Feasibility and uniqueness of stationary states of nonideal recombinant fermentations<span style='mso-spacerun:yes'>

Patnaik, P R (2005) Feasibility and uniqueness of stationary states of nonideal recombinant fermentations<span style='mso-spacerun:yes'>. Reaction Kinetics and Catalysis Letters, 87 (1). pp. 11-18. ISSN 0133-1736

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Official URL: http://dx.doi.org/10.1007/s11144-006-0003-9

Abstract

Summary In recombinant fermentations the plasmid loss probability per generation depends on the specific growth rate, which is related linearly to the dilution rate. A model with this feature and incomplete mixing has been studied analytically for stationary state behavior. While the kinetic parameters place upper limits on the dilution rate for a feasible stationary state in a well-mixed bioreactor, the feasible and nonfeasible regions for an incompletely mixed reactor are separated by either a straight line or a plane, whose position is determined by the mixing conditions.

Item Type: Article
Additional Information: Copyright of this article belongs to Springer Science+Business Media B.V.
Uncontrolled Keywords: recombinant bacteria, Continuous fermentation, variable plasmid loss, fluid mixing, stationary states
Subjects: Q Science > QD Chemistry
Depositing User: Dr. K.P.S.Sengar
Date Deposited: 17 Feb 2012 16:47
Last Modified: 17 Feb 2012 16:47
URI: http://crdd.osdd.net/open/id/eprint/1004

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