Searching haptens, carrier proteins, and anti-hapten antibodies.

Srivastava, Shilpy and Singh, Mahender Kumar and Raghava, G.P.S. and Varshney, Grish C (2007) Searching haptens, carrier proteins, and anti-hapten antibodies. Methods in molecular biology (Clifton, N.J.), 409. pp. 125-39. ISSN 1064-3745

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Haptens are small molecules that are usually nonimmunogenic unless coupled to some carrier proteins. The generation of anti-hapten antibodies is important for the development of immunodiagnostics and therapeutics. Recently, our group has developed a database called HaptenDB, which provides comprehensive information about 1,087 haptens. In this chapter, we describe following web tools integrated in HaptenDB: (i) keyword search facility allows search on major fields, (ii) browsing service, to display all haptens, carrier proteins and antibodies, and (iii) structure similarity search, which allows the users to search their structure against hapten structures.

Item Type: Article
Additional Information: Copyright of this article belongs to Springer Science
Subjects: Q Science > QH Natural history > QH301 Biology
QH301 Biology
Depositing User: Dr. K.P.S.Sengar
Date Deposited: 08 Dec 2011 19:39
Last Modified: 08 Dec 2011 19:39

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