SMId |
Sense sequence |
Antisense sequence |
Biological activity |
SiRNA Concentration used |
Reference |
SM0046 |
NA (siEGFP mismatch control) |
NA (siEGFP mismatch control) |
0 percent target mRNA inhibition |
10 nM |
19282453 |
SM1442 |
GACGUAAACGGCCACAAGUUC |
ACUUGUGGCCGUUUACGUCGC |
85.5 percent target mRNA inhibition |
10 nM |
19282453 |
SM2172 |
AUCUGAAGAAGGAGAAAAATT |
UUUUUCUCCUUCUUCAGAUTT |
88 percent target mRNA inhibition |
0.3 nM |
19042976 |
SM2181 |
AUCUGAAGAAGGAGAAAAATT |
UCCUUUCUUUCUUUCGAAUTT |
2 percent target mRNA inhibition |
0.3 nM |
19042976 |
SM2184 |
GACGUAAACGGCCACAAGUUC |
ACUUGUGGCCGUUUACGUCGC |
NA |
400ug/kg; 4mg/kg; 10mg/kg |
19401674 |
SM2190 |
CGUACGCGGAAUACUUCGAUU |
UCGAAGUAUUCCGCGUACGUG |
4.23 percent target mRNA inhibition |
50 nM |
18575806 |
SM2191 |
GCAGCACGACUUCUUCAAGUU |
CUUGAAGAAGUCGUGCUGCUU |
77.3 percent target mRNA inhibition |
50 nM |
18575806 |
SM2200 |
UAGUUCUGUGGGGCUGUUUUU |
AAACAGCCCCACAGAACUAUU |
NA |
50 nM |
18575806 |
SM2203 |
UUCUUCGAACGUGUCACGUTT |
ACGUGACACGUUCGAAGAATT |
26 percent target mRNA inhibition |
2 nM |
17894530 |
SM2204 |
CUGGAGCAAGUUGCAAAGCAUUGGAAU |
AUUCCAAUGCUUUGCAACUUGCUCCAG |
4 percent target mRNA inhibition |
2 nM |
17894530 |
SM2205 |
GGCCUUUCACUACUCCUACGA |
GUAGGAGUAGUGAAAGGCCAG |
88 percent target mRNA inhibition |
2 nM |
17894530 |
SM2206 |
GGCCUUUCACUACUCCUACGA |
GUAGGAGUAGUGAAAGGCCAG |
48 percent target mRNA inhibition |
50 nM |
17894530 |
SM2208 |
CUGGCCUUUCACUACUCCUACGAGCAC |
GUGCUCGUAGGAGUAGUGAAAGGCCAG |
87 percent target mRNA inhibition |
2 nM |
17894530 |
SM2217 |
CUGGCCUUUCACUACUCCUACGAGCAC |
GUGCUCGUAGGAGUAGUGAAAGGCCAG |
83 percent target mRNA inhibition |
50 nM |
17894530 |
SM2235 |
GGCCUUUCACUACUCCUACGAGCAC |
GUGCUCGUAGGAGUAGUGAAAGGCCAG |
83 percent target mRNA inhibition |
0.5 nM |
17894530 |
SM2239 |
AAGGAGAUCAACAUUUUCATT |
UGAAAAUGUUGAUCUCCUUTT |
81 percent target mRNA inhibition |
2 nM |
16598842 |
SM2264 |
AAGUAAGGACCAGAGACAAA |
UUUGUCUCUGGUCCUUACUU |
IC-50 = 0.95 nM for target mRNA |
0.95 nM |
16509579 |
SM2273 |
AAGUAAGGACCAGAGACAA |
UUGUCUCUGGUCCUUACUU |
IC-50 = 0.4 nM for target mRNA |
0.4 nM |
16509579 |
SM2287 |
AAGUAAGGACCAGAGACAATT |
UUGUCUCUGGUCCUUACUUTT |
66 percent target mRNA inhibition |
2 nM |
15715458 |
SM2288 |
AAGUAAGGACCAGAGACAA |
UUGUCUCUGGUCCUUACUU |
72 percent target mRNA inhibition (IC-50 = 0.26 nM) |
2 nM |
15715458 |
SM2289 |
AAGCAAGGAGAAGCGAUAA |
UUAUCGCUUCUCGUUGCUU |
0 percent target mRNA inhibition |
2 nM |
15715458 |
SM2290 |
GGGUAAAUACAUUCUUCAUTT |
AUGAAGAAUGUAUUUACCCTT |
62 percent target mRNA inhibition |
2 nM |
15715458 |
SM2291 |
GGGUAAAUACAUUCUUCAU |
AUGAAGAAUGUAUUUACCC |
64 percent target mRNA inhibition (IC-50 = 0.81 nM) |
2 nM |
15715458 |
SM2292 |
GGGAAAGUAUCUUGUUUAU |
AUAAACAAGAUACUUUCCC |
10 percent target mRNA inhibition |
2 nM |
15715458 |
SM2314 |
ACAUGAAGCAGCACGACUUTT |
AAGUCGUGCUGCUUCAUGUTT |
90 percent target mRNA inhibition |
20 nM |
17585051 |
SM2315 |
AUGAAGCAGCACGACUUTT |
AAGUCGUGCUGCUUCAUTT |
75 percent target mRNA inhibition |
20 nM |
17585051 |
SM2316 |
GAAGCAGCACGACUUTT |
AAGUCGUGCUGCUUCTT |
5 percent target mRNA inhibition |
20 nM |
17585051 |
SM2320 |
AGCUUUGUGGAGAUGGUGGTT |
CCACCAUCUCCACAAAGCUTT |
70 percent target mRNA inhibition |
5 nM |
17585051 |
SM2323 |
AUACAGGCAGCAGUAACUUUTT |
AAAGUUACUGCUGCCUGUAUTT |
62 percent target mRNA inhibition |
1 nM |
17585051 |
SM2343 |
AUCUGAAGAAGGAGAAAAATT |
UUUUUCUCCUUCUUCAGAUTT |
91 percent target mRNA inhibition |
0.8 nM |
23764303 |
SM2348 |
CGUGACCGCACACCCAAUATT |
UAUUGGGUGUGCGGUCACGGT |
26 percent target mRNA inhibition |
10 nM |
23743442 |
SM2349 |
ACCUUGAGGCAUACUUCAATT |
UUGAAGUAUGCCUCAAGGUCG |
90 percent target mRNA inhibition |
10 nM |
23743442 |
SM2370 |
CUUCUUCGUCGAGACCAUGTT |
CAUGGUCUCGACGAAGAAGTT |
35 percent target mRNA inhibition |
0.1 nM |
23743279 |
SM2377 |
CUUCUUCGUCGAGACCAUGTT |
CAUGGUCUCGACGAAGAAGTT |
64 percent target mRNA inhibition |
1 nM |
23743279 |
SM2384 |
CUUCUUCGUCGAGACCAUGTT |
CAUGGUCUCGACGAAGAAGTT |
82 percent target mRNA inhibition |
10 nM |
23743279 |
SM2410 |
AAUCAGACAAGUUCUUCAUTT |
AUGAAGAACUUGUCUGAUUTT |
96 percent target mRNA inhibition |
1 nM |
23682800 |
SM2416 |
AAUCAGACAAGUUCUUCAUTT |
AUGAAGAACUUGUCUGAUUTT |
83 percent target mRNA inhibition |
0.1 nM |
23682800 |
SM2422 |
GGAUAUUGUCAGUCUUUAGGUU |
CCUAAAGACUGACAAUAUCCUU |
NA |
1 nM |
23449220 |
SM2435 |
GGAUAUUGUCAGUCUUUAGGUU |
CCUAAAGACUGACAAUAUCCUU |
62 percent target mRNA inhibition |
1 nM |
23449220 |
SM2441 |
GGAUAUUGUCAGUCUUUAGGUU |
CCUAAAGACUGACAAUAUCCUU |
82 percent target mRNA inhibition |
1 nM |
23449220 |
SM2447 |
AUCUGAAGAAGGAGAAAAATT |
UUUUUCUCCUUCUUCAGAUTT |
IC-50 = 0.025 nM for target mRNA |
0.025 nM |
23362010 |
SM2454 |
UAUCGAAAGAAAGAAAGGATT |
UCCUUUCUUUCUUUCGAUATT |
NA |
NA |
23362010 |
SM2478 |
GGCCUUUCACUACUCCUACGA |
GUAGGAGUAGUGAAAGGCCAG |
83 percent target mRNA inhibition |
1 nM |
22982308 |
SM2486 |
CAGCAAACCACGAUCAAUATT |
UAUUGAUCGUGGUUUGCUGTT |
71 percent target mRNA inhibition |
50 nM |
22889374 |
SM2489 |
CAGAGCAAUUGUUUACCUATT |
UAGGUAAACAAUUGCUCUGTT |
73 percent target mRNA inhibition |
50 nM |
22889374 |
SM2492 |
GGAUUGACCUCUCAUAUAATT |
UUAUAUGAGAGGUCAAUCCTT |
0 percent target mRNA inhibition |
50 nM |
22889374 |
SM2497 |
CGUUAGCAGAAACAAAAGGAG |
CUCCUUUUGUUUCUGCUAACG |
High target mRNA inhibition efficacy |
1 to 40 nM |
12771196 |
SM2498 |
CGUGAGCACAAAGAAAAUGAG |
CUCAUUUUCUUUGUGCUCACG |
Low mRNA target inhibition efficacy |
1 to 40 nM |
12771196 |
SM2503 |
UGGAAUGAACCACUGGAAUUU |
AAAUUCCAGUGGUUCAUUCCA |
High target mRNA inhibition efficacy |
1 to 40 nM |
12771196 |
SM2505 |
CGAGGGGAGUACAUCAAGAUU |
UCUUGAUGUACUCCCCUCGUU |
High target mRNA inhibition efficacy |
1 to 40 nM |
12771196 |
SM2506 |
CGAGGGGAGUACAUCAAGACC |
UCUUGAUGUACUCCCCUCGUU |
High target mRNA inhibition efficacy |
1 to 40 nM |
12771196 |
SM2509 |
GAGGGGAGUACAUCAAGAC |
CUUGAUGUACUCCCCUCUG |
Low mRNA target inhibition efficacy |
1 to 40 nM |
12771196 |
SM2533 |
UCUUGAUGUACUCCCCUCGTT |
CGAGGGGAGUACAUCAAGATT |
NA |
1 to 40 nM |
12771196 |
SM2539 |
AAUUCCAGUGGUUCAUUCC |
GGAAUGAACCACUGGAAUU |
NA |
1 to 40 nM |
12771196 |
SM2544 |
