VIRsiRNAid | siRNA Sequence | Virus_Name | Target Region | Cell Line | Test Object | Efficacy | PMID | Offtarget | Align With | ALIGN0 Result |
virsi1769 | guaaccgaaaucgguugaacc | Human Papillomavirus [HPV] | P97 of E6/E7 | SiHa | mRNA | 50 | 19826423 | Blast SL | refseqs |       |
virsi2168 | uccauaugcuguaugugau | Human Papillomavirus [HPV] | E7 | CaSki | mRNA | Low | 16611884 | Blast SL | refseqs |       |
virsi1717 | cauuuaccagcccgacgag | Human Papillomavirus [HPV] | E7 | HeLa | Protein | High | 17589817 | Blast SL | refseqs |       |
virsi1711 | ccaccaacgucacacaaugu | Human Papillomavirus [HPV] | E7 | HeLa | Protein | High | 17636212 | Blast SL | refseqs |       |
virsi2167 | gcacacacguagacauucg | Human Papillomavirus [HPV] | E7 | CaSki | Protein | High | 16611884 | Blast SL | refseqs |       |
virsi1718 | ccacaacgucacacaaugu | Human Papillomavirus [HPV] | E7 | HeLa | Protein | 100 | 17589817 | Blast SL | refseqs |       |
virsi1715 | aggaggaugaaauagauggu | Human Papillomavirus [HPV] | E7 | CaSki | RNA | 100 | 19174559 | Blast SL | refseqs |       |
virsi1743 | cacgagcaauuaagcga | Human Papillomavirus [HPV] | E7 | HeLa | mRNA | 91 | 20885450 | Blast SL | refseqs |       |
virsi1766 | gcauggagauacaccuaca | Human Papillomavirus [HPV] | E7 | CaSki | Protein | 88 | 18060502 | Blast SL | refseqs |       | Pubmed:
18060502 Article:
RNA interference against HPV16 E7 oncogene leads to viral E6 and E7 suppression in cervical cancer cells and apoptosis via upregulation of Rb and p53.Authors:
Sima N, Wang W, Kong D, Deng D, Xu Q, Zhou J, Xu G, Meng L, Lu Y, Wang S, Ma D.Journal:
Apoptosis. 2008 Feb;13(2):273-81.Entrez:
18060502
virsi1731 | ggaagaaaacgaugaaaua | Human Papillomavirus [HPV] | E7 | HeLa | mRNA | 85 | 15908516 | Blast SL | refseqs |       |
virsi1767 | aggaggaugaaauagaugg | Human Papillomavirus [HPV] | E7 | SiHa | mRNA | 85 | 15665592 | Blast SL | refseqs |       |
virsi1740 | ucucuacuguuaugagcaauua | Human Papillomavirus [HPV] | E7 | HeLa | mRNA | 82 | 20885450 | Blast SL | refseqs |       |
virsi1730 | ggcaacauugcaagacauu | Human Papillomavirus [HPV] | E7 | HeLa | mRNA | 80 | 15908516 | Blast SL | refseqs |       |
virsi1768 | gcacacacguagacauucg | Human Papillomavirus [HPV] | E7 | CaSki | Protein | 77 | 16369495 | Blast SL | refseqs |       |
virsi1760 | cuucgguugugcguacaaagc | Human Papillomavirus [HPV] | E7 | SiHa | mRNA | 76 | 18157144 | Blast SL | refseqs |       | Pubmed:
18157144 Article:
New highly potent and specific E6 and E7 siRNAs for treatment of HPV16 positive cervical cancer.Authors:
Yamato K, Yamada T, Kizaki M, Ui-Tei K, Natori Y, Fujino M, Nishihara T, Ikeda Y, Nasu Y, Saigo K, Yoshinouchi M.Journal:
Cancer Gene Ther. 2008 Mar;15(3):140-53. Epub 2007 Dec 21.Entrez:
18157144
virsi1690 | auagugaccuguugcugug | Human Papillomavirus [HPV] | E7 | B16-BL6 | mRNA | 75 | 19887612 | Blast SL | refseqs |       | Pubmed:
19887612 Article:
Epigenetic silencing of interferon-kappa in human papillomavirus type 16-positive cells.Authors:
