCACAAGUTC ACUUGUGGCCGUUUACGUCGCU	Locked nucleic acid 2-O-Methyl* 2-Aminoethyl	3,9,13,15,20,21 1 * 21	Sugar Sugar	60 percent target mRNA inhibition	19282453
SM0078	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGCU	Locked nucleic acid 2-O-Methyl* 2-Aminoethyl	3,9,13,15,20,21 1 * 21	Sugar Sugar	75 percent target mRNA inhibition	19282453
SM0117	GACGUAAACG + GCCACAAGUTC ACUUGUGGCCGUUUACGUCGCU	Locked nucleic acid 2-O-Methyl* 2-Cyanoethyl	3,9,13,15,20,21 1 * 18	Sugar Sugar	18.3 percent target mRNA inhibition	19282453
SM0123	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGCU	Locked nucleic acid 2-O-Methyl* 2-Cyanoethyl	3,9,13,15,20,21 1 * 18	Sugar Sugar	0 percent target mRNA inhibition	19282453
SM0162	GACGUAAACG + GCCACAAGUTC ACUUGUGGCCGUUUACGUCGC	Locked nucleic acid Altritol nucleic acid	3,9,13,15,20,21 1,2	Sugar Sugar	50.1 percent target mRNA inhibition	19282453
SM0168	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGC	Locked nucleic acid Altritol nucleic acid	3,9,13,15,20,21 1,2	Sugar Sugar	3 percent target mRNA inhibition	19282453
SM0207	GACGUAAACG + GCCACAAGUTC ACUUGUGGCCGUUUACGUCGCU	Locked nucleic acid Altritol nucleic acid	3,9,13,15,20,21 20,21	Sugar Sugar	87.9 percent target mRNA inhibition	19282453
SM0213	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGCU	Locked nucleic acid Altritol nucleic acid	3,9,13,15,20,21 20,21	Sugar Sugar	87.7 percent target mRNA inhibition	19282453
SM0252	GACGUAAACG + GCCACAAGUTC ACUUGUGGCCGUUUACGUCGCU	Locked nucleic acid Altritol nucleic acid	3,9,13,15,20,21 5,8,11,14,17,20	Sugar Sugar	29.1 percent target mRNA inhibition	19282453
SM0258	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGCU	Locked nucleic acid Altritol nucleic acid	3,9,13,15,20,21 5,8,11,14,17,20	Sugar Sugar	0 percent target mRNA inhibition	19282453
SM0297	GACGUAAACG + GCCACAAGUTC ACUUGUGGCCGUUUACGUCGCU	Locked nucleic acid Altritol nucleic acid	3,9,13,15,20,21 3,6,14,18,20,21	Sugar Sugar	76.7 percent target mRNA inhibition	19282453
SM0303	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGCU	Locked nucleic acid Altritol nucleic acid	3,9,13,15,20,21 3,6,14,18,20,21	Sugar Sugar	12.8 percent target mRNA inhibition	19282453
SM0342	GACGUAAACG + GCCACAAGUTC ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,13,15,20,21 18,19,20 * 21	Sugar Sugar	83.2 percent target mRNA inhibition	19282453
SM0348	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,13,15,20,21 18,19,20 * 21	Sugar Sugar	72.2 percent target mRNA inhibition	19282453
SM0387	GACGUAAACG + GCCACAAGUTC ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,13,15,20,21 2,18,19,20 * 21	Sugar Sugar	70.3 percent target mRNA inhibition	19282453
SM0388	GACGUAAACG + GCCACAAGUTC ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,13,15,20,21 2,18,19,20 * 21	Sugar Sugar	70.3 percent target mRNA inhibition	19282453
SM0393	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,13,15,20,21 2,18,19,20 * 21	Sugar Sugar	58.7 percent target mRNA inhibition	19282453
SM0432	GACGUAAACG + GCCACAAGUTC ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,13,15,20,21 3,18,19,20 * 21	Sugar Sugar	75.4 percent target mRNA inhibition	19282453
SM0438	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,13,15,20,21 3,18,19,20 * 21	Sugar Sugar	50.4 percent target mRNA inhibition	19282453
SM0477	GACGUAAACG + GCCACAAGUTC ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,13,15,20,21 2,9,18,19,20 * 21	Sugar Sugar	21.1 percent target mRNA inhibition	19282453
SM0483	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,13,15,20,21 2,9,18,19,20 * 21	Sugar Sugar	0 percent target mRNA inhibition	19282453
SM0522	GACGUAAACG + GCCACAAGUTC ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid 2-Aminoethoxymethyl* 2-Deoxy	3,9,13,15,20,21 18,19 * 21	Sugar Sugar	35.1 percent target mRNA inhibition	19282453
SM0528	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid 2-Aminoethoxymethyl* 2-Deoxy	3,9,13,15,20,21 18,19 * 21	Sugar Sugar	0 percent target mRNA inhibition	19282453



« previous12345next »