UGGCCAAUGCCAAGGAGAUUU |
AUCUCCUUGGCAUUGGCCAUU |
16 percent target mRNA inhibition |
0.1 nM |
17511001 |
SM2553 |
UGGCCAAUGCCAAGGAGAUUU |
AUCUCCUUGGCAUUGGCCAUU |
49 percent target mRNA inhibition |
1 nM |
17511001 |
SM2562 |
UGGCCAAUGCCAAGGAGAUUU |
AUCUCCUUGGCAUUGGCCAUU |
60 percent target mRNA inhibition |
5 nM |
17511001 |
SM2571 |
UGGCCAAUGCCAAGGAGAUUU |
AUCUCCUUGGCAUUGGCCAUU |
90 percent target mRNA inhibition |
20 nM |
17511001 |
SM2580 |
GCUGCGCUAUGGCGAAGACGG |
GUCUUCGCCAUAGCGCAGCTG |
High target mRNA inhibition efficacy |
0.15 mg/kg/ twice weekly |
17363479 |
SM2581 |
GCUGCGCUACUGCGAAGACGG |
GUCUUCGCAGUAGCGCAGCTG |
Low mRNA target inhibition efficacy |
0.15 mg/kg/ twice weekly |
17363479 |
SM2582 |
GCUGACCCUGAAGUUCAUCTT |
GAUGAACUUCAGGGUCAGCTT |
90 percent target mRNA inhibition |
0.25 mg/kg/d |
17363479 |
SM2585 |
CUUACGCUGAGUACUUCGATT |
UCGAAGUACUCAGCGUAAGTT |
IC-50 = 0.21 nM for target mRNA |
0.4 to 30 nM |
17163665 |
SM2592 |
CUUACGCUGAGUACUUCGATT |
UCGAAGUACUCAGCGUAAGTT |
IC-50 (Less than than 30 nM) for target mRNA |
0.4 to 30 nM |
17163665 |
SM2593 |
CUUACGCUGAGUACUUCGATT |
UCGAAGUACUCAGCGUAAGTT |
IC-50 (Less than than 30 nM) for target mRNA |
0.4 to 30 nM |
17163665 |
SM2594 |
CUUACGCUGAGUACUUCGATT |
UCGAAGUACUCAGCGUAAGTT |
IC-50 = 0.92 nM for target mRNA |
0.4 to 30 nM |
17163665 |
SM2595 |
CUUACGCUGAGUACUUCGATT |
UCGAAGUACUCAGCGUAAdTT |
82 percent target mRNA inhibition |
10 nM |
17881374 |
SM2599 |
CUUACGCUGAGUACUUCGATT |
UCGAAGUACUCAGCGUAATT |
35 percent target mRNA inhibition |
10 nM |
17881374 |
SM2600 |
CUUACGCUGAGUACUUCGATT |
UCGAAGUACUCAGCGUAATT |
35 percent target mRNA inhibition |
10 nM |
17881374 |
SM2601 |
GCGGAUCAAACCUCACCAATT |
UUGGUGAGGUUUGAUCCGCTT |
93 percent target mRNA inhibition |
17 nM |
17881374 |
SM2606 |
GACGUAAACGGCCACAAGUUC |
ACUUGUGGCCGUUUACGUCGC |
71 percent target mRNA inhibition |
10 nM |
17904849 |
SM2613 |
CGUACGCGGAAUACUUCGAUU |
UCGAAGUAUUCCGCGUACGUU |
69 percent target mRNA inhibition |
25 nM |
18094121 |
SM2614 |
CGUACGCGGAAUACUUCGAUU |
TCGAAGUAUUCCGCGUACGUU |
75 percent target mRNA inhibition |
25 nM |
18094121 |
SM2616 |
TGUACGCGGAAUACUUCGAUU |
UCGAAGUAUUCCGCGUACGUU |
65 percent target mRNA inhibition |
25 nM |
18094121 |
SM2618 |
UUAGUCGAAUGCAAGACAAUT |
UUGUCUUGCAUUCGACUAAUT |
90 percent target mRNA inhibition |
25 nM |
18094121 |
SM2622 |
UUAAGAUCUGUUAUCCGCAUT |
UGCGGAUAACAGAUCUUAAUT |
89 percent target mRNA inhibition |
25 nM |
18094121 |
SM2626 |
UUAAGAUCUGUUAUCCGCAUT |
UGCGGAUAACAGAUCUUAAUT |
70 percent target mRNA inhibition |
25 nM |
18094121 |
SM2627 |
UUAAGAUCUGUUAUCCGCAUT |
AGCGGAUAACAGAUCUUAAUT |
69 percent target mRNA inhibition |
25 nM |
18094121 |
SM2628 |
UUAAGAUCUGUUAUCCGCAUT |
UCCGGAUAACAGAUCUUAAUT |
76 percent target mRNA inhibition |
25 nM |
18094121 |
SM2629 |
UUAAGAUCUGUUAUCCGCAUT |
UGGGGAUAACAGAUCUUAAUT |
65 percent target mRNA inhibition |
25 nM |
18094121 |
SM2630 |
UUAAGAUCUGUUAUCCGCAUT |
UGCCGAUAACAGAUCUUAAUT |
60 percent target mRNA inhibition |
25 nM |
18094121 |
SM2631 |
UUAAGAUCUGUUAUCCGCAUT |
UGCGCAUAACAGAUCUUAAUT |
61 percent target mRNA inhibition |
25 nM |
18094121 |
SM2635 |
CGAUGUGUCUAUUGAAGAUUC |
AUCUUCAAUAGACACAUCGGC |
3 percent target mRNA inhibition |
0.002 nM |
18367449 |
SM2637 |
CGAUGUGUCUAUUGAAGAUUC |
AUCUUCAAUAGACACAUCGGC |
14 percent target mRNA inhibition |
0.02 nM |
18367449 |
SM2639 |
CGAUGUGUCUAUUGAAGAUUC |
AUCUUCAAUAGACACAUCGGC |
55 percent target mRNA inhibition |
0.2 nM |
18367449 |
SM2641 |
CGAUGUGUCUAUUGAAGAUUC |
AUCUUCAAUAGACACAUCGGC |
68 percent target mRNA inhibition |
2 nM |
18367449 |
SM2644 |
CUUACGCUGAGUACUUCGATT |
UCGAAGUACUCAGCGUAAGTT |
88 percent target mRNA inhibition |
25 nM |
19233658 |
SM2658 |
UCGAAGUAUUCCGCGUACGTT |
CGUACGCGGAAUACUUCGATT |
83 percent target mRNA inhibition |
100 nM |
19325750 |
SM2662 |
UCGAAGUAUUCCGCGUACGTT |
CGUACGCGGAAUACUUCGATT |
80 percent target mRNA inhibition |
10 nM |
19325750 |
SM2666 |
UCGAAGUAUUCCGCGUACGTT |
CGUACGCGGAAUACUUCGATT |
75 percent target mRNA inhibition |
1 nM |
19325750 |
SM2670 |
UCGAAGUAUUCCGCGUACGTT |
CGUACGCGGAAUACUUCGATT |
64 percent target mRNA inhibition |
0.1 nM |
19325750 |
SM2674 |
CUAAGGACCUAACAAAGUUUU |
AACUUUGUUAGGUCCUUAGUU |
NA |
10 nM |
20005874 |
SM2675 |
CUAAGGACCUAACAAAGUUUU |
AACUUUGUUAGGUCCUUAGUU |
NA |
10 nM |
20005874 |
SM2676 |
CUAAGGACCUAACAAAGUUUU |
AACUUUGUUAGGUCCUUAGUU |
0 percent target mRNA inhibition |
10 nM |
20005874 |
SM2683 |
CUAAGGACCUAACAAAGUUUU |
AACUUUGUUAGGUCCUUAGUU |
2.75 (log-10 CVB-3 titre pfu/ml) |
10 nM |
20005874 |
SM2684 |
CUAAGGACCUAACAAAGUUUU |
AACUUUGUUAGGUCCUUAGUU |
2.55 (log-10 CVB-3 titre pfu/ml) |
10 nM |
20005874 |
SM2685 |
CUAAGGACCUAACAAAGUUUUU |
AACUUUGUUAGGUCCUUAGUU |
2.9 (log-10 CVB-3 titre pfu/ml) |
10 nM |
20005874 |
SM2686 |
CUAAGGACCUAACAAAGUUUU |
AACUUUGUUAGGUCCUUAGUU |
4 (log-10 CVB-3 titre pfu/ml) |
10 nM |
20005874 |
SM2687 |
UUCUCCGAACGUGUCACGUUUU |
ACGUGACACGUUCGGAGAAUUU |
NA |
10 nM |
20005874 |
SM2706 |
UCGAAGUAUUCCGCGUACGTT |
CGUACGCGGAAUACUUCGATT |
78 percent target mRNA inhibition |
0.032 nM |
20485810 |
SM2713 |
UCGAAGUAUUCCGCGUACGTT |
CGUACGCGGAAUACUUCGATT |
74 percent target mRNA inhibition |
0.032 nM |
20485810 |
SM2720 |
UCGAAGUAUUCCGCGUACGTT |
CGUACGCGGAAUACUUCGATT |
75 percent target mRNA inhibition |
0.32 nM |
20485810 |
SM2727 |
UCGAAGUAUUCCGCGUACGTT |
CGUACGCGGAAUACUUCGATT |
72 percent target mRNA inhibition |
0.32 nM |
20485810 |
SM2734 |
UCGAAGUAUUCCGCGUACGTT |
CGUACGCGGAAUACUUCGATT |
72 percent target mRNA inhibition |
0.32 nM |
20485810 |
SM2741 |
UCGAAGUAUUCCGCGUACGTT |
CGUACGCGGAAUACUUCGATT |
67 percent target mRNA inhibition |
0.32 nM |
20485810 |
SM2748 |
UCGAAGUAUUCCGCGUACGTT |
CGUACGCGGAAUACUUCGATT |
77 percent target mRNA inhibition |
0.32 nM |
20485810 |
SM2755 |
UCGAAGUAUUCCGCGUACGTT |
CGUACGCGGAAUACUUCGATT |
69 percent target mRNA inhibition |
0.32 nM |
20485810 |
SM2762 |
UCGAAGUAUUCCGCGUACGTT |
CGUACGCGGAAUACUUCGATT |
66 percent target mRNA inhibition |
0.32 nM |
20485810 |
SM2769 |
UCGAAGUAUUCCGCGUACGTT |
CGUACGCGGAAUACUUCGATT |
70 percent target mRNA inhibition |
0.32 nM |
20485810 |
SM2776 |
CUUACGCUGAGUACUUCGATT |