Rincon-Orozco B, Halec G, Rosenberger S, Muschik D, Nindl I, Bachmann A, Ritter TM, Dondog B, Ly R, Bosch FX, Zawatzky R, Rösl F.Journal:
Cancer Res. 2009 Nov 15;69(22):8718-25. Epub 2009 Nov 3.Entrez:
19887612
virsi1689 | acaagacgcacaaccuuua | Human Papillomavirus [HPV] | E7 | B16-BL6 | mRNA | 74 | 19887612 | Blast SL | refseqs |       | Pubmed:
19887612 Article:
Epigenetic silencing of interferon-kappa in human papillomavirus type 16-positive cells.Authors:
Rincon-Orozco B, Halec G, Rosenberger S, Muschik D, Nindl I, Bachmann A, Ritter TM, Dondog B, Ly R, Bosch FX, Zawatzky R, Rösl F.Journal:
Cancer Res. 2009 Nov 15;69(22):8718-25. Epub 2009 Nov 3.Entrez:
19887612
virsi1759 | gcccauuacaauauuguaacc | Human Papillomavirus [HPV] | E7 | SiHa | mRNA | 74 | 18157144 | Blast SL | refseqs |       | Pubmed:
18157144 Article:
New highly potent and specific E6 and E7 siRNAs for treatment of HPV16 positive cervical cancer.Authors:
Yamato K, Yamada T, Kizaki M, Ui-Tei K, Natori Y, Fujino M, Nishihara T, Ikeda Y, Nasu Y, Saigo K, Yoshinouchi M.Journal:
Cancer Gene Ther. 2008 Mar;15(3):140-53. Epub 2007 Dec 21.Entrez:
18157144
virsi1761 | caccuacauugcaugaauaua | Human Papillomavirus [HPV] | E7 | SiHa | mRNA | 71 | 18157144 | Blast SL | refseqs |       | Pubmed:
18157144 Article:
New highly potent and specific E6 and E7 siRNAs for treatment of HPV16 positive cervical cancer.Authors:
Yamato K, Yamada T, Kizaki M, Ui-Tei K, Natori Y, Fujino M, Nishihara T, Ikeda Y, Nasu Y, Saigo K, Yoshinouchi M.Journal:
Cancer Gene Ther. 2008 Mar;15(3):140-53. Epub 2007 Dec 21.Entrez:
18157144
virsi1739 | cucuacuguuaugagc | Human Papillomavirus [HPV] | E7 | HeLa | mRNA | 69 | 20885450 | Blast SL | refseqs |       |
virsi1758 | ccggacagagcccauuacaau | Human Papillomavirus [HPV] | E7 | SiHa | mRNA | 68 | 18157144 | Blast SL | refseqs |       | Pubmed:
18157144 Article:
New highly potent and specific E6 and E7 siRNAs for treatment of HPV16 positive cervical cancer.Authors:
Yamato K, Yamada T, Kizaki M, Ui-Tei K, Natori Y, Fujino M, Nishihara T, Ikeda Y, Nasu Y, Saigo K, Yoshinouchi M.Journal:
Cancer Gene Ther. 2008 Mar;15(3):140-53. Epub 2007 Dec 21.Entrez:
18157144
virsi1748 | gcaauuaaaugacagcuca | Human Papillomavirus [HPV] | E7 | CaSki | mRNA | 67 | 18755502 | Blast SL | refseqs |       |
virsi1742 | uucuaugucacgagcaa | Human Papillomavirus [HPV] | E7 | HeLa | mRNA | 63 | 20885450 | Blast SL | refseqs |       |
virsi1750 | gacagagcccauuacaaua | Human Papillomavirus [HPV] | E7 | CaSki | mRNA | 60 | 18755502 | Blast SL | refseqs |       |
virsi1691 | cgcgguucauaaagcuaaa | Human Papillomavirus [HPV] | E7 | B16-BL6 | mRNA | 58 | 19887612 | Blast SL | refseqs |       | Pubmed:
19887612 Article:
Epigenetic silencing of interferon-kappa in human papillomavirus type 16-positive cells.Authors:
Rincon-Orozco B, Halec G, Rosenberger S, Muschik D, Nindl I, Bachmann A, Ritter TM, Dondog B, Ly R, Bosch FX, Zawatzky R, Rösl F.Journal:
Cancer Res. 2009 Nov 15;69(22):8718-25. Epub 2009 Nov 3.Entrez:
19887612