Browse By

Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).

• By modification in sense strand


• By modification position in sense strand


• By modification in antisense strand


• By modification position in antisense strand


• Reference
Total number of Results for 3,9,15,20,21 are 96
Results from 0 - 25

« previous1234next »

SMDBid	siRNA (sense/antisense) 5'>3'	Modification (sense/antisense)	Position (sense/antisense)	Modified component (sense/antisense)	Efficacy (%)	Reference
SM0023	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGC	Locked nucleic acid 2-O-Methyl	3,9,15,20,21 2	Sugar Sugar	31 percent target mRNA inhibition	19282453
SM0036	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGC	Alfa-L-Locked nucleic acid 2-O-Methyl	3,9,15,20,21 2	Sugar Sugar	71 percent target mRNA inhibition	19282453
SM0069	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGCU	Locked nucleic acid 2-O-Methyl* 2-Aminoethyl	3,9,15,20,21 1 * 21	Sugar Sugar	72 percent target mRNA inhibition	19282453
SM0082	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGCU	Alfa-L-Locked nucleic acid 2-O-Methyl* 2-Aminoethyl	3,9,15,20,21 1 * 21	Sugar Sugar	85.4 percent target mRNA inhibition	19282453
SM0114	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGCU	Locked nucleic acid 2-O-Methyl* 2-Cyanoethyl	3,9,15,20,21 1 * 18	Sugar Sugar	32.9 percent target mRNA inhibition	19282453
SM0127	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGCU	Alfa-L-Locked nucleic acid 2-O-Methyl* 2-Cyanoethyl	3,9,15,20,21 1 * 18	Sugar Sugar	58.9 percent target mRNA inhibition	19282453
SM0159	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGC	Locked nucleic acid Altritol nucleic acid	3,9,15,20,21 1,2	Sugar Sugar	8.4 percent target mRNA inhibition	19282453
SM0172	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGC	Alfa-L-Locked nucleic acid Altritol nucleic acid	3,9,15,20,21 1,2	Sugar Sugar	54.4 percent target mRNA inhibition	19282453
SM0204	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGCU	Locked nucleic acid Altritol nucleic acid	3,9,15,20,21 20,21	Sugar Sugar	89.3 percent target mRNA inhibition	19282453
SM0217	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGCU	Alfa-L-Locked nucleic acid Altritol nucleic acid	3,9,15,20,21 20,21	Sugar Sugar	89 percent target mRNA inhibition	19282453
SM0249	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGCU	Locked nucleic acid Altritol nucleic acid	3,9,15,20,21 5,8,11,14,17,20	Sugar Sugar	5.5 percent target mRNA inhibition	19282453
SM0262	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGCU	Alfa-L-Locked nucleic acid Altritol nucleic acid	3,9,15,20,21 5,8,11,14,17,20	Sugar Sugar	10.6 percent target mRNA inhibition	19282453
SM0294	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGCU	Locked nucleic acid Altritol nucleic acid	3,9,15,20,21 3,6,14,18,20,21	Sugar Sugar	74.3 percent target mRNA inhibition	19282453
SM0307	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGCU	Alfa-L-Locked nucleic acid Altritol nucleic acid	3,9,15,20,21 3,6,14,18,20,21	Sugar Sugar	74.7 percent target mRNA inhibition	19282453
SM0339	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,15,20,21 18,19,20 * 21	Sugar Sugar	85.2 percent target mRNA inhibition	19282453
SM0352	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Alfa-L-Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,15,20,21 18,19,20 * 21	Sugar Sugar	84.4 percent target mRNA inhibition	19282453
SM0384	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,15,20,21 2,18,19,20 * 21	Sugar Sugar	75.1 percent target mRNA inhibition	19282453
SM0397	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Alfa-L-Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,15,20,21 2,18,19,20 * 21	Sugar Sugar	66.5 percent target mRNA inhibition	19282453
SM0429	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,15,20,21 3,18,19,20 * 21	Sugar Sugar	75.7 percent target mRNA inhibition	19282453
SM0442	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Alfa-L-Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,15,20,21 3,18,19,20 * 21	Sugar Sugar	79.2 percent target mRNA inhibition	19282453
SM0474	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,15,20,21 2,9,18,19,20 * 21	Sugar Sugar	18.5 percent target mRNA inhibition	19282453
SM0487	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Alfa-L-Locked nucleic acid Hexitol nucleic acid* 2-Deoxy	3,9,15,20,21 2,9,18,19,20 * 21	Sugar Sugar	21.2 percent target mRNA inhibition	19282453
SM0519	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid 2-Aminoethoxymethyl* 2-Deoxy	3,9,15,20,21 18,19 * 21	Sugar Sugar	24.6 percent target mRNA inhibition	19282453
SM0532	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Alfa-L-Locked nucleic acid 2-Aminoethoxymethyl* 2-Deoxy	3,9,15,20,21 18,19 * 21	Sugar Sugar	58 percent target mRNA inhibition	19282453
SM0564	GACGUAAACGGCCACAAGUTCU ACUUGUGGCCGUUUACGUCGT	Locked nucleic acid 2-Aminopropoxymethyl* 2-Deoxy	3,9,15,20,21 18,19 * 21	Sugar Sugar	7.2 percent target mRNA inhibition	19282453



« previous1234next »