TCGAAGUACUCAGCGUAAGTT |
NA |
0.002 to 8.0 nM |
20610434 |
SM2821 |
CUUACGCUGAGUACUUCGATT |
TCGAAGUACUCAGCGUAAGTT |
IC-50 = 0.144 nM for target mRNA |
0.002 to 8.0 nM |
20610434 |
SM2827 |
CUUACGCUGAGUACUUCGAAA |
UCGAAGUACUCAGCGUAAGUG |
IC-50 = 0.144 nM for target mRNA |
0.002 to 8.0 nM |
20610434 |
SM2837 |
AAGUAAGGACCAGAGACAATT |
UUGUCUCUGGUCCUUACUUTT |
IC-50 = 0.179 nM for target mRNA |
0.002 to 8.0 nM |
20610434 |
SM2838 |
AAGUAAGGACCAGAGACAATT |
UUGUCUCUGGUCCUUACUUTT |
IC-50 = 0.092 nM for target mRNA |
0.002 to 8.0 nM |
20610434 |
SM2839 |
AAGUAAGGACCAGAGACAATT |
UUGUCUCUGGUCCUUACUUTT |
IC-50 = 0.076 nM for target mRNA |
0.002 to 8.0 nM |
20610434 |
SM2840 |
AAGUAAGGACCAGAGACAATT |
UUGUCUCUGGUCCUUACUUTT |
IC-50 = 0.066 nM for target mRNA |
0.002 to 8.0 nM |
20610434 |
SM2841 |
AAGUAAGGACCAGAGACAATT |
UUGUCUCUGGUCCUUACUUTT |
IC-50 = 0.052 nM for target mRNA |
0.002 to 8.0 nM |
20610434 |
SM2842 |
AAGUAAGGACCAGAGACAATT |
UUGUCUCUGGUCCUUACUUTT |
IC-50 = 0.021 nM for target mRNA |
0.002 to 8.0 nM |
20610434 |
SM2843 |
AAGUAAGGACCAGAGACAATT |
UUGUCUCUGGUCCUUACUUTT |
IC-50 = 0.053 nM for target mRNA |
0.002 to 8.0 nM |
20610434 |
SM2848 |
CAAGUGUCAUCACACUGAATT |
UUCAGUGUGAUGACACUUGTT |
61 percent target mRNA inhibition |
10 nM |
21942264 |
SM2868 |
CAAGUGUCAUCACACUGAATT |
UUCAGUGUGAUGACACUUGTT |
81 percent target mRNA inhibition |
10 nM |
21942264 |
SM2888 |
CAAGUGUCAUCACACUGAATT |
UUCAGUGUGAUGACACUUGTT |
81 percent target mRNA inhibition |
10 nM |
21942264 |
SM2908 |
GACGUAAACGGCCACAAGUUC |
ACUUGUGGCCGUUUACGUCGC |
High target mRNA inhibition efficacy |
1 nM |
21687525 |
SM2915 |
GACUUAGACUGACACAAGUUC |
CUUGUGUCAGUCUAAGUCGC |
High target mRNA inhibition efficacy |
1 nM |
21687525 |
SM2916 |
GACGUAAACGGCCACAAGUUC |
ACUUGUGGCCGUUUACGUCGC |
High target mRNA inhibition efficacy |
5 nM |
21687525 |
SM2923 |
GACUUAGACUGACACAAGUUC |
CUUGUGUCAGUCUAAGUCGC |
High target mRNA inhibition efficacy |
5 nM |
21687525 |
SM2924 |
GACGUAAACGGCCACAAGUUC |
ACUUGUGGCCGUUUACGUCGC |
High target mRNA inhibition efficacy |
25 nM |
21687525 |
SM2931 |
GACUUAGACUGACACAAGUUC |
CUUGUGUCAGUCUAAGUCGC |
High target mRNA inhibition efficacy |
25 nM |
21687525 |
SM2932 |
GACGUAAACGGCCACAAGUUC |
ACUUGUGGCCGUUUACGUCGC |
High target mRNA inhibition efficacy |
0.25 mg/kg/day |
21687525 |
SM2939 |
GACUUAGACUGACACAAGUUC |
CUUGUGUCAGUCUAAGUCGC |
High target mRNA inhibition efficacy |
0.25 mg/kg/day |
21687525 |
SM2940 |
AAGCUGACCCUGAAGUUCAUCUGCACC |
GGUGCAGAUGAACUUCAGGGUCAGCUU |
82 percent target mRNA inhibition |
1.56 nM |
21739319 |
SM2946 |
AAGCUGACCCUGAAGUUCAUCUGCACC |
GGUGCAGAUGAACUUCAGGGUCAGCUU |
91 percent target mRNA inhibition |
1.56 nM |
21739319 |
SM2952 |
GUAUGACCGACUACGCGUATT |
UUCAGUGUGAUGACACUUGTT |
95 percent target mRNA inhibition (IC-50 = 0.123 nM) |
10 nM |
19917641 |
SM2976 |
GCAGCACGACUUCUUCAAGTT |
CUUGAAGAAGUCGUGCUGCTT |
93 percent target mRNA inhibition |
50 nM |
12923253 |
SM3002 |
GCAGCACGACUUCUUCAAGTT |
CUUGAAGAAGUCGUGCUGCTT |
35 percent target mRNA inhibition |
50 nM |
12923253 |
SM3003 |
GCAGCACGACUUCUUCAAGTT |
CUUGAAGAAGUCGUGCUGCTT |
77 percent target mRNA inhibition |
50 nM |
12923253 |
SM3008 |
GACGUAAACGGCCACAAGUUCU |
ACUUGUGGCCGUUUACGUCGCU |
89 percent target mRNA inhibition |
10 nM |
22287630 |
SM3016 |
GUUCACCUUGAUGCCGUUCUU |
GAACGGCAUCAAGGUGAACUU |
78 percent target mRNA inhibition |
25 nM |
15545637 |
SM3031 |
GUUCACCUUGAUGCCGUUCUU |
GAACGGAACUACGGUGAACUU |
0 percent target mRNA inhibition |
25 nM |
15545637 |
SM3032 |
GUUCACCUUGAUGCCGUUCUU |
GAACGGAACUACGGUGAACUU |
0 percent target mRNA inhibition |
25 nM |
15545637 |
SM3033 |
GUUCACCUUGAUGCCGUUCUU |
GCACGACUUCUUCAAGUCCUU |
65 percent target mRNA inhibition |
25 nM |
15545637 |
SM3036 |
GUUCACCUUGAUGCCGUUCUU |
GCACGCUUCUUCAAAGUCCUU |
0 percent target mRNA inhibition |
25 nM |
15545637 |
SM3037 |
CUUACGCUGAGUACUUCGATT |
UCGAAGUACUCAGCGUAAGTT |
95 percent target mRNA inhibition |
13 nM |
15653644 |
SM3038 |
AUCUGAAGAAGGAGAAAAATT |
UUUUUCUCCUUCUUCAGAUTT |
90 percent target mRNA inhibition |
13 nM |
15653644 |
SM3039 |
UGAGAGAAAGCACAGAAAATT |
UUUUCUGUGCUUUCUCUCATT |
73 percent target mRNA inhibition |
13 nM |
15653644 |
SM3040 |
AAACAUGCAGAAAAYGCUGTT |
CAGCAUUUUCUGCAUGUUUTT |
43 percent target mRNA inhibition |
13 nM |
15653644 |
SM3041 |
UCCAGAACAAAACCAAACGGTT |
CCGUUUGGUUUGUUCUGGATT |
28 percent target mRNA inhibition |
13 nM |
15653644 |
SM3042 |
GGACGAGGAAGGCAAUUUATT |
UAAAUUGCCUUCCUCAUCCTT |
48 percent target mRNA inhibition |
13 nM |
15653644 |
SM3043 |
CUGGUACGAUUUCGGUGAUTT |
AGCACCGAAAUCGUACCAGTT |
0 percent target mRNA inhibition |
13 nM |
15653644 |
SM3044 |
ACUGUCAAACCCGGUAAUUTT |
AAUUACCGGGUUUGACAGUTT |
15 percent target mRNA inhibition |
13 nM |
15653644 |
SM3089 |
GCUUGAAGUCUUUAAUUAATT |
UUAAUUAAAGACUUCAAGCGG |
IC-50 = 0.16 nM for target mRNA |
0.16 nM |
17284457 |
SM3090 |
GCUUGAAGUCUUUAAUUAATT |
UUAAUUAAAGACUUCAAGCGG |
IC-50 = 0.04 nM for target mRNA |
1.04 nM |
17284457 |
SM3099 |
GCUUGAAGUCUUUAAUUAATT |
UUAAUUAAAGACUUCAAGCGG |
IC-50 = 0.16 nM for target mRNA |
0.16 nM |
17284457 |
SM3100 |
GCUUGAAGUCUUUAAUUAAGG |
UUAAUUAAAGACUUCAAGCGG |
IC-50 = 0.87 nM for target mRNA |
0.87 nM |
17284457 |
SM3110 |
AUCUGAAGAAGGAGAAAAATT |
UUUUUCUCCUUCUUCAGAUTT |
95 percent target mRNA inhibition |
2.1 ng |
18624291 |
SM3115 |
ACCUGACGUUGUACAAAUUTT |
AAUUUGUACAACGUCAGGUTT |
85 percent target mRNA inhibition |
2.1 ng |
18624291 |
SM3129 |
CUUCCUCUCUUUCUCUCCCUUGUGA |
UCACAAGGGAGAGAAAGAGAGGAAGGA |
0 percent target mRNA inhibition |
10 nM |
18637735 |
SM3130 |
GCACCAGAGCCAAUGGAACUUGATG |
CAUCAAGUUCCAUUGGCUCUGGUGCUU |
93 percent target mRNA inhibition |
10 nM |
18637735 |
SM3147 |
CUUCCUCUCUUUCUCUCCCUUGUGA |
UCACAAGGGAGAGAAAGAGAGGAAGGA |
0 percent target mRNA inhibition |
1 nM |
18637735 |
SM3148 |
GCACCAGAGCCAAUGGAACUUGATG |
CAUCAAGUUCCAUUGGCUCUGGUGCUU |
95 percent target mRNA inhibition |
1 nM |
18637735 |
SM3165 |
CUUCCUCUCUUUCUCUCCCUUGUGA |
UCACAAGGGAGAGAAAGAGAGGAAGGA |
0 percent target mRNA inhibition |
0.1 nM |
18637735 |
SM3166 |
GCACCAGAGCCAAUGGAACUUGATG |
CAUCAAGUUCCAUUGGCUCUGGUGCUU |
87 percent target mRNA inhibition |
0.1 nM |
