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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
- By modification in sense strand
- By modification position in sense strand
- By modification in antisense strand
- By modification position in antisense strand
- Reference
Total number of Results for 6,9,11 are 2
Results from 0 - 25
SMDBid | siRNA (sense/antisense) 5'>3' | Modification (sense/antisense) | Position (sense/antisense) |
Modified component (sense/antisense) |
Efficacy (%) | Reference |
SM3777 |
AACUCUACUGUGGAGUCGGTT CCGACUCCACAGUAGAGUUTT |
2-O-Methyl 2-O-Methyl |
6,9,11 8,13 |
Sugar Sugar |
68 percent target mRNA inhibition | US20120088815A1, EP2415869A1 |
SM4133 |
AACUCUACUGUGGAGUCGGTT CCGACUCCACAGUAGAGUUTT |
2-Deoxy-2-Fluoro 2-Deoxy-2-Fluoro |
6,9,11 8,10,13 |
Sugar Sugar |
65 percent target mRNA inhibition | US20120088815A1, EP2415869A1 |