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Note: (i) 0 indicates modification in opposite strand. (ii) Multiple modifications are separated bt asterisk (*).
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  • By modification in antisense strand

  • By modification position in antisense strand

  • Reference
    • Total number of Results for Pseudouridine are 8
    Results from 0 - 25
    SMDBidsiRNA (sense/antisense) 5'>3'Modification (sense/antisense)Position (sense/antisense) Modified component (sense/antisense) Efficacy (%)Reference
    SM2303
    ACAUGAAGCAGCACGACUUTT
    AAGUCGUGCUGCUUCAUGUTT
    0
    Pseudouridine
    0
    19
    0
    Base
    86 percent target mRNA inhibition
    17585051
    SM2306
    ACAUGAAGCAGCACGACUUTT
    AAGUCGUGCUGCUUCAUGUTT
    0
    Pseudouridine
    0
    10
    0
    Base
    69 percent target mRNA inhibition
    17585051
    SM2310
    ACAUGAAGCAGCACGACUUTT
    AAGUCGUGCUGCUUCAUGUTT
    Dihydrouridine
    Pseudouridine
    19
    19
    Base
    Base
    90 percent target mRNA inhibition
    17585051
    SM2312
    ACAUGAAGCAGCACGACUUTT
    AAGUCGUGCUGCUUCAUGUTT
    Dihydrouridine
    Pseudouridine
    19
    10
    Base
    Base
    89 percent target mRNA inhibition
    17585051
    SM2328
    AUACAGGCAGCAGUAACUUUTT
    AAAGUUACUGCUGCCUGUAUTT
    Dihydrouridine
    Pseudouridine
    20
    20
    Base
    Base
    77 percent target mRNA inhibition
    17585051
    SM2329
    AUACAGGCAGCAGUAACUUUTT
    AAAGUUACUGCUGCCUGUAUTT
    Dihydrouridine
    Pseudouridine
    20
    18,20
    Base
    Base
    81 percent target mRNA inhibition
    17585051
    SM2330
    AUACAGGCAGCAGUAACUUUTT
    AAAGUUACUGCUGCCUGUAUTT
    Pseudouridine* Dihydrouridine
    Pseudouridine
    2 * 20
    20
    Base
    Base
    77 percent target mRNA inhibition
    17585051
    SM2331
    AUACAGGCAGCAGUAACUUUTT
    AAAGUUACUGCUGCCUGUAUTT
    Pseudouridine* Dihydrouridine
    Pseudouridine
    2 * 20
    18,20
    Base
    Base
    81 percent target mRNA inhibition
    17585051