18637735 |
SM3183 |
GCCAGACUUUGUUGGAUUUGAAATT |
AAUUUCAAAUCCAACAAAGUCUGGCUU |
0 percent target mRNA inhibition |
0.1 nM |
18637735 |
SM3184 |
ACCCUGAAGUUCAUCUGCACCACCG |
CGGUGGUGCAGAUGAACUUCAGGGUCA |
34 percent target mRNA inhibition |
0.1 nM |
18637735 |
SM3189 |
GCCAGACUUUGUUGGAUUUGAAATT |
AAUUUCAAAUCCAACAAAGUCUGGCUU |
0 percent target mRNA inhibition |
1 nM |
18637735 |
SM3190 |
ACCCUGAAGUUCAUCUGCACCACCG |
CGGUGGUGCAGAUGAACUUCAGGGUCA |
96 percent target mRNA inhibition |
1 nM |
18637735 |
SM3195 |
GCCAGACUUUGUUGGAUUUGAAATT |
AAUUUCAAAUCCAACAAAGUCUGGCUU |
0 percent target mRNA inhibition |
10 nM |
18637735 |
SM3196 |
ACCCUGAAGUUCAUCUGCACCACCG |
CGGUGGUGCAGAUGAACUUCAGGGUCA |
98 percent target mRNA inhibition |
10 nM |
18637735 |
SM3201 |
CUUCCUCUCUUUCUCUCCCUUGUGA |
UCACAAGGGAGAGAAAGAGAGGAAGGA |
0 percent target mRNA inhibition |
10 nM |
18637735 |
SM3202 |
GCCAGACUUUGUUGGAUUUUGAAATT |
AAUUUCAAAUCCAACAAAGUCUGGCUU |
81 percent target mRNA inhibition |
0.1 nM |
18637735 |
SM3205 |
GCCAGACUUUGUUGGAUUUUGAAATT |
AAUUUCAAAUCCAACAAAGUCUGGCUU |
93 percent target mRNA inhibition |
1 nM |
18637735 |
SM3208 |
GCCAGACUUUGUUGGAUUUUGAAATT |
AAUUUCAAAUCCAACAAAGUCUGGCUU |
96 percent target mRNA inhibition |
10 nM |
18637735 |
SM3211 |
GCCAGUAAUUCAGCAGUUUGAACAA |
UUGUUCAAACUGCUGAAUUACUGGCUG |
43 percent target mRNA inhibition |
0.01 nM |
18637735 |
SM3213 |
CACCAAUGAAUUCUCGAUUGAUGTG |
CACAUCAAUCGAGAAUUCAUUGGUGUU |
NA |
NA |
18637735 |
SM3215 |
GCAUUCCAGAGAAAGCGUUUAAUTT |
AAAUUAAACGCUUUCUCUGGAAUGCCU |
54 percent target mRNA inhibition |
0.01 nM |
18637735 |
SM3217 |
GCCAGUAAUUCAGCAGUUUGAACAA |
UUGUUCAAACUGCUGAAUUACUGGCUG |
78 percent target mRNA inhibition |
0.05 nM |
18637735 |
SM3219 |
CACCAAUGAAUUCUCGAUUGAUGTG |
CACAUCAAUCGAGAAUUCAUUGGUGUU |
NA |
NA |
18637735 |
SM3221 |
GCAUUCCAGAGAAAGCGUUUAAUTT |
AAAUUAAACGCUUUCUCUGGAAUGCCU |
83 percent target mRNA inhibition |
0.05 nM |
18637735 |
SM3223 |
GCCAGUAAUUCAGCAGUUUGAACAA |
UUGUUCAAACUGCUGAAUUACUGGCUG |
89 percent target mRNA inhibition |
0.0250 nM |
18637735 |
SM3225 |
CACCAAUGAAUUCUCGAUUGAUGTG |
CACAUCAAUCGAGAAUUCAUUGGUGUU |
NA |
NA |
18637735 |
SM3227 |
GCAUUCCAGAGAAAGCGUUUAAUTT |
AAAUUAAACGCUUUCUCUGGAAUGCCU |
87 percent target mRNA inhibition |
0.025 nM |
18637735 |
SM3229 |
GUGGGAGCGCGUGAUGAACTT |
GUUCAUCACGCGCUCCCACTT |
0 percent target mRNA inhibition |
50 nM |
18776474 |
SM3230 |
GCAGCACGACUUCUUCAAGTT |
CUUGAAGAAGUCGUGCUGCTT |
80 percent target mRNA inhibition |
50 nM |
18776474 |
SM3234 |
GCAGCACGACUUCUUCAAGTT |
CUUGAAGAAGUCGUGCUGCTT |
77 percent target mRNA inhibition |
20 nM |
21687522 |
SM3235 |
GUGGGAGCGCGUGAUGAACTT |
GUUCAUCACGCGCUCCCACTT |
0 percent target mRNA inhibition |
20 nM |
21687522 |
SM3248 |
GCAGCACGACUUCUUCAAGTT |
CUUGAAGAAGUCGUGCUGCTT |
52 percent target mRNA inhibition |
5 nM |
21687522 |
SM3249 |
GUGGGAGCGCGUGAUGAACTT |
GUUCAUCACGCGCUCCCACTT |
0 percent target mRNA inhibition |
5 nM |
21687522 |
SM3262 |
GCAGCACGACUUCUUCAAGTT |
CUUGAAGAAGUCGUGCUGCTT |
26 percent target mRNA inhibition |
2 nM |
21687522 |
SM3263 |
GUGGGAGCGCGUGAUGAACTT |
GUUCAUCACGCGCUCCCACTT |
0 percent target mRNA inhibition |
2 nM |
21687522 |
SM3276 |
GUAUUGACAGCUAUUCGAATT |
UUCGAAUAGCUGUCAAUACTT |
36 percent target mRNA inhibition |
50 nM |
17264131 |
SM3307 |
GCACGAAUCCUAAACCUCAUU |
UGAGGUUUAGGAUUCGUGCUU |
89 percent target mRNA inhibition |
20 nM |
19948766 |
SM3308 |
GCACGAAUCCUAAACCUCACAAUAUGAGGUUUAGGAUUCGUGCUU |
0 |
53 percent target mRNA inhibition |
20 nM |
19948766 |
SM3309 |
UGAGGUUUAGGAUUCGUGCUUGCACGAAUCCUAAACCUCA |
0 |
90 percent target mRNA inhibition (IC-50 = 0.0035 nM) |
20 nM |
19948766 |
SM3310 |
UUUUUCUUUGAGGUUUAGGUUCCUAAACCUCAAAGAAAAAUU |
0 |
90 percent target mRNA inhibition |
20 nM |
19948766 |
SM3311 |
UGAGGUUUAGGAUUCGUGUUCACGAAUCCUAAACCUCA |
0 |
NA |
20 nM |
19948766 |
SM3312 |
AUUCGUGCUCAUGGUGCACUUGUGCACCAUGAGCACGAAUUU |
0 |
74 percent target mRNA inhibition |
20 nM |
19948766 |
SM3313 |
ACGAAUCCUAAACCUCA |
UGAGGUUUAGGAUUCGUGC |
NA |
20 nM |
19948766 |
SM3314 |
UGAGGUUUAGGAUUCGUGCUUGCACGAAUCCUAAACCUCAUU |
0 |
NA |
20 nM |
19948766 |
SM3321 |
UGAGGUUUAGGAUUCGUGCTTGCACGAAUCCUAAACCUCA |
0 |
95 percent target mRNA inhibition |
20 nM |
19948766 |
SM3337 |
ACGAAUCCUAAACCUCA |
UGAGGUUUAGGAUUCGUGC |
95 percent target mRNA inhibition |
20 nM |
19948766 |
SM3350 |
AGACGAGCUGAGCGAGAAGTT |
TTUCUGCUCGACUCGCUCUUC |
NA |
200 nM |
12834349 |
SM3369 |
CUUACGCUGAGUACUUCGAUU |
UUUGAAUGCGACUCAUGAAGCU |
NA |
20 nM |
18066804 |
SM3372 |
GUGGUAUUGUUCCUCCUAATT |
UUAGGAGGAACAAUACCACTT |
IC-50 = 1.5 nM for target mRNA |
0.6 to 45 nM |
16343994 |
SM3375 |
GUGAUCAGACUCAAUACGAAU |
AUUCGUAUUGAGUCUGAUCACAC |
IC-50 = 1.5 nM for target mRNA |
0.6 to 45 nM |
16343994 |
SM3377 |
GUCAUCACACUGAAUACCAAU |
AUUGGUAUUCAGUGUGAUGACAC |
IC-50 = 1.5 nM for target mRNA |
0.6 to 45 nM |
16343994 |
SM3381 |
UUGAUGUGUUUAGUCGCUAUU |
UAGCGACUAAACACAUCAAUU |
IC-50 = 1.5 nM for target mRNA |
0.6 to 45 nM |
16343994 |
SM3383 |
TTAUCUCCAUGCACGACUCCG |
UAGAGGUACGUGCUGAGGCTT |
34 percent target mRNA inhibition |
25 and 50 nM |
17979170 |
SM3388 |
GGACCACCGCAUCUCUACATT |
GGACCACCGCAUCUCUACATT |
NA |
10 nM |
20704260 |
SM3405 |
CGAUGUGUCUAUUGAAGAUUC |
CGGCUACACAGAUAACUUCUA |
NA |
20 nM |
18367449 |
SM3440 |
AGCGCUUAAAGGGCGAGAAGAUU |
UCUUCUCGCCCUUUAAGCGCUUU |
84 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3458 |
AGCGCUUAAAGGGCGAGAAGAUU |
UCUUCUCGCCCUUUAAGCGCUUU |
85 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3465 |
AACCCACCACAGCUAGAACUU |
AAGUUCUAGCUGUGGUGGGUU |
86 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3483 |
AACCCACCACAGCUAGAACUU |
AAGUUCUAGCUGUGGUGGGUU |
78 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3503 |
AGAAGGACUACUAACCUCCTT |
GGAGGUUAGUAGUCCUUCUTT |
83 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3507 |
GGACUACUAACCUCCAGUUTT |
AACUGGAGGUUAGUAGUCCTT |
69 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3511 |
GAAACUGGUACUUUCCCCCTT |
GGGGGAAAGUACCAGUUUCTT |
69 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3515 |
UUUCCCCCAGGUAACGAUUTT |
AAUCGUUACCUGGGGGAAATT |
70 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3519 |
CCCCAGGUAACGAUUUUCUTT |
AGAAAAUCGUUACCUGGGGTT |
86 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3523 |
GGGAAACUGAAAGGCUAUGTT |
CAUAGCCUUUCAGUUUCCCTT |
57 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3527 |
GCGAGCAGAGAAUCUACCUTT |
AGGUAGAUUCUCUGCUCGCTT |
97 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3531 |
GCAGAGAAUCUACCUUUCCTT |
GGAAAGGUAGAUUCUCUGCTT |
79 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3535 |
ACCUUUCCACUUCUAAGCCTT |
GGCUUAGAAGUGGAAAGGUTT |
84 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3539 |
CUAAGCCUGUUUCUUCCUCTT |
GAGGAAGAAACAGGCUUAGTT |
90 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3543 |
GAAGAUAGGAAGGGGCUUCTT |
GAAGCCCCUUCCUAUCUUCTT |
55 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3547 |
AAUAAGCAGCUCGCGCUCCTT |
GGAGCGCGAGCUGCUUAUUTT |
73 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3551 |
UAGCCAGAGCCAAAGAAGCTT |
GCUUCUUUGGCUCUGGCUATT |
93 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3555 |
AACAGUCCUUAGCUACGCUTT |
AGCGUAGCUAAGGACUGUUTT |
49 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3559 |
CUAGAGGAUCUUGAAGACCTT |
GGUCUUCAAGAUCCUCUAGTT |
72 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3563 |
AUCGACCUGAAGGAGUACGTT |
CGUACUCCUUCAGGUCGAUTT |
52 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3567 |
GAUAGGAAGGGGCUUCAGCTT |
GCUGAAGCCCCUUCCUAUCTT |
53 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3571 |
AGUCCCUGGAGCCUUAAACTT |
GUUUAAGGCUCCAGGGACUTT |
72 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3575 |
AGCCACAUUUCUAGGAGAUTT |
AUCUCCUAGAAAUGUGGCUTT |
39 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3579 |
GAUUCCAAACCCCACUAUCTT |
GAUAGUGGGGUUUGGAAUCTT |
73 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3583 |
GAUACUUCUGGUUCCCUCCTT |
GGAGGGAACCAGAAGUAUCTT |
53 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3587 |
AGAGAAGGGCGUCUCUACATT |
UGUAGAGACGCCCUUCUCUTT |
83 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3591 |
AGUUUCUAGGGCCGUGGCCTT |
GGCCACGGCCCUAGAAACUTT |
90 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3595 |
GAAGAGUUAACCCGGGACUTT |
AGUCCCGGGUUAACUCUUCTT |
62 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3599 |
CCGCCCGGCGGCGCCUUUATT |
UAAAGGCGCCGCCGGGCGGTT |
95 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3603 |
ACCGACGAUUCUUCUACUCTT |
GAGUAGAAGAAUCGUCGGUTT |
73 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3607 |
GGUAGAAUAGGUUUUCCCCTT |
GGGGAAAACCUAUUCUACCTT |
54 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3611 |
UCCCUUCCACCGCCAUAUUTT |
AAUAUGGCGGUGGAAGGGATT |
58 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3615 |
CGAGUGUCUAACGGGAGCCTT |
GGCUCCCGUUAGACACUCGTT |
70 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3619 |
GACCACGAAGAGUUAACCCTT |
GGGUUAACUCUUCGUGGUCTT |
91 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3623 |
AGUUAACCCGGGACUUGGATT |
UCCAAGUCCCGGGUUAACUTT |
97 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3627 |
AUCACAAACCCCUAGAGGGTT |
CCCUCUAGGGGUUUGUGAUTT |
35 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3631 |
AAACCCCUAGAGGGCAAGUTT |
ACUUGCCCUCUAGGGGUUUTT |
81 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3635 |
UCCGGCUAACUCUGAGGACTT |
GUCCUCAGAGUUAGCCGGATT |
95 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3639 |
CGACGAUUCUUCUACUCAATT |
UUGAGUAGAAGAAUCGUCGTT |
72 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3643 |
UAAACUUUGGGGAAGGGAGTT |
CUCCCUUCCCCAAAGUUUATT |
73 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3647 |
AGCGGGGUAUGAAGAGCUUTT |
AAGCUCUUCAUACCCCGCUTT |
95 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3651 |
CUCCCCAGUCUCUCUUAAATT |
UUUAAGAGAGACUGGGGAGTT |
72 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3655 |
GAAUAACCUGAACGUCACCTT |
GGUGACGUUCAGGUUAUUCTT |
59 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3659 |
ACGUCACCGAGGAGAAGUATT |
UACUUCUCCUCGGUGACGUTT |
65 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3663 |
AGAAGUACCAGGAGGCGUUTT |
AACGCCUCCUGGUACUUCUTT |
75 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3667 |
AGCCCAGAUAGCUCUUCAGTT |
CUGAAGAGCUAUCUGGGCUTT |
72 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3671 |
AAACCUCAGCCCUAACGGUTT |
ACCGUUAGGGCUGAGGUUUTT |
94 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3675 |
UUAAGGAGAAGCUGACGGCTT |
GCCGUCAGCUUCUCCUUAATT |
73 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3679 |
AAGGAACGGGGACACUUACTT |
GUAAGUGUCCCCGUUCCUUTT |
44 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3683 |
GGAGCACGCUUACUACCUUTT |
AAGGUAGUAAGCGUGCUCCTT |
77 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3687 |
GGCGGGCUCUUUCCUAUUCTT |
GAAUAGGAAAGAGCCCGCCTT |
77 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3691 |
CCGAGAGCUCUCCUACCUUTT |
AAGGUAGGAGAGCUCUCGGTT |
80 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3695 |
CUCUCCUACCUUCUCCUCUTT |
AGAGGAGAAGGUAGGAGAGTT |
83 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3699 |
CUACCUUCUCCUCUUCUCCTT |
GGAGAAGAGGAGAAGGUAGTT |
75 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3703 |
AGCCUCCAAACUCCUAGCUTT |
AGCUAGGAGUUUGGAGGCUTT |
43 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3707 |
UCCUAGCUGUCUUGUCCCUTT |
AGGGACAAGACAGCUAGGATT |
75 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3711 |
AUACUUGGCGGGCUCUUUCTT |
GAAAGAGCCCGCCAAGUAUTT |
53 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3715 |
GGGGCUCUUCUACAUUCCCTT |
GGGAAUGUAGAAGAGCCCCTT |
77 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3719 |
GAGUAUUUCCGCUGGAACUTT |
AGUUCCAGCGGAAAUACUCTT |
87 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3723 |
GCUGAGGAAAGGGACAUCUTT |
AGAUGUCCCUUUCCUCAGCTT |
85 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3727 |
GUACUCUGAUGAGGAAGAGTT |
CUCUUCCUCAUCAGAGUACTT |
75 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3731 |
GGCCAAAGUAAUCGUGGUUTT |
AACCACGAUUACUUUGGCCTT |
93 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3735 |
GUCUAUGCCAAGAAGGGAGTT |
CUCCCUUCUUGGCAUAGACTT |
81 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3739 |
UCUACACCGCGCCCCCCUCTT |
GAGGGGGGCGCGGUGUAGATT |
84 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3743 |
CGCCCCCCUCAAGCUACCGTT |
CGGUAGCUUGAGGGGGGCGTT |
81 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3747 |
GCUACCGCAACCACGAGCUTT |
AGCUCGUGGUUGCGGUAGCTT |
47 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3751 |
CUCCUUCAUUCCAGCCUAUTT |
AUAGGCUGGAAUGAAGGAGTT |
84 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3755 |
AGAAAAGCAGCGAUACGCUTT |
AGCGUAUCGCUGCUUUUCUTT |
78 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3759 |
GGAGCUAGACGGGUACGAGTT |
CUCGUACCCGUCUAGCUCCTT |
93 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3763 |
CGGGUACGAGCCGGAACCUTT |
AGGUUCCGGCUCGUACCCGTT |
70 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3767 |
ACGGCUCGCUACCCUCGACTT |
GUCGAGGGUAGCGAGCCGUTT |
87 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3771 |
AGAGGACCUAGAAGGCGGCTT |
GCCGCCUUCUAGGUCCUCUTT |
97 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3775 |
AACUCUACUGUGGAGUCGGTT |
CCGACUCCACAGUAGAGUUTT |
77 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3779 |
AGAAACGCAGUAAUCCGGATT |
UCCGGAUUACUGCGUUUCUTT |
86 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3783 |
AGUAAUCCGGACUCAACUCTT |
GAGUUGAGUCCGGAUUACUTT |
72 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3787 |
GAGGAAGAUGAGUUGUACCTT |
GGUACAACUCAUCUUCCUCTT |
81 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3791 |
AGAUGUUCUCGUAAGGACGTT |
CGUCCUUACGAGAACAUCUTT |
62 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3795 |
UCUCGUAAGGACGAAACGATT |
UCGUUUCGUCCUUACGAGATT |
58 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3799 |
GCUGUAACCUCGGAGAGUUTT |
AACUCUCCGAGGUUACAGCTT |
71 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3803 |
CCUCGGAGAGUUCUACUCUTT |
AGAGUAGAACUCUCCGAGGTT |
87 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3807 |
GCAAGUGGCAAGAGGAUUATT |
UAAUCCUCUUGCCACUUGCTT |
71 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3811 |
AUGGGAGAAGUAGUCCCCCTT |
GGGGGACUACUUCUCCCAUTT |
86 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3815 |
AAGUAGUCCCCCUUGAAGATT |
UCUUCAAGGGGGACUACUUTT |
75 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3819 |
GGUAGGGUUGAAGAGACUUTT |
AAGUCUCUUCAACCCUACCTT |
97 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3823 |
AGCGCUUAAAGGGCGAGAAGATT |
UCUUCUCGCCCUUUAAGCGCUTT |
86 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3827 |
GGCCUUUCUCUCUAGAUAUTT |
AUAUCUAGAGAGAAAGGCCTT |
91 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3831 |
GCCUCUCUAUCCUUAGCUUTT |
AAGCUAAGGAUAGAGAGGCTT |
49 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3835 |
AAGGACCUAGAGGAGUCACTT |
GUGACUCCUCUAGGUCCUUTT |
90 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3839 |
CUGACCGGAAGCGCUUAAATT |
UUUAAGCGCUUCCGGUCAGTT |
87 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3843 |
UUAAAGGGCGAGAAGACCGTT |
CGGUCUUCUCGCCCUUUAATT |
89 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3847 |
GAAGAGCCUACACAACCCUTT |
AGGGUUGUGUAGGCUCUUCTT |
77 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3851 |
CUAGAGGAUCUUGAAGACCTT |
GGUCUUCAAGAUCCUCUAGTT |
83 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3855 |
ACAUAGAGGAAGACGCGGATT |
UCCGCGUCUUCCUCUAUGUTT |
91 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3859 |
AUCGUCGUCAGGGUAAGGUTT |
ACCUUACCCUGACGACGAUTT |
50 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3863 |
CUCUGGCCUUUCUCUCUAGTT |
CUAGAGAGAAAGGCCAGAGTT |
48 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3867 |
GACAAGGGAAGGUUAGCCUTT |
AGGCUAACCUUCCCUUGUCTT |
73 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3871 |
AGACUAAGCCCAAAAGGGCTT |
GCCCUUUUGGGCUUAGUCUTT |
48 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3875 |
CCUCCCCAUCCCCUUUUAATT |
UUAAAAGGGGAUGGGGAGGTT |
81 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3879 |
AUCAGAGGGAGGUCUUAGATT |
UCUAAGACCUCCCUCUGAUTT |
73 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3883 |
GGGAGGUCUUAGAAAACACTT |
GUGUUUUCUAAGACCUCCCTT |
84 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3887 |
GGCUUAGUCACUCCUCUUCTT |
GAAGAGGAGUGACUAAGCCTT |
71 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3891 |
ACCUUAAGGACCACCGGAUTT |
AUCCGGUGGUCCUUAAGGUTT |
77 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3895 |
CGGAUCUACACCUUCAAGATT |
UCUUGAAGGUGUAGAUCCGTT |
73 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3899 |
UACCGAGAAUGAGCCUGAUTT |
AUCAGGCUCAUUCUCGGUATT |
57 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3903 |
GCUUUAAGGAACUGGAAGGTT |
CCUUCCAGUUCCUUAAAGCTT |
38 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3907 |
UCCUCGUCGUCUGUUCUAATT |
UUAGAACAGACGACGAGGATT |
86 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3911 |
UUCUAACCGGGCAGCUUCUTT |
AGAAGCUGCCCGGUUAGAATT |
73 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3915 |
GAGGAUGGAUUCGACUUAGTT |
CUAAGUCGAAUCCAUCCUCTT |
95 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3919 |
UAAAGCUGGAAAGGGACGGTT |
CCGUCCCUUUCCAGCUUUATT |
67 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3923 |
GGAAGUAAGGACCAGAGACTT |
GUCUCUGGUCCUUACUUCCTT |
45 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3927 |
AAGGCCAACCGAUACUUCUTT |
AGAAGUAUCGGUUGGCCUUTT |
70 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3931 |
GUUCACGUCCUACCCCUUUTT |
AAAGGGGUAGGACGUGAACTT |
67 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3935 |
AGAGUUGGGAUUAGGGCUUTT |
AAGCCCUAAUCCCAACUCUTT |
71 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3939 |
UUACAAAGGAUCUCCUCCCTT |
GGGAGGAGAUCCUUUGUAATT |
81 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3943 |
AACAGCCUUACCCCGAUUCTT |
GAAUCGGGGUAAGGCUGUUTT |
70 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3947 |
UUACCCCGAUUCAGCCUCUTT |
AGAGGCUGAAUCGGGGUAATT |
84 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3951 |
UAACCCCAAGAACGGGCUUTT |
AAGCCCGUUCUUGGGGUUATT |
75 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3955 |
CUAGUCGAAAGAAAACGGGTT |
CCCGUUUUCUUUCGACUAGTT |
57 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3959 |
AGGACGGUACUUUCGAAAGTT |
CUUUCGAAAGUACCGUCCUTT |
46 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3963 |
GUAUCCGAAGACGAAGCUATT |
UAGCUUCGUCUUCGGAUACTT |
97 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3967 |
AGAGAGGUGGAGGUAUCUCTT |
GAGAUACCUCCACCUCUCUTT |
91 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3971 |
GAAAACGCUUGUAAAGCCGTT |
CGGCUUUACAAGCGUUUUCTT |
58 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3975 |
GCUGAACUAGUCGAAAGAATT |
UUCUUUCGACUAGUUCAGCTT |
81 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3979 |
GGAAGAAGAUAGAGCAUCCTT |
GGAUGCUCUAUCUUCUUCCTT |
38 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3983 |
AUCUACCCAGCUCUCCCUUTT |
AAGGGAGAGCUGGGUAGAUTT |
79 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3987 |
AGCGAUCCCGAACAAGUAUTT |
AUACUUGUUCGGGAUCGCUTT |
87 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3991 |
CGAAAGUGUAUCCGAAGACTT |
GUCUUCGGAUACACUUUCGTT |
77 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3995 |
CCGAAGACGAAGCUAUGAATT |
UUCAUAGCUUCGUCUUCGGTT |
48 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM3999 |
UCUCCCACCCAAUGGAGAU |
AUCUCCAUUGGGUGGGAGATT |
83 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4003 |
AAACCAGGAAGGGGAAAUCTT |
GAUUUCCCCUUCCUGGUUUTT |
69 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4007 |
GAAGGGGAAAUCUGUGGUUTT |
AACCACAGAUUUCCCCUUCTT |
66 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4011 |
GGGAGGAUGACAAAGAAGCTT |
GCUUCUUUGUCAUCCUCCCTT |
86 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4015 |
GAAACUGGUACUUUCCCCCTT |
GGGGGAAAGUACCAGUUUCTT |
90 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4019 |
AUCGCUGCUCCUCCUCCUCTT |
GAGGAGGAGGAGCAGCGAUTT |
72 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4023 |
AGCUCUUUGUCACCUCUCUTT |
AGAGAGGUGACAAAGAGCUTT |
39 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4027 |
AAUAAGCAGCUCGCGCUCCTT |
GGAGCGCGAGCUGCUUAUUTT |
58 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4031 |
CUAGAGGAUCUUGAAGACCTT |
GGUCUUCAAGAUCCUCUAGTT |
97 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4035 |
AUCGACCUGAAGGAGUACGTT |
CGUACUCCUUCAGGUCGAUTT |
32 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4039 |
CCCUCCCCUGUCCCCGCUUTT |
AAGCGGGGACAGGGGAGGGTT |
75 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4043 |
UUUGAUCAGCGGAGACUCGTT |
CGAGUCUCCGCUGAUCAAATT |
94 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4047 |
AGUUAACCCGGGACUUGGATT |
UCCAAGUCCCGGGUUAACUTT |
93 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4051 |
AUCACAAACCCCUAGAGGGTT |
CCCUCUAGGGGUUUGUGAUTT |
77 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4055 |
AAACCCCUAGAGGGCAAGUTT |
ACUUGCCCUCUAGGGGUUUTT |
84 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4059 |
GGAACCUCACAUCAACGCGCATT |
UGCGCGUUGAUGUGAGGUUCCTT |
70 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4063 |
UGAACGUCACCGAGGAGAATT |
UUCUCCUCGGUGACGUUCATT |
87 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4067 |
AACCCAAAGGGGAGUUGCUTT |
AGCAACUCCCCUUUGGGUUTT |
97 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4071 |
AAAGGGGAGUUGCUGGAAGTT |
CUUCCAGCAACUCCCCUUUTT |
77 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4075 |
AAACGUGACUUUGGUUCCUTT |
AGGAACCAAAGUCACGUUUTT |
86 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4079 |
GAAUAACCUGAACGUCACCTT |
GGUGACGUUCAGGUUAUUCTT |
72 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4083 |
ACGUCACCGAGGAGAAGUATT |
UACUUCUCCUCGGUGACGUTT |
81 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4087 |
AGAAGUACCAGGAGGCGUUTT |
AACGCCUCCUGGUACUUCUTT |
62 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4091 |
AAACCUCAGCCCUAACGGUTT |
ACCGUUAGGGCUGAGGUUUTT |
71 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4095 |
UUAAGGAGAAGCUGACGGCTT |
GCCGUCAGCUUCUCCUUAATT |
87 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4099 |
AACUUCUGGGAGCCUCCAATT |
UUGGAGGCUCCCAGAAGUUTT |
75 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4103 |
CCAGCGAGCCCAAAAGAAATT |
UUUCUUUUGGGCUCGCUGGTT |
87 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4107 |
CUCAAAUCAAGGCCGGAGUTT |
ACUCCGGCCUUGAUUUGAGTT |
86 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4111 |
AGCCUCCAAACUCCUAGCUTT |
AGCUAGGAGUUUGGAGGCUTT |
71 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4115 |
AUACUUGGCGGGCUCUUUCTT |
GAAAGAGCCCGCCAAGUAUTT |
73 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4119 |
UUGGGGAAGCGGCCGGCGGTT |
CCGCCGGCCGCUUCCCCAATT |
84 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4123 |
AAGGCAUGCUUCGGAAACUTT |
AGUUUCCGAAGCAUGCCUUTT |
96 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4127 |
GCUUCGGAAACUGGACAUCTT |
GAUGUCCAGUUUCCGAAGCTT |
91 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4131 |
AACUCUACUGUGGAGUCGGTT |
CCGACUCCACAGUAGAGUUTT |
73 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4135 |
AGAAACGCAGUAAUCCGGATT |
UCCGGAUUACUGCGUUUCUTT |
87 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4139 |
GGAAGUCCACCUUCUCCGATT |
UCGGAGAAGGUGGACUUCCTT |
55 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4143 |
CUCCGACAGAUGAAGGAAATT |
UUUCCUUCAUCUGUCGGAGTT |
73 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4147 |
AAGGACCUAGAGGAGUCACTT |
GUGACUCCUCUAGGUCCUUTT |
83 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4151 |
CUGACCGGAAGCGCUUAAATT |
UUUAAGCGCUUCCGGUCAGTT |
90 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4155 |
GAAGAGCCUACACAACCCUTT |
AGGGUUGUGUAGGCUCUUCTT |
76 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4159 |
ACAGAAAGAGUUCGAGGAGTT |
CUCCUCGAACUCUUUCUGUTT |
65 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4163 |
AGGAGACCGUGACAUUUCGTT |
CGAAAUGUCACGGUCUCCUTT |
0 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4167 |
ACCUUAAGGACCACCGGAUTT |
AUCCGGUGGUCCUUAAGGUTT |
73 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4171 |
CGGAUCUACACCUUCAAGATT |
UCUUGAAGGUGUAGAUCCGTT |
44 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4175 |
GCUUUAAGGAACUGGAAGGTT |
CCUUCCAGUUCCUUAAAGCTT |
77 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4179 |
GAGAGAGACGGUGGAAGAATT |
UUCUUCCACCGUCUCUCUCTT |
75 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4183 |
AUCCUGCAGAAGAAGCCUCTT |
GAGGCUUCUUCUGCAGGAUTT |
53 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4187 |
UCCUCGUCGUCUGUUCUAATT |
UUAGAACAGACGACGAGGATT |
84 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4191 |
AACCCACCACAGCUAGAACUU |
GUUCUAGCUGUGGUGGGUUUU |
89 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4195 |
UUACAAAGGAUCUCCUCCCTT |
GGGAGGAGAUCCUUUGUAATT |
77 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4199 |
AAACGAGAGAGCCCACCUUTT |
AAGGUGGGCUCUCUCGUUUTT |
58 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4203 |
AAAGCGGUGGAUCAGCUCUTT |
AGAGCUGAUCCACCGCUUUTT |
69 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4207 |
UCCAAGCUUCCUCGUUGGUTT |
ACCAACGAGGAAGCUUGGATT |
71 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4211 |
AGAGAGGUGGAGGUAUCUCTT |
GAGAUACCUCCACCUCUCUTT |
90 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4215 |
CCGAAGACGAAGCUAUGAATT |
UUCAUAGCUUCGUCUUCGGTT |
73 percent target mRNA inhibition |
13 nM |
US20120088815A1, EP2415869A1 |
SM4231 |
AACCUUACCCACCUCAUGUAUCU |
AGAUACAUGAGGUGGGUAAGGUU |
86 percent target mRNA inhibition |
17 nM |
25233814 |
SM4250 |
AACCUUACCCACCUCAUGUAUCU |
AGAUACAUGAGGUGGGUAAGGUU |
97 percent target mRNA inhibition |
17 nM |
25233814 |
SM4297 |
AAGUAAGGACCAGAGACAAA |
UUUGUCUCUGGUCCUUACUU |
55 percent target mRNA inhibition |
1.5 nM |
15974578 |
SM4452 |
GGCCUUUCACUACUCCUACGA |
GUAGGAGUAGUGAAAGGCCAG |
82 percent target mRNA inhibition |
1 nM |
21985606 |
SM4457 |
GGCCUUUCACUACUCCUACGA |
GUAGGAGUAGUGAAAGGCCAG |
0 percent target mRNA inhibition |
100 nM |
21985606 |
SM4460 |
UCCUACAGCACAACAAAUGUG |
CAUUUGUUGUGCUGUAGGAAG |
50 percent target mRNA inhibition |
50 uM |
21985606 |
SM4466 |
UCCUACAGCACAACAAAUGUG |
CAUUUGUUGUGCUGUAGGAAG |
35 percent target mRNA inhibition |
50 uM |
21985606 |
SM4472 |
UCCUACAGCACAACAAAUGUG |
CAUUUGUUGUGCUGUAGGAAG |
0 percent target mRNA inhibition |
1 uM |
21985606 |
SM4478 |
UCCUACAGCACAACAAAUGUG |
CAUUUGUUGUGCUGUAGGAAG |
0 percent target mRNA inhibition |
1 uM |
21985606 |
SM4533 |
GGCCUUUCACUACUCCUACGA |
GUAGGAGUAGUGAAAGGCCAG |
58 percent target mRNA inhibition |
0.2 nM |
22236254 |
SM4597 |
GGCCUUUCACUACUCCUACTT |
AGUAGGAGUAGUGAAAGGCCTT |
97 percent target mRNA inhibition |
33 nM |
22372696 |
SM4606 |
UAAGGCUAUGAAGAGAUACTT |
AGUAUCUCUUCAUAGCCUUATT |
1 percent target mRNA inhibition |
33 nM |
22372696 |
SM4607 |
GGCCUUUCACUACUCCUACGA |
GUAGGAGUAGUGAAAGGCCAG |
NA |
NA |
22494497 |
SM4608 |
CUGGCCUUUCACUACUCCUACGAGCAC |
GUGCUCGUAGGAGUAGUGAAAGGCCAG |
NA |
NA |
22494497 |
SM4615 |
UCCUACAGCACAACAAAUGUG |
CAUUUGUUGUGCUGUAGGAAG |
NA |
NA |
22494497 |
SM4616 |
CUUCCUACAGCACAACAAAUGUGAAUG |
CAUUCACAUUUGUUGUGCUGUAGGAAG |
NA |
NA |
22494497 |
SM4619 |
GGCCUUUCACUACUCCUACGA |
GUAGGAGUAGUGAAAGGCCAG |
82 percent target mRNA inhibition |
1 nM |
22494497 |
SM4623 |
CUGGCCUUUCACUACUCCUACGAGCAC |
GUGCUCGUAGGAGUAGUGAAAGGCCAG |
80 percent target mRNA inhibition |
1 nM |
22494497 |
SM4627 |
GGCCUUUCACUACUCCUACGA |
GUAGGAGUAGUGAAAGGCCAG |
58 percent target mRNA inhibition |
0.2 nM |
22494497 |
SM4631 |
CUGGCCUUUCACUACUCCUACGAGCAC |
GUGCUCGUAGGAGUAGUGAAAGGCCAG |
69 percent target mRNA inhibition |
0.2 nM |
22494497 |
SM4635 |
GGCCUUUCACUACUCCUACGA |
GUAGGAGUAGUGAAAGGCCAG |
12 percent target mRNA inhibition |
600 nM |
22494497 |
SM4639 |
CUGGCCUUUCACUACUCCUACGAGCAC |
GUGCUCGUAGGAGUAGUGAAAGGCCAG |
0 percent target mRNA inhibition |
600 nM |
22494497 |
SM4643 |
GGCCUUUCACUACUCCUACGA |
GUAGGAGUAGUGAAAGGCCAG |
0 percent target mRNA inhibition |
50 nM |
22494497 |
SM4647 |
CUGGCCUUUCACUACUCCUACGAGCAC |
GUGCUCGUAGGAGUAGUGAAAGGCCAG |
0 percent target mRNA inhibition |
50 nM |
22494497 |
SM4651 |
UCCUACAGCACAACAAAUGUG |
CAUUUGUUGUGCUGUAGGAAG |
75 percent target mRNA inhibition |
100 nM |
22494497 |
SM4653 |
CUUCCUACAGCACAACAAAUGUGAAUG |
CAUUCACAUUUGUUGUGCUGUAGGAAG |
90 percent target mRNA inhibition |
100 nM |
22494497 |
SM4655 |
UCCUACAGCACAACAAAUGUG |
CAUUUGUUGUGCUGUAGGAAG |
13 percent target mRNA inhibition |
100 nM |
22494497 |
SM4657 |
CUUCCUACAGCACAACAAAUGUGAAUG |
CAUUCACAUUUGUUGUGCUGUAGGAAG |
36 percent target mRNA inhibition |
100 nM |
22494497 |
SM4659 |
CUUACGCUGAGUACUUCGATT |
UCGAAGUACUCAGCGUAAGTT |
96 percent target mRNA inhibition |
13 nM |
US 20080249039 A1 |
SM4679 |
NNNNNNNNNNNNNNNNNNNNNN |
NNNNNNNNNNNNNNNNNNNNNN |
70 percent target mRNA inhibition |
30 nM |
EP2548962A1 |
SM4688 |
NNNNNNNNNNNNNNNNNNNNNN |
NNNNNNNNNNNNNNNNNNNNNN |
55 percent target mRNA inhibition |
30 nM |
EP2548962A1 |
SM4828 |
UGAAUCAGAAGAUGAAGUCAA |
GACUUCAUCUUCUGAUUCAAG |
60 percent target mRNA inhibition |
2 nmol/l |
23820891 |
SM4832 |
UGAAUCAGAAGAUGAAGUCAA |
GACUUCAUCUUCUGAUUCAAG |
94 percent target mRNA inhibition |
2 nmol/l |
23820891 |
SM4836 |
UAACUAGAGAUCCCUCAGACC |
UCUGAGGGAUCUCUAGUUACC |
IC-50 1.6 (pmol/l) for target mRNA |
NA |
23820891 |
SM4837 |
GUAACUAGAGAUCCCUCAGAC |
CUGAGGGAUCUCUAGUUACCA |
IC-50 0.8(pmol/l) for target mRNA |
NA |
23820891 |
SM4838 |
AACUAGAGAUCCCUCAGACCC |
GUCUGAGGGAUCUCUAGUUAC |
IC-50 2.3 (pmol/l) for target mRNA |
NA |
23820891 |
SM4855 |
GCGCGCUUUGUAGGAUUCGTT |
CGAAUCCUACAAAGCGCGCTT |
0 percent target mRNA inhibition |
25 nM |
15919084 |
SM4856 |
CGUACGCGGAAUACUUCGATT |
UCGAAGUAUUCCGCGUACGTT |
95.4 percent target mRNA inhibition (IC-50 = 0.10 nM) |
25 nM |
15919084 |
SM4877 |
CGUACGCGGAAUACUUCGATT |
UCGAAGUAUUCCGCGUACGTT |
95.4 percent target mRNA inhibition |
25 nM |
17150641 |
SM4885 |
AAACAUGCAGAAAAUGCUGTT |
CAGCAUUUUCUGCAUGUUUTT |
41.7 percent target mRNA inhibition |
25 nM |
17150641 |
SM4893 |
CGUACGCGGAAUACUUCGATT |
UCGAAGUAUUCCGCGUACGTT |
95.4 percent target mRNA inhibition |
25 nM |
17924376 |
SM4912 |
CGUACGCGGAAUACUUCGATT |
UCGAAGUAUUCCGCGUACGTT |
95.4 percent target mRNA inhibition |
25 nM |
17924376 |
SM4932 |
AAACAUGCAGAAAAUGCUGTT |
CAGCAUUUUCUGCAUGUUUTT |
41.7 percent target mRNA inhibition |
25 nM |
17924376 |
SM4951 |
AAACAUGCAGAAAAUGCCUTT |
CAGCAUUUUCUGCAUGUUUTT |
69.7 percent target mRNA inhibition |
25 nM |
17924376 |